A mutation in RNA polymerase imparts resistance to β-lactams by preventing dysregulation of amino acid and nucleotide metabolism by Yesha Patel, John D. Helmann

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Manipulation of seed coat content for increasing oil content via modulating BnaMYB52 in Brassica napus by Jiang Ye, Xiaowei Wu, Xiang Li, Yuting Zhang, Yuqing Li, Hui Zhang, Jie Chen, Yuyan Xiang, Yefan Xia, Hu Zhao, Zengdong Tan, Liang Guo, Xuan Yao

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The guided fire from within: intratumoral administration of mRNA-based vaccines to mobilize memory immunity and direct immune responses against pathogen to target solid tumors by Renhao Li, Jing-Chu Hu, Li Rong, Yige He, Xiaolei Wang, Xuansheng Lin, Wenjun Li, Yangfan Wu, Chaiyaporn Kuwentrai, Canhui Su, Thomas Yau, Ivan Fan-Ngai Hung, Xiang Gao, Jian-Dong Huang

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The cell autonomous and non-autonomous roles of itaconate in immune response by Chao Chen, Xinjian Li

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ECM29/proteasome-mediated self-antigen generation by CNS-resident neuroglia promotes regulatory T cell activation by Sheng-Wen Chen, Ying Chu, Chien-Hsin Chu, Xuan-Dieu Thi Pham, Hang Pong Ng, Chin-Lin Guo, Pei-Lin Cheng

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Chronic intermittent fasting impairs β cell maturation and function in adolescent mice by Leonardo Matta, Peter Weber, Suheda Erener, Alina Walth-Hummel, Daniela Hass, Lea K. Bühler, Katarina Klepac, Julia Szendroedi, Joel Guerra, Maria Rohm, Michael Sterr, Heiko Lickert, Alexander Bartelt, Stephan Herzig

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Emotional stress increases GluA2 expression and potentiates fear memory via adenylyl cyclase 5 by Qian Yang, Ahmad Abdulla, Muhammad Farooq, Yoshihiro Ishikawa, Siqiong June Liu

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Fate erasure logic of gene networks underlying direct neuronal conversion of somatic cells by microRNAs by Kitra Cates, Luorongxin Yuan, Yan Yang, Andrew S. Yoo

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Plectin, a novel regulator in migration, invasion and adhesion of ovarian cancer by Lanning Bai, Xueqian Qian, Hui Zhang, Yi Yuan, Xiaodong Cui, Min Cheng, Yangyang Han

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Q&A with Ying Wai Chan by Ying Wai Chan

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Detection of early relapse in multiple myeloma patients by Tereza Růžičková, Monika Vlachová, Lukáš Pečinka, Monika Brychtová, Marek Večeřa, Lenka Radová, Simona Ševčíková, Marie Jarošová, Josef Havel, Luděk Pour, Sabina Ševčíková

“…Cell Division…”
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Spatial proteomics identifies a CRTC-dependent viral signaling pathway that stimulates production of interleukin-11 by Benjamin J. Ravenhill, Marisa Oliveira, George Wood, Ying Di, Joanne Kite, Xinyue Wang, Colin T.R. Davies, Yongxu Lu, Robin Antrobus, Gill Elliott, Nerea Irigoyen, David J. Hughes, Paul A. Lyons, Betty Chung, Georg H.H. Borner, Michael P. Weekes

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Single-nucleus RNA sequencing reveals distinct pathophysiological trophoblast signatures in spontaneous preterm birth subtypes by Cherilyn Uhm, Jianlei Gu, Weina Ju, Stephanie Pizzella, Hande Oktay, Joyce Yao-Chun Peng, Sararose Guariglia, Yong Liu, Hongyu Zhao, Yong Wang, Ramkumar Menon, Nanbert Zhong

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KMT2C/KMT2D-dependent H3K4me1 mediates changes in DNA replication timing and origin activity during a cell fate transition by Deniz Gökbuget, Liana Goehring, Ryan M. Boileau, Kayla Lenshoek, Tony T. Huang, Robert Blelloch

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Human epicardial organoids from pluripotent stem cells resemble fetal stage with potential cardiomyocyte- transdifferentiation by Fanwen Wang, Xinle Zou, Huilin Zheng, Tianci Kong, Duanqing Pei

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Mesenchymal Stem Cell-Derived Extracellular Vesicles for Regenerative Applications and Radiotherapy by Ning Wang, Feifei Ma, Huijuan Song, Ningning He, Huanteng Zhang, Jianguo Li, Qiang Liu, Chang Xu

“…Cell Transplantation…”
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Transketolase attenuates the chemotherapy sensitivity of glioma cells by modulating R-loop formation by Minjie Fu, Mengli Zhang, Licheng Zhang, Yuan Feng, Chao Gao, Hao Xu, Jinsen Zhang, Huaichao Zhang, Tianping Peng, Youjun Chu, Yonghe Wu, Pu Wang, Dan Ye, Ying Mao, Wei Hua

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Distinct plasmablast developmental intermediates produce graded expression of IgM secretory transcripts by Evelyn P. Sievert, Marissa C. Franke, Kayla B. Thomas, Yoseop Yoon, Yongsheng Shi, Roger Sciammas

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Non-cell-autonomous regulation of mTORC2 by Hedgehog signaling maintains lipid homeostasis by Kylie R. VanDerMolen, Martin A. Newman, Peter C. Breen, Yunjing Gao, Laura A. Huff, Robert H. Dowen

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Amelioration of premature aging in Werner syndrome stem cells by targeting SHIP/AKT pathway by Hei-Yin Tam, Jiaxing Liu, Tsz-Ching Yiu, Adrian On-Wah Leung, Chang Li, Shen Gu, Owen Rennert, Boxian Huang, Hoi-Hung Cheung

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