Three-dimensional structure of entire hydrated murine hearts at histological resolution by Jasper Frohn, Frederik Böddeker, Marius Reichardt, Hendrik Bruns, Titus Czajka, Amara Khan, Ludovic Broche, Michael Krisch, Alberto Bravin, Frauke Alves, Jana Zschüntzsch, Tim Salditt

“…The different cardiovascular disease models are analysed based on metrics derived from the 3d structure tensor. …”
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The Prognostic Significance of Sleep and Circadian Rhythm for Myocardial Infarction Outcomes: Case-Control Study by Wei-Chih Chin, Pao-Hsien Chu, Lung-Sheng Wu, Kuang-Tso Lee, Chen Lin, Chien-Te Ho, Wei-Sheng Yang, I-Hang Chung, Yu-Shu Huang

“…Most previous studies assessed the premorbid sleep and circadian rhythm of patients with MI and their correlations with cardiovascular disease. However, little is known about post-MI sleep and circadian rhythm and their impacts on prognosis. …”
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Early Subclinical Atherosclerosis in Gestational Diabetes: The Predictive Role of Routine Biomarkers and Nutrigenetic Variants by Marica Franzago, Federica Fraticelli, Marta Di Nicola, Francesco Bianco, Daniela Marchetti, Claudio Celentano, Marco Liberati, Raffaele De Caterina, Liborio Stuppia, Ester Vitacolonna

“…Gestational diabetes mellitus (GDM) can be considered a silent risk for out-of-pregnancy diabetes mellitus (DM) and cardiovascular disease (CVD) later in life. We aimed to assess the predictive role of 3rd trimester lipid profile during pregnancy for the susceptibility to markers of subclinical atherosclerosis (CVD susceptibility) at 3 years in a cohort of women with history of GDM. …”
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Cardiovascular risk profiling among South Asian adults in Hong Kong: a latent class analysis by Gary Ka-Ki Chung, Woohyung Lee, Danna Camille Vargas, Bulbul Sharma, Kai Sing Sun, Heidi Hung, Lee Sha Tong, Tsz Lui Tang, Hasiba Munir, Chi Yui Wong, Soniya Pun, Man Hin Chio, Eliza Lai-Yi Wong, Dong Dong, Eng-Kiong Yeoh

“…The heavy burden on obesity especially in women, lifestyle and psychological risks especially in men, and low overall physical activity level may be translated into a tremendous cardiovascular disease burden in the forthcoming decades, in particular among Pakistani and Nepalese as well as the socioeconomically disadvantaged.…”
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Contribution of type 2 diabetes to major adverse cardiovascular events (MACE) in a long-term observational study with different stages of atherosclerosis by Arthur Mader, Dario Haeberli, Barbara Larcher, Jörn F. Dopheide, Christoph H. Saely, Christine F. Heinzle, Peter Amann, Marc Schindewolf, Andreas Festa, Heinz Drexel

“…Abstract The impact of diabetes on incident cardiovascular disease in relation to the extent of atherosclerotic disease remains unclear. …”
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Deep-learning prediction of cardiovascular outcomes from routine retinal images in individuals with type 2 diabetes by Mohammad Ghouse Syed, Emanuele Trucco, Muthu R. K. Mookiah, Chim C. Lang, Rory J. McCrimmon, Colin N. A. Palmer, Ewan R. Pearson, Alex S. F. Doney, Ify R. Mordi

“…Abstract Background Prior studies have demonstrated an association between retinal vascular features and cardiovascular disease (CVD), however most studies have only evaluated a few simple parameters at a time. …”
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The potential impact of glycine supplementation on the process of aging by Michalina Wójcikiewicz, Julia Kulbacka, Witold Czyż, Julia Kacperczyk, Karol Dziedzic, Marta Chuncia-Ileczko, Maciej Wojszczyk, Damian Zys, Piotr Pasek, Julia Ryniecka, Wiktor Czaja, Michał Krzciuk

“…These changes increase vulnerability to age-related disorders, including cardiovascular disease, neurodegenerative conditions, metabolic syndrome, and frailty. …”
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A review of the research progress on nursing measures in cardiac rehabilitation with integrated Chinese and western medicine (中西医结合心脏康复护理研究进展) by ZHANG Wenjuan (张文娟), TIAN Hongyan (田洪燕), GEN Ao (耿敖), XU Xiao (徐笑), ZHANG Xuan (张璇), YU Meili (于美丽), YUE Zong (岳宗), CHEN Liang (陈亮)

