Determination of Curdlan Oligosaccharides with High-Performance Anion Exchange Chromatography with Pulsed Amperometric Detection by Lidong Cao, Huifang Tian, Miaomiao Wu, Hongjun Zhang, Puguo Zhou, Qiliang Huang

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Downregulation of FXYD2 Is Associated with Poor Prognosis and Increased Regulatory T Cell Infiltration in Clear Cell Renal Cell Carcinoma by Zedan Zhang, Yanlin Tang, Lei Li, Wuping Yang, Yawei Xu, Jingcheng Zhou, Kaifang Ma, Kenan Zhang, Hongkai Zhuang, Yanqing Gong, Kan Gong

“…FXYD2, a gene coding for the γ subunit of Na+/K+-ATPase, was demonstrated to involve in carcinogenesis recently. However, the specific role of FXYD2 in clear cell renal cell carcinoma (ccRCC) remains unknown. …”
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Relationship of smokeless tobacco uses in the perspective of oral cancer: A global burden by Ashek Elahi Noor, Boyapati Ramanarayana

“…Chronic exposure to smokeless tobacco also induces a state of chronic inflammation and immunosuppression within the oral microenvironment, fostering a permissive milieu for carcinogenesis. The mechanical trauma caused by chewing or holding smokeless tobacco products can lead to the formation of pre-cancerous lesions, providing a fertile ground for malignant transformation over time. …”
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Association of ERCC2/XPD polymorphisms and the risk of head and neck carcinoma: a systematic review, meta-analysis, trial sequential analysis, network analysis, and functional effe... by Mohammad Moslem Imani, Ali Ashabi, Farzad Rezaei, Atefe Saffar Shahroudi, Sadegh Kashkouli, Edris Sadeghi, Masoud Sadeghi

“…Abstract Objectives and aims The combination of genetic and environmental factors may contribute to the carcinogenesis of HNC. Despite the reported associations between xeroderma pigmentosum group D (XPD) polymorphisms and HNC, the results have been inconsistent, with different studies reporting varying results. …”
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Role of Bone Marrow-Derived Stem Cells in Polyps Development in Mice with ApcMin/+ Mutation by Michele Barone, Maria Principia Scavo, Raffaele Licinio, Michele Piombino, Nicola De Tullio, Rosanna Mallamaci, Alfredo Di Leo

“…We explored the hypothesis that an altered microenvironment (intestinal adenomatous polyp) could modify the differentiation program of bone marrow-derived stem cells (BMSCs), involving them in colon carcinogenesis. Sublethally irradiated 8-week-old female ApcMin/+ mice were transplanted with bone marrow (BM) cells obtained from either male age-matched ApcMin/+ (Apc-Tx-Apc) or wild type (WT) (WT-Tx-Apc) mice. …”
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Multi-omics analysis reveals the sensitivity of immunotherapy for unresectable non-small cell lung cancer by Rui Wu, Kunchen Wei, Xingshuai Huang, Yinge Zhou, Xiao Feng, Xin Dong, Hao Tang

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DNA methylation of ACADS promotes immunogenic cell death in hepatocellular carcinoma by Ze Qian, Yifan Jiang, Yacong Wang, Yu Li, Lin Zhang, Xiaofeng Xu, Diyu Chen

“…Abstract Background Altered metabolism has become an important characteristic of cancer, and acyl-CoA dehydrogenase short-chain (ACADS), a regulator of lipid synthesis, is involved in carcinogenesis-associated metabolic pathways. DNA methylation is an important mechanism for silencing ACADS in various malignancies. …”
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A Micro-RNA Connection in BRafV600E-Mediated Premature Senescence of Human Melanocytes by Gang Ren, Jingwei Feng, Ila Datar, Aaron H. Yeung, Srinivas Vinod Saladi, Yongqing Feng, Ivana de la Serna, Kam C. Yeung

“…However, the mechanism by which the oncogenic BRaf induces the senescent barrier remains poorly defined. microRNAs have regulatory functions toward the expression of genes that are important in carcinogenesis. Here we show that expression of several microRNAs is altered when the oncogenic version of BRaf is introduced in cultured primary melanocytes and these cells undergo premature cellular senescence. …”
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Mutational Analysis of a Familial Adenomatous Polyposis Pedigree with Bile Duct Polyp Phenotype by Li-jun Xie, Dan-dan Ruan, Jian-hui Zhang, Yi Li, Li Chen, Mao-lin Yan, Ming-dian Yu, Jie-wei Luo, Hui-zhen Zhang

“…Different mutation sites in APC are associated with the severity of FAP, risks of carcinogenesis, and extraintestinal manifestations. We used next-generation sequencing (NGS) and capture techniques to screen suspected mutation points in the proband in this pedigree. …”
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Dual Effect of Serum Amyloid A on the Invasiveness of Glioma Cells by Franciele Hinterholz Knebel, Renata Chaves Albuquerque, Renato Ramos Massaro, Silvya Stuchi Maria-Engler, Ana Campa

“…Evidence sustains a role for the acute-phase protein serum amyloid A (SAA) in carcinogenesis and metastasis, and the protein has been suggested as a marker for tumor progression. …”
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Transcriptome Analysis of the Effect of Acute Ammonia Stress on <i>Pseudobagrus ussuriensis</i> Liver Tissue by Shun Shi, Xiaohui Sun, Chunnuan Zhang, Chenran Lv, Yajuan Liu, Juan Du, Qian Qi

