Methylation Status of Vitamin D Receptor Gene Promoter in Benign and Malignant Adrenal Tumors by Catia Pilon, Andrea Rebellato, Riccardo Urbanet, Vincenza Guzzardo, Rocco Cappellesso, Hironobu Sasano, Ambrogio Fassina, Francesco Fallo

“…The association between VDR gene promoter methylation and reduced VDR gene expression is not a rare event in ACC, suggesting that VDR epigenetic inactivation may have a role in adrenocortical carcinogenesis.…”
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Helicobacter pylori y cáncer gástrico by Ludmila Martínez Leyva, Teresita de Jesús Montero González, Felipe Neri Piñol Jiménez, Amada Belquis Palomino Besada, Miguel González-Carbajal Pascual, Danay Días Morejón

“…Conclusiones: El Helicobacter pylori favorece la carcinogénesis gástrica, aunque existen otros factores de riesgo para el surgimiento del cáncer gástrico como son: la historia familiar, la pobre ingestión de frutas y vegetales y el bajo nivel socioeconómico.…”
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Gastric Microbiota Associated with Gastric Precancerous Lesions in <i>Helicobacter pylori</i>-Negative Patients by Han-Na Kim, Min-Jeong Kim, Jonathan P. Jacobs, Hyo-Joon Yang

“…These alterations might contribute to chronic gastric mucosal inflammation, promoting carcinogenesis in the absence of <i>H. pylori</i> infection.…”
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Dietary pattern and risk of thyroid cancer: a systematic review and meta-analysis protocol by Kleyton Santos Medeiros, Jose Brandao-Neto, Yasmin Guerreiro Nagashima, Aline Alves Soares, Camila Xavier Alves, Marcia Marilia Gomes Dantas Lopes

“…There are interesting connections among diet, environment, metabolism and thyroid carcinogenesis; a deeper comprehension of the underlying mechanisms should help the identification of modifiable risk factors for thyroid cancer. …”
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Extended UVB Exposures Alter Tumorigenesis and Treatment Efficacy in a Murine Model of Cutaneous Squamous Cell Carcinoma by Erin M. Burns, Kathleen L. Tober, Judith A. Riggenbach, Donna F. Kusewitt, Gregory S. Young, Tatiana M. Oberyszyn

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Expressions of CXCL12/CXCR4 in Oral Premalignant and Malignant Lesions by Juan Xia, Na Chen, Yun Hong, Xiaobing Chen, Xiaoan Tao, Bin Cheng, Yulei Huang

“…Our results indicated that CXCL12/CXCR4 axis may play roles from early steps of oral malignant transformation and contribute to the progress of oral carcinogenesis.…”
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Systemic Inflammatory Cytokines Predict the Infectious Complications but Not Prolonged Postoperative Ileus after Colorectal Surgery by G. S. A. Boersema, Z. Wu, A. G. Menon, G. J. Kleinrensink, J. Jeekel, J. F. Lange

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Use of Glucagon-Like Peptide-1 Receptor Agonists Does Not Increase the Risk of Cancer in Patients with Type 2 Diabetes Mellitus by Mijin Kim, Seung Chan Kim, Jinmi Kim, Bo Hyun Kim

“…However, there are concerns about carcinogenesis in the pancreas and thyroid gland. We aimed to evaluate the site-specific incidence of cancer in patients with T2DM-treated GLP-1 RAs using a nationwide cohort. …”
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Microbial signatures in head and neck squamous cell carcinoma: an in silico study by Loganathan KAVITHA, Manogaran KUZHALMOZHI, Jayaseelan VIJAYASHREE PRIYADHARSINI, Arunachalam ARUN KUMAR, Krishna Mohan Rao UMADEVI, Kannan RANGANATHAN

“…Conclusion The oral-gut microbial dysbiosis, as reflected by the differential abundance of bacterial species in oral and GI carcinomas, suggests the implication of tumor microbiome and their genomic interactions with the host in carcinogenesis.…”
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Group 2 Innate Lymphoid Cells Are Involved in Skewed Type 2 Immunity of Gastric Diseases Induced by Helicobacter pylori Infection by Rong Li, Xiao-xia Jiang, Lin-fang Zhang, Xiao-ming Liu, Ting-zi Hu, Xiu-juan Xia, Ming Li, Can-xia Xu

“…H. pylori induces a complicated local and systematic immune response and contributes to the carcinogenesis of gastric cancer. A primary type 1 immune response is evoked by H. pylori since its occurrence. …”
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Morphopathology of the Prussian carp (Carassius auratus gibelio Bloch, 1782) liver under the effect of allyl acetate by M. Koziy

“…Under conditions of prolonged exposure to chemical stress, carcinogenesis was activated in the fish liver. This was evidenced by a characteristic picture of a failure of the moment of transition of the sequence and periodicity of morphogenetic processes, which manifested itself in the form of atypical cellular polymorphism. …”
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Consideraciones teóricas sobre la perspectiva ecológica-evolutiva del cáncer by Armando Ernesto Pérez Cala, Edgar Benítez Sánchez, Yelina de la Caridad Dominica Esteris