“…The incidence of cardiovascular disease in China is still showing an increasing trend year by year. …”
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Supplementation with Standardized Green/Black or White Tea Extracts Attenuates Hypertension and Ischemia-Reperfusion-Induced Myocardial Damage in Mice Infused with Angiotensin II by Mario de la Fuente-Muñoz, Marta Román-Carmena, Sara Amor, María C. Iglesias-de la Cruz, Patricia Martorell, Sonia Guilera-Bermell, Reme García Bou, Antonio M. Inarejos-García, Ángel L. García-Villalón, Miriam Granado

“…Arterial hypertension has a high prevalence in the population and is considered both a cardiovascular disease and an important risk factor for the development of other cardiovascular diseases. …”
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Diagnosis and management of type 2 diabetes mellitus in patients with ischaemic heart disease and acute coronary syndromes - a review of evidence and recommendations by Muhammad Usman Shah, Muhammad Usman Shah, Alun Roebuck, Bala Srinivasan, Joanna Kate Ward, Paul Edward Squires, Claire Elizabeth Hills, Kelvin Lee, Kelvin Lee

“…These account accounting for 50% of deaths in patients with T2DM. Cardiovascular diseases in the context of diabetes particular represent a significant cause of morbidity and mortality with a two to three times higher risk of cardiovascular disease in individuals with T2DM than in those without the condition normo-glycaemia. …”
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The Correlation of Serum Adropin with Cardiovascular Risk Factors in the Experimental Rat Model of Chronic Kidney Disease and Its Implication in the Ameliorative Effect of Angioten... by Samaa Salah Abd-El-Fatah, Maha A. Fathy, Mohamed Ali Alabiad, Raja Aljafil, Mai Ahmed Gobran, Enssaf A. Ahmad, Ashwag S. Alsharidah, Mohammed Alorini, Sulaiman Mohammed Alnasser, Sara A. Awadh, Enas N. Morgan

“…Background: The risk of cardiovascular disease (CVD) in patients with chronic kidney disease (CKD) is estimated to be far greater than that in the general population. …”
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Mast Cells Positive to Tryptase and c-Kit Receptor Expressing Cells Correlates with Angiogenesis in Gastric Cancer Patients Surgically Treated by Michele Ammendola, Rosario Sacco, Giuseppe Sammarco, Giuseppe Donato, Valeria Zuccalà, Roberto Romano, Maria Luposella, Rosa Patruno, Carlo Vallicelli, Giorgio Maria Verdecchia, Davide Cavaliere, Severino Montemurro, Girolamo Ranieri

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Promotional tone in reviews of menopausal hormone therapy after the Women's Health Initiative: an analysis of published articles. by Adriane Fugh-Berman, Christina Pike McDonald, Alicia M Bell, Emily Catherine Bethards, Anthony R Scialli

“…Scientific accuracy was assessed based on whether or not the findings of the WHI were accurately reported using two criteria: (1) Acknowledgment or lack of denial of the risk of breast cancer diagnosis associated with hormone therapy, and (2) acknowledgment that hormone therapy did not benefit cardiovascular disease endpoints. Determination of promotional tone was based on the assessment by each reader of whether the article appeared to promote hormone therapy. …”
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The Effects of Statin Dose, Lipophilicity, and Combination of Statins plus Ezetimibe on Circulating Oxidized Low-Density Lipoprotein Levels: A Systematic Review and Meta-Analysis o... by Tannaz Jamialahmadi, Fatemeh Baratzadeh, Željko Reiner, Luis E. Simental-Mendía, Suowen Xu, Andrey V. Susekov, Raul D. Santos, Amirhossein Sahebkar

“…Elevated plasma low-density lipoprotein cholesterol (LDL-C) is the main risk factor for atherosclerotic cardiovascular disease (ASCVD). Statins are the drugs of choice for decreasing LDL-C and are used for the prevention and management of ASCVD. …”
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Cardiovascular risk factors and markers of myocardial injury and inflammation in people living with HIV in Nairobi, Kenya: a pilot cross-sectional study by Pablo Perel, Kuan Ken Lee, Anoop SV Shah, Mohammed K Ali, Shirjel R Alam, Jasmit Shah, Hassan Adan Ahmed, Jeilan Mohamed, Isaiah G Akuku, Sherry Eskander, Michael H Chung

