Mathematical Analysis Of A Modular Network Coordinating The Cell Cycle And Apoptosis by Gheorghe Craciun, Baltazar Aguda, Avner Friedman

“…The cell-division cycle and apoptosis are key cellular processes deregulated during carcinogenesis. …”
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Generation of Induced Pluripotent Stem (iPS) Cells by Nuclear Reprogramming by Dilip Dey, Gregory R. D. Evans

“…During embryonic development pluripotency is progressively lost irreversibly by cell division, differentiation, migration and organ formation. …”
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L-Ascorbic Acid: A Multifunctional Molecule Supporting Plant Growth and Development by Daniel R. Gallie

“…Ascorbic acid regulates cell division and growth and is involved in signal transduction. …”
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N.R. Ayupova by N.R. Ayupova

“…The structures of fossil bacteria based on their size, shape, cell division, distribution in colonies and comparison with ferruginous sediments of modern hydrothermal systems and massive sulfide deposits worldwide indicate that they correspond to mineralized stalks of iron bacteria Leptothrix ochracea and Gallionella ferruginea, coccoidal forms and sulfur-oxidizing Thiobacillus Ferrooxidans and giant Beggiatoa-like organisms. …”
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An integrated cellular and sub-cellular model of cancer chemotherapy and therapies that target cell survival by Alexis B. Cook, Daniel R. Ziazadeh, Jianfeng Lu, Trachette L. Jackson

“…Apoptosis resistance is a hallmark of human cancer, and tumor cells often become resistant due to defects in the programmed cell death machinery.Targeting key apoptosis regulators to overcome apoptotic resistance and promote rapid death of tumor cells is an exciting new strategy for cancer treatment, either alone or in combination with traditionally used anti-cancer drugs that target cell division. Here we present a multiscale modeling framework for investigating the synergism between traditional chemotherapy and targeted therapies aimed at critical regulators of apoptosis.…”
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Aneuploidy Mechanisms in Human Colorectal Preneoplastic Lesions and Barrett’s Esophagus. Is There a Role for K-Ras and p53 Mutations? by Walter Giaretti

“…These data and data from experiments using in vitro and mouse models, suggest that chromosome instability, tetraploidization, and asymmetrical chromosome segregation during cell division are the result of deregulated cell cycle genes with multiple functions that normally exert active checks on the cell cycle processes including apoptosis and chromosome stability.…”
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Artemisinin-Based Combination Therapy Depressed Mitosis and Induced Chromosome Aberration in Onion Root Cells by J. I. Raji, C. K. Onwuamah, P. G. C. Odeigah

“…Their accumulation in cells may be inhibitory to cell division and growth. This calls for caution in the administration of artemisinin combination therapy for the treatment of malaria ailment. …”
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Tennis Rehabilitation Training-Assisted Paclitaxel Nanoparticles in Treatment of Lung Tumor by Di Hu, YiMin Yang

“…Its mechanism of action is to prevent tumor rupture by stabilizing tumor proteins, while preventing cell division, leading to cell death, thereby inhibiting the spread of lung tumors. …”
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COMPARATIVE ANALYSIS OF THE FREQUENCY OF CYTOGENETIC ABNORMALIES IN THE ROOT APICAL MERISTEM OF SPRING BARLEY (<i>HORDEUM VULGARE </i> L.) CULTIVAE SEEDLINGS, CONTRASTING IN THEIR... by A. V. Dikarev, V. G. Dikarev, N. S. Dikareva

“…Cell division activity, frequencies and spectra of cytogenetical abnormalities were studied in the root apical meristem cells of spring barley seedlings (Hordeum vulgare L.). …”
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Molecular profiling and detection methods of microRNA in cancer research by Nurul-Syakima Ab Mutalib, Imilia Ismail, Hooi-Leng Ser

“…Years after that, researchers then realized that these miRNAs are actually important regulatory molecules — controlling cell division signaling, apoptosis and so on. In fact, the unusual expression of miRNAs has also been associated in etiology of various cancers. …”
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Making the Final Cut — Mechanisms Mediating the Abscission Step of Cytokinesis by John A. Schiel, Rytis Prekeris

