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121
Identification of new genes regulating nodule development in Medicago truncatula: an in-silico approach
Published 2024-09-01“…This results in the formation of structure named infection thread and initiation of cell division in root cortex and finally formation of functional nodules. …”
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122
A functional SNP of the core promoter region within goat CDC25A gene affects litter size
Published 2025-02-01“…The Cell division cycle 25A (CDC25A) gene has been considered as a candidate gene associated with reproductive traits for goat breeding. …”
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123
E46K α-Synuclein Mutation Fails to Promote Neurite Outgrowth by Not Inducing Cdc42EP2 Expression, Unlike Wild-Type or A53T α-Synuclein in SK-N-SH Cells
Published 2024-12-01“…We also analyzed the differential regulation of cell division control 42 effector protein 2 (Cdc42EP2) using real-time quantitative polymerase chain reaction and western blot analysis. …”
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124
Establishment of probabilistic model for Salmonella Enteritidis growth and inactivation under acid and osmotic pressure
Published 2017-12-01“…Meanwhile, a probabilistic model based on the theory of cell division and mortality was established to predict the growth or inactivation of S. …”
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125
WIPI-1 Positive Autophagosome-Like Vesicles Entrap Pathogenic Staphylococcus aureus for Lysosomal Degradation
Published 2012-01-01“…By confocal and electron microscopy we provide evidence that single- and multiple-Staphylococci entrapped undergo cell division. Moreover, the number of WIPI-1 positive autophagosome-like vesicles entrapping Staphylococci significantly increased upon (i) lysosomal inhibition by bafilomycin A1 and (ii) blocking PIKfyve-mediated PtdIns(3,5)P2 generation by YM201636. …”
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126
The role of light in regulating plant growth, development and sugar metabolism: a review
Published 2025-01-01“…Light provides material energy to plants as the basis for cell division and differentiation, chlorophyll synthesis, tissue growth and stomatal movement, and light intensity, photoperiod, and light quality play important roles in these processes. …”
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127
Compilation and functional classification of telomere length-associated genes in humans and other animal species
Published 2023-06-01“…Telomeres are the terminal regions of chromosomes that ensure their stability while cell division. Telomere shortening initiates cellular senescence, which can lead to degeneration and atrophy of tissues, so the process is associated with a reduction in life expectancy and predisposition to a number of diseases. …”
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128
Stimulative Effects of Low Intensity He-Ne Laser Irradiation on the Proliferative Potential and Cell-Cycle Progression of Myoblasts in Culture
Published 2014-01-01“…Meanwhile, the expressions of cell-cycle regulatory proteins in the laser-treated myoblasts were markedly upregulated as compared to the unirradiated cells, indicating that LILI could promote the reentry of quiescent myoblasts into the cell division cycle. These results suggest that LILI at certain fluences could promote their proliferation, thus contributing to the skeletal muscle regeneration following trauma and myopathic diseases.…”
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129
Preparation of Iron Oxide and Titania-Based Composite, Core-Shell Populated, Nanoparticulates Material by Two-Step LASER Ablation in Aqueous Media as Antimicrobial and Anticancer A...
