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The synergistic effect of the triglyceride-glucose index and a body shape index on cardiovascular mortality: the construction of a novel cardiovascular risk marker
Published 2025-02-01“…Abstract Background Insulin resistance, represented by increased triglyceride-glucose (TyG) index levels, shows interplay with visceral obesity and together promotes cardiovascular diseases and mortality. However, significant controversies exist regarding whether modified TyG indices, such as TyG-BMI, TyG-WC, and TyG-WHtR, outperform the TyG index in predicting cardiovascular outcomes. …”
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مروری بر درمان ترکیبی با دوز ثابت برای پیشگیری ثانویه از حوادث نامطلوب قلبی- عروقی و نتایج اولیهی کارآزمایی بالینی تصادفی شدهی PersianPolypill...
Published 2024-07-01“…مقاله مروریمقدمه: این مقاله به روزرسانی مرور قبلی ما بر مطالعات بالینی درمورد نقش polypill (درمان ترکیبی با دوز ثابت) در پیشگیری ثانویه از بیماریهای قلبی- عروقی (Cardiovascular diseases) CVD و همچنین ارائهی نتایج اولیهی مطالعهی PersianPolypill میباشد.روشها: PersianPolypill یک کارآزمایی بالینی با دو بازوی موازی بر روی بیماران بستری در بیمارستان به دلیل انفارکتوس حاد میوکارد (Acute myocardial infarction) AMI میباشد. …”
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Endogenous sex hormone levels are associated with the revised Framingham Stroke Risk Profile in postmenopausal women: a longitudinal study in a Swedish cohort
Published 2025-01-01“…Abstract Background Endogenous sex hormones in postmenopausal women have been associated with risk of cardiovascular diseases. The aim of this study was to determine the association between endogenous sex hormones and the revised Framingham Stroke Risk Profile (rFSRP) in postmenopausal women. …”
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Nobiletin Attenuates Pathological Cardiac Remodeling after Myocardial Infarction via Activating PPARγ and PGC1α
Published 2021-01-01“…Nobiletin (NOB), an active monomer extracted from the peel of citrus fruit, has been reported to have beneficial effects in cardiovascular diseases. Our study was aimed at describing the specific mechanisms through which NOB protects against pathological cardiac remodeling after MI. …”
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Searching for new genes associated with the familial hypercholesterolemia phenotype using whole-genome sequencing and machine learning
Published 2023-09-01“…This disease leads to the early development of cardiovascular diseases of atherosclerotic etiology. Familial hypercholesterolemia is a monogenic disease that is predominantly autosomal dominant. …”
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Targeting the NLRP3 inflammasome abrogates cardiotoxicity of immune checkpoint blockers
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Optic nerve sheath diameter in chronic myeloproliferative disorders
Published 2024-06-01“…Several patients had a history of cardiovascular diseases, which may be related to long-term use of specific target therapy. …”
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It is time to tackle psychological determinants of obesity and eating disorders
Published 2019-03-01“…Obesity and overweight constitute an important source of morbidity, impaired quality of life and mortality, as they are associated with several cancers, diabetes and cardiovascular diseases [5]. The worldwide prevalence of obesity nearly doubled between 1980 and 2008. …”
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Impact of Comorbidities on Prognosis and Treatment Outcomes in Elderly Patients with Hodgkin Lymphoma
Published 2025-01-01“…., hypertension, diabetes, cardiovascular diseases), to assess their impact on overall survival (OS) and progression-free survival (PFS). …”
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A Case Study Identified a New Mutation in the TTN Gene for Inherited Hypertrophic Cardiomyopathy
Published 2025-01-01“…Jiangtao Dong,1– 4,* Meilin Liu,1– 3,* Qianwen Chen,1– 3,5 Lingfeng Zha1– 3 1Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 2Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 3Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 4Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 5Department of Pediatric Cardiology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430070, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lingfeng Zha, Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, People’s Republic of China, Tel +86-15827177185, Email zhalf@hust.edu.cnBackground: Hypertrophic cardiomyopathy (HCM) is the most common hereditary cardiomyopathy, with variable pathogenesis, clinical presentation, and prognosis. …”
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Prevalence of hypertension in Shenzhen, China: a population-based, cross-sectional study
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Aldehyde Dehydrogenase 2 rs671 Polymorphism is Associated with Susceptibility of Coronary Atherosclerosis in Patients with Hypertension
Published 2025-02-01“…Haisong Hou,1 Sina Huang,2 Wenyi Huang,3 Lingmei Huang,1 Zhouhua Zhang,4 Liu Liang5 1Department of Blood Transfusion, Meizhou People’s Hospital, Meizhou, People’s Republic of China; 2Department of Cardiovascular Surgery, Meizhou People’s Hospital, Meizhou, People’s Republic of China; 3Center for Surgical Operation, Meizhou People’s Hospital, Meizhou, People’s Republic of China; 4Center for Cardiovascular Diseases, Meizhou People’s Hospital, Meizhou, People’s Republic of China; 5Department of Laboratory Medicine, Meizhou People’s Hospital, Meizhou, People’s Republic of ChinaCorrespondence: Haisong Hou, Department of Blood Transfusion, Meizhou People’s Hospital, Meizhou, People’s Republic of China, Email houhaisonggd6@163.comObjective: Predisposing factors for coronary atherosclerosis in hypertensive individuals are unclear. …”
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Obsessive-compulsive personality disorder increases cognitive inflexibility in people with coronary artery disease
Published 2025-02-01“…Background: Cardiovascular diseases such as coronary artery disease (CAD) have a high prevalence of psychiatric comorbidities, that may impact clinically relevant outcomes (e.g., cognitive impairment and executive dysfunction). …”
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Pre-pregnancy BMI modifies the associations between triglyceride–glucose index in early pregnancy and adverse perinatal outcomes: a 5-year cohort study of 67,936 women in China
Published 2025-01-01“…Abstract Background Triglyceride-glucose (TyG) index was suggested as a possible surrogate for insulin resistance and a predictor for cardiovascular diseases and diabetes in the non-pregnant population. …”
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Redefining outcomes of ventricular arrhythmia for SGLT2 inhibitor medication in heart failure patients: a meta-analysis of randomized controlled trials
Published 2025-02-01“…Conclusion SGLT2 inhibitors have beneficial effects on lowering risks of VAs and SCD in patients with type 2 diabetes, cardiovascular diseases, heart failure with reduced ejection fraction (HFrEF), heart failure with preserved ejection fraction (HFpEF), and heart failure with mildly reduced ejection fraction (HFmrEF), with longer follow-up duration reinforcing these findings. …”
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Association Between Liver Fibrosis and Risk of Incident Stroke and Mortality: A Large Prospective Cohort Study
Published 2025-02-01“…Background There is a well‐established relationship between liver conditions and cardiovascular diseases. However, uncertainty persists regarding the contribution of liver fibrosis to major stroke types including ischemic stroke, intracerebral hemorrhage, and subarachnoid hemorrhage at the population level. …”
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