“…Las conclusiones derivadas de estos principios ecológicos y evolutivos, deben servir para una mejor caracterización de los factores dependientes tanto de los factores biológicos como de los ambientales que influyen en el riesgo de la carcinogénesis. Más del 90 % del incremento del riesgo basal de cáncer, incluso en especies naturales, obedecen a la actividad humana, y por tanto, pueden ser modificables.  …”
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Natural products based on Correa's cascade for the treatment of gastric cancer trilogy: Current status and future perspective by Wenhao Liao, Jing Wang, Yuchen Li

“…This review is the first to investigate and summarize the multi-step effects and regulatory mechanisms of NPs on the Correa's cascade in gastric carcinogenesis. In phase I, NPs modulate Helicobacter pylori urease activity, motility, adhesion, virulence factors, and drug resistance, thereby inhibiting H. pylori-induced gastric mucosal inflammation and oxidative stress, and facilitating ulcer healing. …”
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Hypermethylation at 45S rDNA promoter in cancers. by Trang Thi Quynh Tran, Trang Hien Do, Tung The Pham, Phương Thi Thu Luu, Oanh Minh Pham, Uyen Quynh Nguyen, Linh Dieu Vuong, Quang Ngoc Nguyen, Tuan Van Mai, Son Van Ho, Than Thi Nguyen, Lan Thi Thuong Vo

“…Hence, clarifying hypo- or hypermethylation of rDNA will unravel its additional cellular functions, including organization of genome architecture and regulation of gene expression, in response to growth signaling, cellular stressors, and carcinogenesis. Using the bisulfite-based quantitative real-time methylation-specific PCR (qMSP) method after ensuring unbiased amplification and complete bisulfite conversion of the minuscule DNA amount of 1 ng, we established that the rDNA promoter was significantly hypermethylated in 107 breast, 65 lung, and 135 colon tumour tissue samples (46.81%, 51.02% and 96.60%, respectively) as compared with their corresponding adjacent normal samples (26.84%, 38.26% and 77.52%, respectively; p < 0.0001). …”
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Temporally and Spatially Controlled Age-Related Prostate Cancer Model in Mice by Sen Liu, Keyi Shen, Zixuan Li, Seleste Rivero, Qiuyang Zhang

“…This novel approach provides a powerful age-related murine model for PCa, emphasizing the effect of aging on prostate carcinogenesis.…”
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Malignant melanoma of the ear - a literature review of a rare otological tumor by Nicol Dardzińska, Marta Dziedziak, Aleksandra Grzegorczyk, Natalia Hopej, Justyna Korus

“…In each of these parts the process of carcinogenesis can occur. The tumor develops from mutated melanocytes. …”
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Expression of a Secretory Protein C1qTNF6, a C1qTNF Family Member, in Hepatocellular Carcinoma by Tamotsu Takeuchi, Yoshihiro Adachi, Tomoko Nagayama

“…However, the pathobiological property of C1qTNF6 in carcinogenesis remains unclear. Here, we investigated the expression status of C1qTNF6 in human hepatocellular carcinomas and subsequently attempted to determine the role of C1qTNF6 in tumor neovascularization. …”
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An untargeted metabolomic analysis of acute AFB1 treatment in liver, breast, and lung cells. by Heidi H Cao, Sabrina Molina, Susan Sumner, Blake R Rushing

“…A better understanding of how AFB1 disrupts metabolism would provide insight into how this mycotoxin leads to carcinogenesis, growth impairment, and/or immunomodulation, and may reveal potential targets for pharmacological or nutritional interventions to protect against these effects. …”
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The role of HSPA14 in breast cancer: implications for tumorigenesis, immune response modulation, and personalized therapies by Ruipeng Zhao, Xiaocun Zhu, Wan Wei, Linlin Zhen

“…Background Heat shock proteins have been implicated in the process of carcinogenesis. HSPA14, a member of the heat shock protein family, remains poorly understood in terms of its significance and pathomechanisms in breast cancer.Methods We analyzed the expression levels of HSPA14 and its prognostic significance in breast cancer using TCGA data. …”
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Neoadjuvant apatinib addition to sintilimab and carboplatin-taxane based chemotherapy in patients with early triple-negative breast cancer: the phase 2 NeoSAC trial by Guoshuang Shen, Zhilin Liu, Miaozhou Wang, Yi Zhao, Xinlan Liu, Yujin Hou, Wenbiao Ma, Jingqi Han, Xiaofeng Zhou, Dengfeng Ren, Fuxing Zhao, Zitao Li, Shifen Huang, Yongzhi Chen, Yingjian He, Yan Liu, Zijun Zhu, Yongxin Li, Jinming Li, Mengting Da, Hongnan Mo, Feng Du, Liang Cui, Jing Bai, Zhen Liu, Fei Ma, Jiuda Zhao

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