“…Objectives To determine the prevalence of cardiovascular disease (CVD) risk factors and explore associations with high-sensitivity cardiac troponin I (hscTnI) and high-sensitivity C-reactive protein (hsCRP) in people living with HIV (PLHIV) in Kenya.Design Pilot cross-sectional study.Setting Data were collected from community HIV clinics across two sites in Nairobi, Kenya, from July 2019 to May 2020.Participants Convenience sample of 200 PLHIV (≥30 years with no prior history of CVD).Outcome measures Prevalence of cardiovascular risk factors and its association with hsTnI and hsCRP levels.Results Across 200 PLHIV (median age 46 years, IQR 38–53; 61% women), the prevalence of hypercholesterolaemia (total cholesterol >6.1 mmol/L) and hypertension were 19% (n=30/199) and 30% (n=60/200), respectively. …”
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Smart phone-based transcutaneous electrical acupoint stimulation as adjunctive therapy for hypertension (STAT-H trial): protocol for a cluster randomised controlled trial by Yu Wang, Xiao Wang, Ying Lin, Chao-Qun Yan, Guang-Xia Shi, Cun-Zhi Liu, Jing-Wen Yang, Jian-Feng Tu, Shi-Yan Yan, Xin-Tong Su, Li-Qiong Wang, Si-Bo Kang, Bao-Hong Mi, He-Wen Li, Xue-Zhou Wang

“…Introduction Hypertension is a common risk factor for cardiovascular disease. Transcutaneous electrical acupoint stimulation (TEAS) may be effective for hypertension, but the evidence remains limited. …”
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D-mannose alleviates chronic periodontitis in rats by regulating the functions of neutrophils by Xue Li, Xueting Chen, Qingyu Zhu, Pengye Zhang, Shunxue Nan, Lei Lv, Shengcai Qi

“…It significantly impacts oral health and has been linked to systemic conditions like cardiovascular disease and diabetes. The critical role of neutrophils in the occurrence and development of chronic periodontitis has been paid increasing attention. …”
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Rationale and design of APOLLO: a personalized rehAbilitation PrOgram in aLLOgeneic bone marrow transplantation by Edith Pituskin, Stephen Foulkes, Rachel J. Skow, Thomas McMurtry, Calvin Kruger, Janet E. Bates, Daena Lamoureux, Joseph Brandwein, Elena Lieuw, Cynthia Wu, Nancy Zhu, Peng Wang, Daniel Sawler, Minakshi Taparia, Marlene Hamilton, Tiffany Comfort-Riddle, Tara Meyer, Gabor T. Gyenes, Ian Paterson, Carla M. Prado, Mark J. Haykowsky, Justin G. Greiner, Margaret L. McNeely, Puneeta Tandon, Richard B. Thompson

“…Despite modern treatment regimens and support, cardiovascular disease remains a leading cause of non-relapse mortality among allo-BMT survivors. …”
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Relationship of serum total cholesterol and triglyceride with risk of mortality in maintenance hemodialysis patients: a multicenter prospective cohort study by Yan Huang, Qiuxia Zhong, Junzhi Chen, Xianhui Qin, Yaya Yang, Yanhuan He, Zizhen Lin, Yumin Li, Shenglin Yang, Yongxin Lu, Yanhong Zhao, Yaozhong Kong, Qijun Wan, Qi Wang, Sheng Huang, Yan Liu, Aiqun Liu, Fanna Liu, Fanfan Hou, Min Liang

“…The primary outcome was all-cause mortality and secondary outcome was cardiovascular disease (CVD) mortality.Results During a median follow-up duration of 4.4 years (IQR= 2.0–7.9 years), 549 (53.0%) patients died, and 297 (28.7%) deaths were attributed to CVD. …”
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The predictive role of the hs-CRP/HDL-C ratio for long-term mortality in the general population: evidence from a cohort study by Yifeng Wang, Li Wang, Zongquan Zhao, Song Yin, Xuejun Tang, Kerui Zhang

“…Abstract Background The high-sensitivity C-reactive protein (hs-CRP) to high-density lipoprotein cholesterol (HDL-C) ratio, a composite marker of low-grade inflammation and lipid metabolism, is reportedly associated with the occurrence of new cardiovascular diseases (CVDs) in certain people. However, the predictive value of the hs-CRP/HDL-C ratio for long-term mortality in the general population remains unclear. …”
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