Published 2022-01-01“…The flow cytometry analyses confirmed the NPs’ cytotoxic impacts against the human lung cancer A549 cell lines through the initiation of apoptosis and promotion of the cell cycle arrest at the G1 phase of cell division. To further confirm the cytotoxic effects and the mechanism of the anticancer activity of the synthesized NPs against the A549 cell lines, several related parameters (cell viability, membrane permeability, nuclear intensity, and cytochrome-C release) were analyzed using the high-content screening (HCS) assay. …”
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130
Functional Analysis and Experimental Validation of the Prognostic and Immune Effects of the Oncogenic Protein CDC45 in Breast Cancer
Published 2025-01-01“…Jia-Ning Zhang,1,2,* Lin-Wei Li,1,2,* Man-Qing Cao,1,2,* Xin Liu,1,2 Zi-Lu Yi,1,2 Sha-Sha Liu,1,2 Hong Liu1,2 1The Second Surgical Department of Breast Cancer, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, People’s Republic of China; 2Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong Liu, Email liuhong_submit@tjmuch.comPurpose: Cell division cycle protein 45 (CDC45) plays a crucial role in DNA replication. …”
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131
Identification and characterization of mRNAs of receptor-like kinases MhyGSO1 and MhyGSO2 in flowering parasitic plant Monotropa hypopitys
Published 2017-05-01“…Plant organ formation is based on the balance of the programmed cell division and positional differentiation maintained by intercellular communication mediated by signaling molecules and receptors. …”
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132
Mathematical analysis of steady-state solutions in compartment and continuum models of cell polarization
Published 2011-07-01“…Cell polarization, in which substances previously uniformly distributed become asymmetric due to external or/and internal stimulation, is a fundamental process underlying cell mobility, cell division, and other polarized functions. The yeast cell S. cerevisiae has been a model system to study cell polarization. …”
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133
Cyclin-dependent protein kinases and cell cycle regulation in biology and disease
Published 2025-01-01“…Abstract Cyclin Dependent Kinases (CDKs) are closely connected to the regulation of cell cycle progression, having been first identified as the kinases able to drive cell division. In reality, the human genome contains 20 different CDKs, which can be divided in at least three different sub-family with different functions, mechanisms of regulation, expression patterns and subcellular localization. …”
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134
Comprehensive multi-omics analysis showed that CDC6 is a potential prognostic and immunotherapy biomarker for multiple cancer types including HCC
Published 2025-03-01“…Background: Cell division cycle 6 (CDC6) is a member of the AAA+ ATPase family and has chaperone-like activity. …”
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135
Hydrolyzed Collagen from Salmon Skin Increases the Migration and Filopodia Formation of Skin Keratinocytes by Activation of FAK/Src Pathway
Published 2021-09-01“…Additionally, its molecular mechanism through cell division control protein 42 (Cdc42), Ras-related C3 botulinum toxin substrate 1 (Rac1), and Ras homolog family member A (RhoA) via focal adhesion kinase (FAK)-steroid receptor coactivator (Src) regulation and keratinocyte stem cells (KSCs) markers were also evaluated. …”
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136
Development and experimental validation of dephosphorylation-related biomarkers to assess prognosis and immunotherapeutic response in gliomas
Published 2025-01-01“…The correlation between chemotherapeutic drugs and the half maximal inhibitory concentration (IC50) values of 12 DRGs was analyzed. Cell division cycle 25A (CDC25A) and TMZ were screened and verified by experiments. …”
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137
Evaluation of a strategy for tumor-initiating stem cell eradication in primary human glioblastoma cultures as a model
Published 2018-11-01“…After the treatments, cell division slows down, and the cultures degrade. The K cell line completely degraded within 30 days of observation. …”
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138
Altered cytoskeleton dynamics in patient-derived iPSC-based model of PCDH19 clustering epilepsy
Published 2025-01-01“…Our previous work showed that PCDH19 dysfunction is associated with altered orientation of the mitotic spindle and accelerated neurogenesis, suggesting a contribution of altered cytoskeleton organization in PCDH19-CE pathogenesis in the control of cell division and differentiation. Here, we evaluate the consequences of altered PCDH19 function on microfilaments and microtubules organization, using a disease model obtained from patient-derived induced pluripotent stem cells. …”
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139
Genetic diversity of VIR Raphanus sativus L. collections on aluminum tolerance
Published 2020-10-01“…The accumulation of aluminum in root tissues disrupts the processes of cell division, initiation and growth of the lateral roots, the supply of plants with minerals and water. …”
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140
Integrated bioinformatics analysis identified cuproptosis-related hub gene Mpeg1 as potential biomarker in spinal cord injury
Published 2025-01-01“…Based on ssGSEA, differential expression analysis and WGCNA analysis, we identified two modules that were highly relevant to cell division and immune processes, respectively. From these modules, we identified two hub genes, Cd48 and Mpeg1, which exhibited a strong positive correlation (R = 0.92) and shared similar pathways. …”
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