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Synergistic activity of Pitstop-2 and 1,6-hexanediol in aggressive human lung cancer cells
Published 2025-01-01“…Abstract Metastatic cancer cells undergo metabolic reprogramming, which involves changes in the metabolic fluxes, including endocytosis, nucleocytoplasmic transport, and mitochondrial metabolism, to satisfy their massive demands for energy, cell division, and proliferation compared to normal cells. …”
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82
Non-Canonical, Extralysosomal Activities of Lysosomal Peptidases in Physiological and Pathological Conditions: New Clinical Opportunities for Cancer Therapy
Published 2025-01-01“…Under physiological conditions, lysosomal proteases, through non-canonical, extralysosomal activities, have been linked to cell differentiation, regulation of gene expression, and cell division. Under pathological conditions, these proteases have been linked to cancer, mostly through their extralysosomal activities in the cytosol and nuclei of cells. …”
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83
Phase separation of a microtubule plus-end tracking protein into a fluid fractal network
Published 2025-01-01“…Here, we have study the phase separation of Bik1, a CLIP-170 family member and key +TIP involved in budding yeast cell division. Bik1 is a dimer with a rod-shaped conformation primarily defined by its central coiled-coil domain. …”
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84
Cytomegalovirus Infection and Its Relationship with Leukocyte Telomere Length: A Cross-Sectional Study
Published 2021-01-01“…Telomeres undergo shortening with each cell division, which could be accelerated by infection. …”
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85
Comparison of Real-Time Methods Demonstrating the Effects of Reduced Glutathione on Olfactory Neuroblasts
Published 2025-01-01“…This is the first evidence of a causal link between GSH and changes in cell volume and motility required for cell division, migration, and/or differentiation. Results show the importance of real-time analysis methods, without labelling, in the study of cell responses under culture conditions. …”
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86
RNA Relocation and Persistence of Nucleolus-Like Bodies at Mitosis in Benzo[a]Pyrene-Transformed Human Breast Epithelial Cells after Microcell-Mediated Transfer of Chromosomes 11 a...
Published 2001-01-01“…These results suggest that a normal chromosome 11 but not chromosome 17 contributes to the maintenance of an RNA surplus which accumulates in nucleolus‐like bodies during cell division of the human breast epithelial cells, at least in vitro. …”
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87
De Novo Transcriptome Assembly and Differential Gene Expression Profiling of Three Capra hircus Skin Types during Anagen of the Hair Growth Cycle
Published 2013-01-01“…These genes mainly enriched in the functional cluster associated with cell cycle and cell division. The large contig catalogue as well as the genes which were differentially expressed in different skin types provide valuable candidates for further characterization of gene functions.…”
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88
Comparative gametogenesis and genomic signatures associated with pollen sterility in the seedless mutant of grapevine
Published 2025-02-01“…Conclusion The study showed the downregulation of transcription factors and their target genes involved in cell division, gibberellin biosynthesis and signalling, cell wall development, organization, and pollen germination. …”
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High Efficiency Direct Shoot Organogenesis from Leaf Segments of Aerva lanata (L.) Juss. Ex Schult by Using Thidiazuron
Published 2014-01-01“…Histological observation showed that the epidermal cells of the leaf explants exhibited continuous cell division led to formation of numerous dome shaped meristematic protrusions and subsequently developed into adventitious shoots. …”
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91
Ensemble Deep Learning Object Detection Fusion for Cell Tracking, Mitosis, and Lineage
Published 2024-01-01“…EDNet detections are used in our M2Track multiobject tracking algorithm for tracking cells, detecting cell mitosis (cell division) events, and cell lineage graphs. Our methods produce state-of-the-art performance on the Cell Tracking and Mitosis (CTMCv1) dataset with a Multiple Object Tracking Accuracy (MOTA) score of 50.6% and tracking lineage graph edit (TRA) score of 52.5%. …”
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92
Using Brown Algae in the Plant–Soil System: A Sustainable Approach to Improving the Yield and Quality of Agricultural Crops
Published 2025-01-01“…This type of biostimulants derived from brown algae improve seed germination, increase the accumulation of plant biomass by accelerating cell division and elongation, activating the antioxidant system of plants, making them more resistant to stress, and contributes to the absorption and translocation of nutrients present in the soil. …”
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93
The Unforeseen Diagnosis: Hyperparathyroidism-Jaw Tumour Syndrome Case Report and Review of the Literature
Published 2021-01-01“…Hyperparathyroidism-jaw tumour syndrome is one such autosomal dominant familial disorder, characterised by a mutation in the cell division cycle 73 (CDC73; also known as HRPT-2) tumour suppressor gene. …”
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94
Clinical Features, Treatment, and Surveillance of Hyperparathyroidism-Jaw Tumor Syndrome: An Up-to-Date and Review of the Literature
Published 2019-01-01“…HPT-JT syndrome is caused by germline mutations of the cell division cycle 73 (CDC73) gene that encodes the parafibromin, a 531-amino acid protein with antiproliferative activity. …”
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95
Gene Expression Profiling of the Sciatic Nerve in Streptozotocin-Induced Diabetic Rats with Peripheral Neuropathy
Published 2020-01-01“…DEGs from the 3 most highly connected clusters in the protein-protein interaction network were enriched for biological processes or pathways such as “cell division,” “cell cycle,” “protein phosphorylation,” “chemokine signaling pathway,” “neuropeptide signaling pathway,” “response to drug,” “cellular response to insulin stimulus,” “PPAR signaling pathway,” and “glycerophospholipid metabolism.” …”
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96
CDC25B Is a Prognostic Biomarker Associated With Immune Infiltration and Drug Sensitivity in Hepatocellular Carcinoma
Published 2024-01-01“…Cell division cycle 25B (CDC25B), a member of the CDC25 phosphatase family, plays a key role in cell cycle regulation. …”
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97
NOL-7 serves as a potential prognostic-related biomarker for hepatocellular carcinoma
Published 2025-01-01“…Abstract Background Nucleolar protein 7 (NOL7), a specific protein found in the nucleolus, is crucial for maintaining cell division and proliferation. While the involvement of NOL7 in influencing the unfavorable prognosis of metastatic melanoma has been reported, its significance in predicting the prognosis of patients with Hepatocellular Carcinoma (HCC) remains unclear. …”
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98
Evaluation of Tissue Homogenization to Support the Generation of GMP-Compliant Mesenchymal Stromal Cells from the Umbilical Cord
Published 2016-01-01“…Importantly, kinetic analysis of cultured cells showed logarithmic growth over 10 tested passages, although the rate of cell division was lower for t-H as compared to Col-D. …”
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99
Transcriptomic analysis of Medicago truncatula calli with MtWOX9-1 overexpression
Published 2019-10-01“…It was shown that MtWOX9-1 overexpression led to the activation of several groups of genes, including genes related to cell division, tissue differentiation, and seed development. …”
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100
Antipsychotic Drugs Reverse MK801-Inhibited Cell Migration and F-actin Condensation by Modulating the Rho Signaling Pathway in B35 Cells
Published 2020-01-01“…MK801-induced psychotic symptoms and also the Ras homolog family member A (RhoA) expression and cell division control protein 42 (cdc42) mRNA modulation in the rat brain have been investigated. …”
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