“…Cytokinesis is the final stage of mitotic cell division that results in a physical separation of two daughter cells. …”
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Effects of elongation delay in transcription dynamics by Xuan Zhang, Huiqin Jin, Zhuoqin Yang, Jinzhi Lei

“…This paper studies the transcription dynamics that involved the elongation delay and effects of cell division and DNA replication. The stochastic process of gene expression is modeled with delay chemical master equation with periodic coefficients, and is studied numerically through the stochastic simulation algorithm with delay. …”
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Incomplete divisions between sister germline cells require Usp8 function by Mathieu, Juliette, Huynh, Jean-René

“…Cytokinetic abscission is the final step of cell division, resulting in two separate daughter cells. …”
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Mitochondrial abnormalities as a target of intervention in acute myeloid leukemia by Elissa Tjahjono, Megan R. Daneman, Bernadetta Meika, Alexey V. Revtovich, Natalia V. Kirienko

“…On one hand, it provides a source of building blocks for further cell division and serves as a method for removing damaged organelles, promoting cell survival. …”
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Reaction-Diffusion on a Spatial Mathematical Model of Cancer Immunotherapy with Effector Cells and IL-2 Compounds’ Interactions by Sulasri Suddin, Fajar Adi-Kusumo, Lina Aryati, Gunardi

“…., p53 and pRb, from controlling the activation of the cell division and the cell apoptosis. In this paper, we consider the interactions among the cancer cell population, the effector cell population that is a part of the immune system, and cytokines that can be used to stimulate the effector cells called the IL-2 compounds. …”
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Targeting the G-quadruplex as a novel strategy for developing antibiotics against hypervirulent drug-resistant Staphylococcus aureus by Maria Sultan, Maria Razzaq, Joohyun Lee, Shreyasi Das, Shrute Kannappan, Vinod Kumar Subramani, Wanki Yoo, Truc Kim, Hye-Ra Lee, Akhilesh K. Chaurasia, Kyeong Kyu Kim

“…NMM exhibited a minimum inhibitory concentration (MIC) of 5 μM against S. aureus USA300, impacting cell division and the cell wall by repressing the expressions of genes in the division cell wall (dcw) gene cluster. …”
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Evolutionary plasticity and functional repurposing of the essential metabolic enzyme MoeA by Daniela Megrian, Mariano Martinez, Pedro M. Alzari, Anne Marie Wehenkel

“…We recently discovered that Actinobacteria have a repurposed version of MoeA (Glp) linked to bacterial cell division. Since MoeA exists in all domains of life, our study explores how it gained multifunctionality over time. …”
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Carcinogenesis and Chemotherapy Viewed from the Perspective of Stoichiometric Network Analysis (SNA): What Can the Biological System of the Elements Contribute to an Understanding... by Stefan Franzle, Bernd Markert

“…The essential role of autocatalysis in biology and the drawbacks of either controlled or spontaneous cell division can be used to understand crucial aspects of carcinogenesis and chemotherapy because SNA describes and predicts effects of autocatalysis, including phase effects that may be due to some kind of intervention. …”
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Mitotic Kinases and p53 Signaling by Geun-Hyoung Ha, Eun-Kyoung Yim Breuer

“…Deregulation of mitotic kinases is significantly associated with improper cell division and aneuploidy. Because of their importance during mitosis and the relevance to cancer, mitotic kinase signaling has been extensively studied over the past few decades and, as a result, several mitotic kinase inhibitors have been developed. …”
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Clinical isolates of Candida auris with enhanced adherence and biofilm formation due to genomic amplification of ALS4. by Jian Bing, Zhangyue Guan, Tianhong Zheng, Zhijie Zhang, Shuru Fan, Craig L Ennis, Clarissa J Nobile, Guanghua Huang

“…A unique morphological feature of this fungus is its multicellular aggregating phenotype, which has been thought to be associated with defects in cell division. In this study, we report a new aggregating form of two clinical C. auris isolates with increased biofilm forming capacity due to enhanced adherence of adjacent cells and surfaces. …”
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