In-depth proteomic profiling identifies potentiation of the LPS response by 7-ketocholesterol by Iain R. Phair, Magdalena Sovakova, Noor Alqurashi, Raid B. Nisr, Alison D. McNeilly, Douglas Lamont, Graham Rena

“…Earlier findings from CANTOS and the recent FDA approval of colchicine highlight that inflammation is a viable target for cardiovascular disease; however, it is currrently unclear which will be the best anti-inflammatory targets to pursue in the future. …”
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Evaluation of the role of hydroxychloroquine as a lipid profile improving and glucose adjusting drug in Egyptian females with inactive rheumatoid arthritis by Aliaa O. El-Hady, Mai M. Kamel, Yasmin T. Mosaad, Maha A. Ali, Soad S. El Molla

“…Background/aim Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease that leads to joint destruction and disability with increased risk of cardiovascular disease (CVD), a leading cause of morbidity and mortality in RA. …”
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Co-occurrence of behavioural risk factors for non-communicable diseases and mortality risk in Spain: a population-based cohort study by Iñaki Galán, Cristina Ortiz, Carmen Rodriguez-Blazquez, Teresa López-Cuadrado, Ana Ayuso-Álvarez

“…Those reporting five risk factors had SRRs of 6.35 (95% CI 2.91; 13.83) and 2.57 (95% CI 1.11; 5.98) for tumour-related and cardiovascular disease mortality, respectively.Conclusions The co-occurrence of unhealthy behaviours increases the risk of overall and cause-specific mortality. …”
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Vital signs-based healthcare kiosks for screening chronic and infectious diseases: a systematic review by Saksham Bhutani, Aymen Alian, Richard Ribon Fletcher, Hagen Bomberg, Urs Eichenberger, Carlo Menon, Mohamed Elgendi

“…Furthermore, cardiovascular disease detection emerges as the primary motivation in 56% of the included studies. …”
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Predicted quality benefits of achievable performance benchmarks of chronic heart failure care in China: results from a nationwide observational study by Xi Li, Chao Wang, Jingkun Li, Yupeng Wang, Xiaoqiang Bao, Meina Liu, Qiuju Zhang, Chang Yin, Xudong Ma

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Methylenetetrahydrofolate reductase gene polymorphisms, lipid profiles, and basic renal functional markers as risk for myocardial infarction: A case-control study and haplotype ana... by Perović Svetlana, Vujović Slavica, Kapur-Pojskić Lejla, Garai Nemanja, Šćepanović Anđelka

“…Myocardial infarction (MI) is a serious cardiovascular disease and the primary cause of mortality, with a complex etiopathology. …”
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Associations between heavy metal exposure and vascular age: a large cross-sectional study by Yuntao Feng, Chengxing Liu, Litang Huang, Jun Qian, Na Li, Hongwei Tan, Xuebo Liu

“…Abstract Background Heavy metal exposure is an emerging environmental risk factor linked to cardiovascular disease (CVD) through its effects on vascular ageing. …”
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Mechanisms of Copper-Induced Autophagy and Links with Human Diseases by Yuanyuan Fu, Shuyan Zeng, Zhenlin Wang, Huiting Huang, Xin Zhao, Min Li

“…Recently, the potential therapeutic role of copper-induced autophagy in chronic diseases such as Parkinson’s, Wilson’s, and cardiovascular disease has already been demonstrated. In brief, copper ions, numerous copper complexes, and copper-based nano-preparations could induce autophagy, a lysosome-dependent process that plays an important role in various human diseases. …”
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The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients by Kai Liu, Shu Liu, Ting-ting Xu, Hong Qiao

“…Common comorbidities in the diabetic group were hypertension, cerebrovascular disease, chronic kidney disease and cardiovascular disease. We discovered that white blood cell count, neutrophil count, inflammatory marker levels, D-dimer, urea, precursor of the brain natriuretic peptide (Pro-BNP) increased and lymphocyte count, estimated glomerular filtration rate (eGFR), albumin decreased significantly in the diabetic group in laboratory test results. …”
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Serum galectin-3 and fibroblast growth factor-23 levels in relation with type 2 diabetes and cardiovascular risk by Klisic Aleksandra, Gluscevic Sanja, Karakasis Paschalis, Kotur-Stevuljevic Jelena, Ninic Ana

“…Hence, the aim of this research was to explore galectin-3 and FGF-23 in relation to T2D, as well as to examine the potential association of these biomarkers with atherosclerotic cardiovascular disease (ASCVD) risk score in Montenegrin adults. …”
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Diagnosis and Treatment of Elderly and Senile Chronic Constipation: an Expert Consensus by V. T. Ivashkin, M. G. Mnatsakanyan, V. S. Ostapenko, А. P. Pogromov, V. M. Nekoval, E. A. Poluectova, Yu. V. Kotovskaya, N. K. Runikhina, N. V. Sharashkina, P. V. Tsarkov, N. O. Tkacheva, Yu. N. Belenkov