“…These results suggest that ammonia stress induces liver damage in <i>P. ussuriensis</i>, causing genetic mutations and cellular carcinogenesis, thereby accelerating cell apoptosis.…”
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GPX8 as a Novel Prognostic Factor and Potential Therapeutic Target in Primary Glioma by Zhao-shou Yang, Qin Yang, Xiao-xiao Sun, Kui Xiong, Xiao-ting Zhu, Yi-chen Wang, Qian-yao Ren, Guo-hui Wu, Shi-min Wang, Xu-qin Cao, Xiao-rong Yang, Wen-gong Jiang

“…Although glutathione peroxidase 8 (GPX8) is intimately associated with carcinogenesis, its function in primary gliomas has not yet been thoroughly understood. …”
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Clinicopathological Features and Increased Expression of Toll-Like Receptor 4 of Gastric Cardia Cancer in a High-Risk Chinese Population by Guangcan Chen, Muming Xu, Jingyao Chen, Liangli Hong, Wenting Lin, Shukun Zhao, Guohong Zhang, Guo Dan, Shuhui Liu

“…However, the clinicopathological characteristics and the carcinogenesis of GCC are unclear. Toll-like receptor 4 (TLR4) is an important innate immunity receptor and has a role in non-GCC (NGCC). …”
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Comparative evaluation of localized genotoxicity between the field of focus and scatter following exposure to cone beam computed tomography using buccal mucosal micronuclei assay:... by Rajeswari Sreeenivas, Algi Nadil, Priya Thomas, Giju George Baby, Deepu George Mathew, Pooja Latti, Jiss George

“…Considering the established link between cytotoxicity and carcinogenesis, it is imperative to use CBCT with careful deliberation, ensuring adherence to the ALARA (As Low As Reasonably Achievable) principle to effectively mitigate potential risks.…”
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Investigation of IL-17A Serum Levels in Patients with Nonmelanoma Skin Cancer by Mehdi Ghahartars, Fatemeh Sedaghat, Elham Khajavi, Amir Ali Nejat, Mahyar Malekzadeh, Abbas Ghaderi, Mohammad Javad Fattahi

“…Role of interleukin 17A (IL-17A) in carcinogenesis and cancer growth is controversial. Although some researches support its antitumor activity, some others suggest that it promotes the growth and development of different types of cancer including skin cancer by activation of STAT3. …”
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The DNMT1/miR-34a Axis Is Involved in the Stemness of Human Osteosarcoma Cells and Derived Stem-Like Cells by Xiao Liang, Chang Xu, Wanchun Wang, Xiang Li

“…The DNA methyltransferase 1 (DNMT1)/miR-34a axis promoted carcinogenesis of various types of cancers. However, no literature reported its contribution to the stemness of osteosarcoma cancer stem-like cells (OSLCs). …”
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Squamous cell carcinoma in a kidney transplant recipient after 26 years by Carolina da Silva Nunes, Andreia Bufalino, Cláudia Maria Navarro, Jorge Esquiche León, Héric de Souza Camargo, Elaine Maria Sgavioli Massucato

“…In addition, some drugs, regardless of their immunosuppressive mechanisms, have the ability to induce carcinogenesis, with cyclosporine and azathioprine being clear examples. …”
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Calpain 2 regulates IL-1α secretion and inhibits tumor development via modulating calpain 1 expression in the tumor microenvironment by Zuhairah Binte Hanafi, Yu Mei, Huey Yee Teo, Ying Zhu, Chew Chin Yong Lionel, Jing Wen Chiu, Jinhua Lu, Haiyan Liu

“…Interleukin (IL)-1α, a member of the IL-1 cytokine family, plays a crucial role in both inflammation and carcinogenesis. How IL-1α is secreted in the tumor microenvironment has been poorly understood, and we previously showed that calpain 1 cleaves pro-IL-1α for mature IL-1α secretion, which exacerbates hepatocellular carcinoma by recruiting myeloid-derived suppressor cells. …”
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High-Fat Mouse Model to Explore the Relationship between Abnormal Lipid Metabolism and Enolase in Pancreatic Cancer by Lin Qin, Kai Sun, Li Shi, Yushan Xu, Rongping Zhang

“…More and more attention has been paid to abnormal lipid metabolism as a momentous carcinogenesis mechanism. Here, we explored the relationship between abnormal lipid metabolism, enolase, and pancreatic cancer by clinical data analysis. …”
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The impaired response of nasal epithelial cells to microplastic stimulation in asthma and COPD by Magdalena Paplińska-Goryca, Paulina Misiukiewicz-Stępień, Monika Wróbel, Katarzyna Mycroft-Rzeszotarska, Dorota Adamska, Julia Rachowka, Milena Królikowska, Krzysztof Goryca, Rafał Krenke

“…Microplastic stimulation altered the response of airway epithelial cells in obstructive lung diseases differently than in controls, linking to Th2 inflammation, stress response modulation, and carcinogenesis. Asthmatic and COPD epithelial cells are more susceptible to damage from microplastic fibre exposure.…”
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