Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability by Wei-Ching Liang, Hongkang Xi, Dawei Sun, Luigi D’Ascenzo, Jonathan Zarzar, Nicole Stephens, Ryan Cook, Yinyin Li, Zhengmao Ye, Marissa Matsumoto, Jian Payandeh, Matthieu Masureel, Yan Wu

Subjects: Get full text

Design and Synthesis of Crystalline Al-Doped TiO₂ Buffer Layers for Enhancing Energy Conversion Efficiency of New Photovoltaic Devices by Dongin Kim, Jiwon Lee, Rakhyun Jeong, Ki-Hwan Hwang, Jin-Hyo Boo

Subjects: “…perovskite solar cell…”
Get full text

Therapeutic Efficacy of Intranasal <i>N</i>-Acetyl-L-Cysteine with Cell-Penetrating Peptide-Modified Polymer Micelles on Neuropathic Pain in Partial Sciatic Nerve Ligation Mice by Hiroshi Nango, Ai Takahashi, Naoto Suzuki, Takumi Kurano, Saia Sakamoto, Taiki Nagatomo, Toyofumi Suzuki, Takanori Kanazawa, Yasuhiro Kosuge, Hiroko Miyagishi

Subjects: Get full text

Revealing the core suppression effects of various Di (2-ethylhexyl) phthalate exposure on early meiosis progression in postnatal male mice via single-cell RNA sequencing by Baoquan Han, Lei Hua, Shuai Yu, Wei Ge, Cong Huang, Yu Tian, Chunxiao Li, Jiamao Yan, Tian Qiao, Jiachen Guo, Dongliang Lu, Bin Wang, Diya Cai, Yunqi Zhang, Shaolin Liang, Jianjuan Zhao, Qi Hou, Wei Shen, Zhongyi Sun

Subjects: Get full text

Nomogram model using serum Club cell secretory protein 16 to predict prognosis and acute exacerbation in patients with idiopathic pulmonary fibrosis by Yaqiong Tian, Xuan Zhou, Mi Tian, Lijun Ren, Ruyi Zou, Hanyi Jiang, Miaomiao Xie, Mei Huang, Jingjing Ding, Yin Liu, Jingyu Chen, Min Cao, Hourong Cai

Subjects: Get full text

Cancer-associated thoracic aorta arterial thrombosis: case report and review of the literature by Miguel Borregón, María Valero, Asia Ferrández, Álvaro Muñoz, Carmen Roque, Javier-David Benítez-Fuentes

Subjects: Get full text

Activity of oxidative processes and the state of the redox regulating system in tumor tissue in skin cancer by I. A. Goroshinskaya, E. M. Frantsiyants, N. I. Larina, Yu. V. Przhedetskiy, I. V. Kaplieva, L. A. Nemashkalova, V. A. Bandovkina, V. V. Pozdnyakova, V. Yu. Przhedetskaya

Subjects: “…basal cell carcinoma of skin…”
Get full text

Shuangshen Granules Suppress Myeloid-derived Suppressor Cell-mediated Lung Premetastatic Niche Development by Targeting Sphingosine-1-Phosphate Receptor-1/Signal Transducer, Activa... by Rui Liu, Jia-Qi Hu, Xing Zhang, Xiao-Yi Wu, Hua-Min Wei, Yuan-Chen Zhao, Shu-Lin He, Jing Yu, Xin Qi, Ying-Xia Pei, Hong Chen, Wei-Dong Li, Bao-Jin Hua

Subjects: “…myeloid-derived suppressor cell…”
Get full text

A network comparison on efficacy and safety profiling of PD-1/PD-L1 inhibitors in first-line treatment of advanced non-small cell lung cancer by Jie Fu, Jie Fu, Yi-Dan Yan, Xu Wan, Xiao-Fan Sun, Xiao-Fan Sun, Xiu-Mei Ma, Ying-Jie Su

Subjects: Get full text

Set of 15 SNP-SNP Markers for Detection of Unbalanced Degraded DNA Mixtures and Noninvasive Prenatal Paternity Testing by Ranran Zhang, Yu Tan, Li Wang, Hui Jian, Jing Zhu, Yuanyuan Xiao, Mengyu Tan, Jiaming Xue, Fan Yang, Fan Yang, Weibo Liang

