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<i>Helicobacter pylori</i> HP0135 Is a Small Lipoprotein That Has a Role in Outer Membrane Stability
Published 2025-01-01“…The phenotype of the Δ<i>hp0135</i> mutant suggests HP0135 has roles in stabilizing the cell envelope and cell division.…”
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62
The nonlinear cysteine redox dynamics in the i-space: A proteoform-centric theory of redox regulation
Published 2025-04-01“…The post-translational redox regulation of protein function by cysteine oxidation controls diverse biological processes, from cell division to death. However, most current site-centric paradigms fail to capture the nonlinear and emergent nature of redox regulation in proteins with multiple cysteines. …”
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63
The Survivin −31 Snp in Human Colorectal Cancer Correlates with Survivin Splice Variant Expression and Improved Overall Survival
Published 2010-01-01“…Background: Survivin is involved in the regulation of cell division and survival, two key processes in cancer. …”
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64
Origins and Evolution of WUSCHEL-Related Homeobox Protein Family in Plant Kingdom
Published 2014-01-01“…WOX members contain the conserved homeodomain essential for plant development by regulating cell division and differentiation. However, the evolutionary relationship of WOX members in plant kingdom remains to be elucidated. …”
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65
Telomere Biology: Key to unlocking the fountain of youth…A Systematic Review.
Published 2024-11-01“…Deterioration of physiological functions is typically associated with ageing process.This often manifests as various diseases which eventually creates a burden on health infrastructure.Telomere attrition is a phenomenon which involves shortening of telomeres with each cycle of cell division.The phenomenon of “Telomere Attrition” is a “Bi edged sword” as while being a protective shield for the genome on one hand, it also is the cause of many senility related degenerative disorders. …”
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66
Sirtuins, Bioageing, and Cancer
Published 2011-01-01“…Sirtuins are heavily implicated in cell cycle, cell division, transcription regulation, and metabolism, which places the various family members at critical junctures in cellular metabolism. …”
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67
Impact of trainability on telomere dynamics of pet dogs (Canis lupus familiaris): An explorative study in aging dogs.
Published 2025-01-01“…Telomeres, essential for maintaining genomic integrity, undergo shortening with each cell division, leading to cellular senescence. Previous studies in humans have linked cognitive and social factors with telomere dynamics but in animals, such associations remain understudied. …”
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68
Spatio-temporal models of synthetic genetic oscillators
Published 2017-01-01“…Signal transduction pathways play a major role in many important aspects of cellular function e.g. cell division, apoptosis. One important class of signal transduction pathways is gene regulatory networks (GRNs). …”
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69
Understanding cancer from an evolutionary perspective: high-risk reprogramming of genome-damaged stem cells
Published 2024-01-01“…Cells that can overcome senescence can proliferate as defective symmetric cell division, paving the way for malignancy and polyploid giant cancer cell cancers. …”
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70
Single cell suppression profiling of human regulatory T cells
Published 2025-02-01“…To overcome this limitation, we here develop ‘single cell suppression profiling of human Tregs’ (scSPOT). scSPOT uses a 52-marker CyTOF panel, a cell division detection algorithm, and a whole PBMC system to assess the effect of Tregs on all other cell types simultaneously. …”
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71
Microscopic origin of the spatial and temporal precision in biological systems
Published 2025-03-01“…In cell-size regulation, it is argued that a balance between stochastic cell growth and cell division processes leads to a narrow distribution of cell sizes. …”
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72
Dietary Ganglioside Reduces Proinflammatory Signaling in the Intestine
Published 2012-01-01“…Ganglioside composition of the intestinal brush border and apical surface of the colon influences numerous cell processes including microbial attachment, cell division, differentiation, and signaling. Accelerated catabolism of ganglioside in intestinal disease results in increased proinflammatory signaling. …”
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73
The enigma of cancer polyploidy as deciphered by evolutionary cancer cell biology (ECCB)
Published 2024-06-01“…The cells lose their stemness and differentiation potential but persist in proliferation as low-grade polyploids (4n) through defective symmetric cell division (DSCD). Genomic integrity can be restored through homotypic cell and nuclear fusion, resulting in the formation of high-grade polyploids known as multinucleated genome repair syncytia, or by inductive hyperpolyploidization of more than 64n, as observed in single-celled polyploid giant cancer cells. …”
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74
The Possible Crystallization Process in the Origin of Bacteria, Archaea, Viruses, and Mobile Elements
Published 2024-12-01“…Bilayer lipid membrane formation, proto-cell formation with a permeable membrane, proto-cell division, and the evolution of membrane-associated biochemistry are presented in detail. …”
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75
Short Telomere Length in Plasma of Sudanese Patients with Hepatocellular Carcinoma and Chronic Liver Diseases
Published 2024-12-01“… Background: Telomeres, a protective sequence of DNA at the end of chromosomes, are essential for the maintenance of chromosomal integrity and stability. With each cell division, telomeres are shortened until a critical length is reached. …”
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76
Cellular senescence-associated genes in rheumatoid arthritis: Identification and functional analysis.
Published 2025-01-01“…Cellular senescence, a hallmark of aging marked by a permanent halt in cell division due to damage and stress, is crucial in aging and related diseases. …”
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77
CDCA7 enhances STAT3 transcriptional activity to regulate aerobic glycolysis and promote pancreatic cancer progression and gemcitabine resistance
Published 2025-02-01“…Abstract Cell division cycle associated 7 (CDCA7) plays a role in various malignancies, especially pancreatic cancer (PC). …”
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78
Modification of the telomerase gene with human regulatory sequences resets mouse telomeres to human length
Published 2025-02-01“…Abstract Telomeres shorten with each cell division, serving as biomarkers of aging, with human tissues exhibiting short telomeres and restricted telomerase expression. …”
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79
Acute Putrescine Supplementation with Schwann Cell Implantation Improves Sensory and Serotonergic Axon Growth and Functional Recovery in Spinal Cord Injured Rats
Published 2015-01-01“…Polyamines are ubiquitous organic cations that play an important role in the regulation of the cell cycle, cell division, cytoskeletal organization, and cell differentiation. …”
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80
Traumatic Brain Injury Promotes Neurogenesis and Oligodendrogenesis in Subcortical Brain Regions of Mice
Published 2025-01-01“…Here, we investigated cell division and differentiation in non-neurogenic brain regions during the acute and delayed phases of TBI-induced neurodegeneration. …”
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