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hnRNPA2/B1 Ameliorates LPS-Induced Endothelial Injury through NF-κB Pathway and VE-Cadherin/β-Catenin Signaling Modulation In Vitro
Published 2020-01-01“…Heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2/B1) is a protein involved in the regulation of RNA processing, cell metabolism, migration, proliferation, and apoptosis. …”
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62
DIA-based quantitative proteomic analysis on porcine meat quality at different chilling rates
Published 2024-09-01“…These pathways indicated that VFC delayed cell metabolism and glycolysis by down-regulating the expression of metabolic enzymes. …”
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63
The Effect of Blood-Derived Products on the Chondrogenic and Osteogenic Differentiation Potential of Adipose-Derived Mesenchymal Stem Cells Originated from Three Different Location...
Published 2019-01-01“…Blood products enhance ex vivo cell metabolism. Chondrogenesis is enhanced by EDTA-PRP and osteogenesis by citrate PRP, whereas hyperacute serum enhances both differentiations comparably. …”
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64
Exploring the Potential of SGLT-2 Inhibitors in Cancer Treatment: Mechanisms, Preclinical Findings, and Clinical Implications
Published 2025-01-01“…Description of the state of knowledge Preclinical studies suggest that SGLT-2 inhibitors can alter cancer cell metabolism by limiting glucose availability, potentially impeding tumor growth. …”
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65
Metabolic reprogramming and macrophage expansion define ACPA-negative rheumatoid arthritis: insights from single-cell RNA sequencing
Published 2025-01-01“…By integrating single-cell RNA sequencing with machine learning, this study established a neural network model that robustly differentiates patients with ACPA− RA from healthy controls, highlighting promising diagnostic biomarkers and therapeutic targets centered on immune cell metabolism.…”
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66
Effects of olive leaf extract on exercise performance and muscle mitochondrial response in young healthy adults
Published 2025-01-01“…Mitochondrial calcium uptake declines during aging and is directly activated by oleuropein to boost energy metabolism and skeletal muscle performance. Cell Metabolism. https://doi.org/10.1016/j.cmet.2024.10.021 …”
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67
TGFβ1 Restores Energy Homeostasis of Human Trophoblast Cells Under Hyperglycemia In Vitro by Inducing PPARγ Expression, AMPK Activation, and HIF1α Degradation
Published 2025-01-01“…The TGFβ1/SMAD2 signaling pathway and the transcription factors PPARγ, HIF1α, and AMPK are key regulators of cell metabolism and are known to play critical roles in extravillous trophoblast cell differentiation and function. …”
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68
Hubungan Kadar FT4 dan TSH Serum dengan Profil Lipid Darah pada Pasien Hipertiroid yang Dirawat Inap di RSUP Dr. M. Djamil Padang Tahun 2009 - 2013
Published 2014-01-01“…It has spesific effects on cell metabolism, including lipid metabolism.L ipid metabolism disorder in hyperthyroid will inflict clinical manifestation; such as mood disorders, depression, and increased aggressive behavior. …”
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69
Inverse Agonist of Retinoid-Related Orphan Receptor-Alpha Prevents Apoptosis and Degeneration in Nucleus Pulposus Cells via Upregulation of YAP
Published 2021-01-01“…Therefore, we applicated a well-established inverse agonist of RORα, SR3335, to investigate its role in regulating NP cell metabolism and apoptosis. To further investigate the mechanism that SR3335 regulates the pathogenesis of IDD in vitro, tumor necrosis factor alpha (TNF-α) stimulation was used in human NP cells to mimic the hostile environment that leads to degeneration. …”
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70
Positron emission tomography for phenotyping inflammation of cardiovascular diseases
Published 2024-12-01“…This review summarizes the PET imaging of key immune cell responses in CVDs, including immune cell metabolism, ligand/receptor interactions, and enzyme secretion, and discusses emerging opportunities and challenges in PET imaging-based inflammatory phenotyping and future perspectives.…”
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71
Hemolymph microbiota and immune effectors’ expressions driven by geographical rearing acclimation of the aquacultured Penaeus stylirostris
Published 2025-01-01“…Putative microbial functions were mostly associated with bacterial competition, infections and metabolism in NC, while they were highly associated with the cell metabolism in FP suggesting a rearing site discrimination. …”
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72
PRMT5 promotes ovarian cancer growth through enhancing Warburg effect by methylating ENO1
Published 2023-04-01“…However, the exactly roles and underlying mechanisms of PRMT5 contributing to the progression of ovarian cancer mediated by reprogramming cell metabolism remain largely elusive. Here, we report that PRMT5 is highly expressed and correlates with poor survival in ovarian cancer. …”
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73
Identification of Host–Protein Interaction Network of Canine Parvovirus Capsid Protein VP2 in F81 Cells
Published 2025-01-01“…The results showed that CPV VP2 protein participated mainly in cell metabolism, cell biosynthesis, protein folding and various signal transduction processes. …”
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74
Targeting SRSF1 improves cancer immunotherapy by dually acting on CD8+T and tumor cells
Published 2025-01-01“…We therefore introduce a paradigm targeting SRSF1 that simultaneously disrupts tumor cell metabolism and enhances the antitumor immunity of CD8+ T cells.…”
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75
Brain Plasticity and Cell Competition: Immediate Early Genes Are the Focus
Published 2025-01-01“…In addition, IEGs are involved in the regulation of brain cells’ metabolism, proliferation, and survival, in the establishment of multicellular ensembles, and, presumably, in cell competition in the tissue. …”
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76
MVK, induced by Kras, represses cGAS-Sting signalling in lung adenocarcinoma
Published 2025-01-01“…Abstract Cholesterol metabolism is abnormally active in tumour cells. Metabolic enzymes related to cholesterol metabolism are upregulated in tumours, but their nonmetabolic functions remain unclear. …”
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77
Lipid metabolism in myeloid cell function and chronic inflammatory diseases
Published 2025-01-01“…Recent studies have elucidated that during immune cell metabolic reprogramming, lipid metabolism, including lipid uptake, de novo lipid synthesis and fatty acid oxidation, undergoes significant alteration, resulting in dynamic changes in the quantity and quality of intracellular lipids. …”
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78
Nutrition and Reproductive Health: Sperm versus Erythrocyte Lipidomic Profile and ω-3 Intake
Published 2015-01-01“…Molecular diagnostic tools are necessary to understand the cell metabolic turnover and monitor the success of nutraceuticals for personalized treatments.…”
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79
Antibacterial mechanism of Lactiplantibacillus plantarum SHY96 cell-free supernatant against Listeria monocytogenes revealed by metabolomics and potential application on chicken br...
Published 2025-01-01“…This study demonstrated that the cell-free supernatant of L. plantarum SHY96 (LCFS96) effectively inhibits the growth and biofilm formation of L. monocytogenes CMCC(B)54002 (L. monocytogenes_02) by reducing cell metabolic activity and damaging cell structure. Metabolomic analysis revealed that LCFS96 significantly altered 450 intracellular metabolites, affecting key metabolic pathways including linoleic acid metabolism, pyrimidine metabolism, purine metabolism, pantothenic acid and CoA biosynthesis, and the TCA cycle. …”
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80
miR-142 deficit in T cells during blast crisis promotes chronic myeloid leukemia immune escape
Published 2025-02-01“…In CML murine models, miR-142 deficit impairs thymic differentiation of lymphoid-primed multipotent progenitors (LMPP) into T cells and prevents T cells’ metabolic reprogramming, thereby leading to loss of T cells and leukemia immune escape. …”
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