Subjects: Get full text

Evaluation of peptide secondary structure and intracellular uptake by introducing disubstituted amino acids into the amphipathic helical peptide C18AA by Takuma Kato, Go Ofuka, Ryota Kobayashi, Akiko Asano, Mitsunobu Doi

Subjects: “…Cell-penetrating peptide…”
Get full text

PURITY TESTING OF ARRIAH FMD VACCINES by D. A. Lozovoy, D. V. Mikhalishin, V. A. Starikov, M. I. Doronin, A. S. Sharypov

Subjects: Get full text

Phα1β interaction with the Kv11.1 potassium channel in HEK293 cells transfected with the human ERG channel by João B. Calixto, Adara Aurea dos Santos, Juliano Ferreira, Alessandra Hubner Souza, Célio José de Castro Junior, Marcus Vinicius Gomez

Subjects: Get full text

Changes in donor lymphocyte infusion for relapsed patients post-hematopoietic stem cell transplantation: a 30-year single-center experience by Yusuke Uchibori, Shuhei Kurosawa, Yuho Najima, Kyoko Haraguchi, Daichi Sadato, Chizuko Hirama, Yasutaka Sadaga, Kaori Kondo, Chika Kato, Satoshi Sakai, Yasuhiro Kambara, Fumihiko Ouchi, Masashi Shimabukuro, Atsushi Jinguji, Naoki Shingai, Takashi Toya, Hiroaki Shimizu, Takeshi Kobayashi, Hironori Harada, Hironori Harada, Yuka Harada, Yoshiki Okuyama, Noriko Doki

Subjects: Get full text

Features of expression of immunohistochemical markers in local and generalized clear cell kidney cancer by E. M. Frantsiyants, A. N. Shevchenko, E. A. Dzhenkova, N. S. Karnaukhov, T. A. Gudtskova, A. A. Breus, E. V. Filatova, D. A. Shvyrev

Subjects: “…light cell kidney cancer…”
Get full text

IINS Vs CALLY Index: A Battle of Prognostic Value in NSCLC Patients Following Surgery by Cheng H, Ma J, Zhao F, Liu Y, Wu J, Wu T, Li H, Zhang B, Liu H, Fu J, He H, Zhu C, Ren H, Yang C, Qin S

Subjects: “…non-small cell lung cancer (nsclc)…”
Get full text

DEVELOPMENT AND USE OF THE COMPETITIVE ELISA-BASED TEST SYSTEM FOR DETECTION OF ANTIBODIES TO GROUP A ROTAVIRUS IN LIVESTOCK SERA by O. P. Bjadovskaya, Ye. A. Bukhon, A. A. Nesterov

Subjects: Get full text

Identifying Multiomic Signatures of X‐Linked Retinoschisis‐Derived Retinal Organoids and Mice Harboring Patient‐Specific Mutation Using Spatiotemporal Single‐Cell Transcriptomics... by Yueh Chien, You‐Ren Wu, Chih‐Ying Chen, Yi‐Ping Yang, Lo‐Jei Ching, Bo‐Xuan Wang, Wei‐Chao Chang, I‐Hsun Chiang, Pong Su, Shih‐Yu Chen, Wen‐Chang Lin, I‐Chieh Wang, Tai‐Chi Lin, Shih‐Jen Chen, Shih‐Hwa Chiou

Subjects: Get full text

Evaluating biomarkers in canine cytotoxic interface dermatitis reactions to account for clinical and histopathological similarities and differences by Shriya Kannan, Neil B. Wong, Grace E. Ryan, Nia E. R. James, Ayodeji Ajayi, Janet E. Lubov, Clement N. David, Linda Wrijil, Nicholas A. Robinson, Kelly Hughes, Ramon M. Almela, Jillian M. Richmond

Subjects: “…epitheliotropic lymphoma (EL)/cutaneous T cell lymphoma (CTCL)…”
Get full text

Integrated Analysis of Cell-Free DNA and Novel Protein Biomarkers for Stratification and Therapy Monitoring in Stage IV Pancreatic Cancer: A Preliminary Study by Saskia Hussung, Maria E. Hess, Elham Bavafaye Haghighi, Uwe A. Wittel, Melanie Boerries, Ralph M. Fritsch

Subjects: Get full text