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The PD-1 with PD-L1 Axis Is Pertinent with the Immune Modulation of Atrial Fibrillation by Regulating T Cell Excitation and Promoting the Secretion of Inflammatory Factors
Published 2022-01-01“…Forty-five patients with atrial fibrillation admitted to the cardiology department of our hospital from July 2019 to March 2021 were selected to be included in the atrial fibrillation group, and another 45 healthy volunteers were selected as the control group to compare the changes of T cell CD69 and human leukocyte antigen-DR (HLA-DR) expression in the peripheral blood of the two study groups; compare the changes of programmed death factor-1 on CD4+ and CD8+ lymphocytes in the peripheral blood of the two groups (PD-1) expression changes and PD-L1 and PD-L2 expression changes on peripheral blood myeloid dendritic cells (mDCs) cells; compare the changes of interleukin-2, interleukin-6, interleukin-10, and interleukin-17A (IL-2, IL-6, IL-10, and IL-17), tumor necrosis factor (TNF), and interferon gamma (IFN-γ) concentrations on peripheral blood inflammatory factors in the two groups; and isolate the two groups of peripheral blood mDCs cells; α interferon upregulated PD-L1 expression in the cells and analyzed the effect of PD-L1 expression on the ability of mDCs to stimulate T cells to secrete cytokines.Results. …”
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Myocardial functional recovery following durable ventricular assist device in children
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A Case of Successful Treatment of Left Ventricular Rupture after Transcatheter Aortic Valve Implantation
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Kounis Syndrome together with Myocardial Bridging Leading to Acute Myocardial Infarction at Young Age
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Progress on long non-coding RNAs in calcific aortic valve disease
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Ferroptosis: mechanism and role in diabetes-related cardiovascular diseases
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Invasive Heart Rate Control as a Salvage Therapy in Amiodarone-induced Thyroid Storm
Published 2022-03-01Get full text
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