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    Lessons Learned and Questions Raised by an Atypical Case of Clozapine-Induced Myocarditis by Charles H. Earnshaw, Lucy Powell, Owen Haeney

    Published 2016-01-01
    “…He will be followed up with the cardiology team to ensure that his heart function returns to normal. …”
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    Survey and perspective on verification, validation, and uncertainty quantification of digital twins for precision medicine by Kaan Sel, Andrea Hawkins-Daarud, Anirban Chaudhuri, Deen Osman, Ahmad Bahai, David Paydarfar, Karen Willcox, Caroline Chung, Roozbeh Jafari

    Published 2025-01-01
    “…We examine the critical role of Verification, Validation, and Uncertainty Quantification (VVUQ) for digital twins in ensuring safety and efficacy, with examples in cardiology and oncology. We highlight challenges and opportunities for developing personalized trial methodologies, validation metrics, and standardizing VVUQ processes. …”
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