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Topography of Genetic Loci in Tissue Samples: Towards New Diagnostic Tool Using Interphase FISH and High-Resolution Image Analysis Techniques
Published 2000-01-01“…It suggests that the arrangement of genetic loci in cell nucleus is conserved in different types of human cells. …”
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A single-cell and spatial wheat root atlas with cross-species annotations delineates conserved tissue-specific marker genes and regulators
Published 2025-02-01“…Summary: Despite the broad use of single-cell/nucleus RNA sequencing in plant research, accurate cluster annotation in less-studied plant species remains a major challenge due to the lack of validated marker genes. …”
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Exposure to nano-polystyrene during pregnancy leads to Alzheimer's disease-related pathological changes in adult offspring
Published 2025-01-01“…Specifically, there was a substantial reduction in neuron cells, significant changes in the number of Nissl bodies, noticeable loss of cell nucleus, and increased presence of neurofibrillary tangles in adult offspring mice exposed to PS-NPs during gestation. …”
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Single-cell atlas reveals multi-faced responses of losartan on tubular mitochondria in diabetic kidney disease
Published 2025-01-01“…Single-nucleus RNA sequencing (snRNA-seq) technology is a high-throughput sequencing analysis technique for RNA at the level of a single cell nucleus. Here, our DKD mouse kidney single-cell RNA sequencing conveys a more comprehensive mitochondrial profile, which helps us further understand the therapeutic response of this unique organelle family to drugs. …”
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