“…Chronic constipation is associated with a higher risk of cardiovascular disease and complications, impaired general perception of health and pain, growing alarm and depression, and reduced quality of life. …”
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M2 Macrophages as a Potential Target for Antiatherosclerosis Treatment by Ying Bi, Jixiang Chen, Feng Hu, Jing Liu, Man Li, Lei Zhao

“…Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of mortality worldwide. …”
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Effect of Repetitive Glucose Spike and Hypoglycaemia on Atherosclerosis and Death Rate in Apo E-Deficient Mice by Kenichi Nakajima, Tomoya Mita, Yusuke Osonoi, Kosuke Azuma, Toshiyuki Takasu, Yoshio Fujitani, Hirotaka Watada

“…Epidemiological data suggest that postprandial hyperglycaemia and hypoglycaemia are potential risk factors for cardiovascular disease. However, the effects of repetitive postprandial glucose spikes, repetitive hypoglycaemia, and their combination on the progression of atherosclerosis remain largely unknown. …”
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Ultra-processed food intake, genetic polymorphisms, and the risk of dyslipidemia in the adult Korean population by Minsu Cho, Heejin Lee, Jung Eun Lee

“…Participants: 20,044 Korean adults aged ≥40 years in the Health Examinees (HEXA) study, the Cardiovascular Disease Association Study (CAVAS), and the Korea Association Resource (KARE) study Results: During median follow-ups of 4.09, 8.67, and 15.67 years in the HEXA, CAVAS, and KARE studies, respectively, there were a total of 7,331, 786, and 1,732 incident dyslipidemia events. …”
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Predicting high sensitivity C-reactive protein levels and their associations in a large population using decision tree and linear regression by Somayeh Ghiasi Hafezi, Toktam Sahranavard, Alireza Kooshki, Marzieh Hosseini, Amin Mansoori, Elham Amir Fakhrian, Helia Rezaeifard, Mark Ghamsary, Habibollah Esmaily, Majid Ghayour-Mobarhan

“…The results of the LR models showed that variables such as anxiety score, depression score, Systolic Blood Pressure, Cardiovascular disease, and HTN were significant in predicting hs-CRP levels. …”
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Analysis of the relationship between abdominal aortic calcification and frailty in the middle-aged and older US population by Rena Rehemuding, Kaisaierjiang Kadier, Xinliang Peng, Pengfei Liu, Diliyaer Dilixiati, Aikeliyaer Ainiwaer, Xiaozhu Liu, Xiangtao Liu, Xiang Ma

“…Background and Objective: Abdominal aortic calcification (AAC) is a marker of cardiovascular disease and is associated with increased mortality in middle-aged and older populations. …”
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Assessment of Risk Factors of Chronic Kidney Disease among Patients Attending Medical City Complex by Nabaa Wisam Sabri, Buthaina Ateyah Rashid, Raheem Saber Shwiehk, Azad H. Mahdy

“…There was a significant link between medical history and the outcome of this investigation (p. value < 0.05 and OR > 1) All of the risk factors for CKD were hypertension, acute kidney disease, HCV infection, hyperlipidemia, renal stones, anemia, and cardiovascular disease. alcohol consumption had a significant difference with CKD (p. value =0.004). …”
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Optimal Revascularization Strategy on Medina 0,1,0 Left Main Bifurcation Lesions in Type 2 Diabetes by Xuwei Zheng, Hongyu Peng, Donghui Zhao, Qin Ma, Kun Fu, Guo Chen, Qian Fan, Jinghua Liu

“…Diabetes mellitus (DM) is a major risk factor for cardiovascular disease. The implications of a diagnosis of DM are as severe as the diagnosis of coronary artery disease. …”
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Diagnostic prediction model for screening of elevated low-density and non-high-density lipoproteins in young Thai adults between 20 and 40 years of age by Phichayut Phinyo, Wuttipat Kiratipaisarl, Vithawat Surawattanasakul, Wachiranun Sirikul

“…Background Low-density lipoprotein cholesterol (LDL-C) and non-high-density lipoprotein cholesterol (non-HDL-C) levels are paramount in atherosclerotic cardiovascular disease risk management. However, 94.4% of Thai young adult are unaware of their condition. …”
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Pioglitazone Attenuates Drug-Eluting Stent-Induced Proinflammatory State in Patients by Blocking Ubiquitination of PPAR by Zhongxia Wang, Tao Zhang, Lizhe Sun, Ruifeng Li, Yuanyuan Wei, Xiaojuan Fan, Zuyi Yuan, Junhui Liu, Tao Chen

“…The biologic roles of peroxisome proliferator-activated receptor-γ (PPAR-γ) activators thiazolidinedione (TZD) remain controversial in cardiovascular disease. Herein, we investigated the antiinflammatory effects of pioglitazone (PIO) on circulating peripheral blood mononuclear cells (MNCs) in patients after coronary DES implantation. …”
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