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461
Tilia species (linden) exert anti-cancer effects on MIA PaCa-2 cells through the modulation of oxidative stress and inflammation
Published 2025-01-01“…Overall, our results highlight a potential use for Tilia extracts, particularly T. rubra, in pancreatic cancer treatment by modulating cell death.…”
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462
Immunotherapy in Recurrent Ovarian Cancer
Published 2025-01-01“…Conclusions: Immunotherapy significantly advances recurrent ovarian cancer treatment, with various combinations potentially improving outcomes. …”
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463
Exploring preconception health in adolescents and young adults: Identifying risk factors and interventions to prevent adverse maternal, perinatal, and child health outcomes-A scopi...
Published 2024-01-01“…It also suggested an increase in the odds of congenital anomalies among children born to mothers aged 20-24 years. Furthermore, cancer treatment during childhood or young adulthood was associated with an increased risk of preterm birth, LBW, and stillbirths. …”
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464
Risk Factors of Lymph Edema in Breast Cancer Patients
Published 2013-01-01“…Lymphedema secondary to breast cancer treatment is a common and serious problem for disease survivors. …”
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465
Accepting your Body after Cancer (ABC), a group-based online intervention for women treated for breast cancer: study protocol for a feasibility randomised controlled trial
Published 2025-01-01“…While increasing numbers of women are living beyond breast cancer, treatment-related body image concerns are common and associated with adverse consequences. …”
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466
The role of interleukin-17 in inflammation-related cancers
Published 2025-01-01“…This comprehensive analysis aims to enhance our understanding of IL-17 and its potential role in cancer treatment.…”
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467
Interaction of norsecurinine-type monomeric and dimeric alkaloids with α-tubulin: a molecular docking study
Published 2024-05-01“…Aim: New microtubule-targeting agents are needed to improve cancer treatment. The recent characterization of the anticancer alkaloid securinine as a tubulin-binding agent prompted us to explore the interaction of related monomeric and dimeric analogues with tubulin. …”
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468
Revolutionizing radiotherapy: gold nanoparticles with polyphenol coating as novel enhancers in breast cancer cells—an in vitro study
Published 2025-01-01“…The results showed that green-synthesized AuNPs significantly enhanced the therapeutic effects of radiotherapy at lower radiation doses, indicating their potential as a valuable addition to breast cancer treatment.…”
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469
Mindfulness-Based Stress Reduction in Breast Cancer Survivors with Chronic Neuropathic Pain: A Randomized Controlled Trial
Published 2022-01-01“…Many breast cancer survivors live with chronic neuropathic pain (CNP) after breast cancer treatment. Despite pharmacological management of CNP, many women continue to report disabling pain and reduced quality of life. …”
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470
PMAIP1-mediated glucose metabolism and its impact on the tumor microenvironment in breast cancer: Integration of multi-omics analysis and experimental validation
Published 2025-02-01“…Thus, this study aimed to develop a glucose metabolism–tumor microenvironment score to provide new perspectives on breast cancer treatment. Method: Data were acquired from the Gene Expression Omnibus and UCSC Xena databases, and glucose-metabolism-related genes were acquired from the Gene Set Enrichment Analysis database. …”
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471
SNP rs9364554 Modulates Androgen Receptor Binding and Drug Response in Prostate Cancer
Published 2025-01-01“…(1) Background: Prostate cancer treatment efficacy is significantly influenced by androgen receptor (AR) signaling pathways. …”
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472
Exploring Glypican-3 targeted CAR-NK treatment and potential therapy resistance in hepatocellular carcinoma.
Published 2025-01-01“…Chimeric antigen receptor (CAR)-modified natural killer (NK) cells have demonstrated potent anti-tumor effects, making them as a promising immunotherapy strategy for cancer treatment. Glypican-3 (GPC3), a cell surface oncofetal glycoprotein, is highly expressed in most HCC tissues, but not in normal tissues, and functions as a key driver of carcinogenesis. …”
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473
Synthesis and Characterization of Green Zinc Oxide Nanoparticles with Antiproliferative Effects through Apoptosis Induction and MicroRNA Modulation in Breast Cancer Cells
Published 2020-01-01“…Changes in the expression of microRNAs can affect cancer cells’ viability and behavior and the impact on cancer treatment. In this study, the expression of miR-155-5p, miR-203a-3p, and miR-223-3p in the MCF7 cancer cell line was studied when exposed to ZnO nanoparticles synthesized through a green route. …”
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474
<i>shp-2</i> gene knockout upregulates CAR-driven cytotoxicity of YT NK cells
Published 2020-03-01“…Adoptive transfer of NK cells is a promising approach to fight cancer; however, for their successful use in cancer treatment, it is necessary to ensure their robust accumulation at tumor foci, provide resistance to the immunosuppressive tumor microenvironment, and to engineer them with higher cytotoxic activity. …”
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475
Targeting Inhibition of Accumulation and Function of Myeloid-Derived Suppressor Cells by Artemisinin via PI3K/AKT, mTOR, and MAPK Pathways Enhances Anti-PD-L1 Immunotherapy in Mela...
Published 2022-01-01“…Artemisinin (ART), the most effective antimalarial drug with tumoricidal and immunoregulatory activities, is a potential option for cancer treatment. Although ART is reported to reduce MDSC levels in 4T1 breast tumor model and improve the therapeutic efficacy of anti-PD-L1 antibody in T cell lymphoma-bearing mice, how ART influences MDSC accumulation, function, and molecular pathways as well as MDSC-mediated anti-PD-L1 resistance in melanoma or liver tumors remains unknown. …”
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476
Factors Influencing Treatment-Seeking Behavior Among Caregivers of Children with Cancer: A Scoping Review
Published 2025-02-01“…Expanding the cancer service network in developing countries could improve public access to pediatric cancer services.Keywords: children, factors, cancer, treatment delayed, health-seeking behavior…”
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477
PD-L1 monoclonal antibody alleviated MI injury of left ventricular function via modulating CD47/SHP2/SIRPα/SYK/FcγR signalings in tumor associated macrophages
Published 2025-01-01“…In vitro Western blotting analysis revealed that PD-L1 mAb can modulate the CD47/SHP2/SIRPα/SYK/FcγR signaling pathway, thereby affecting breast cancer. Treatment with a STING inhibitor significantly reduced the cGAMP effect, leading to improved left ventricular function in mice with MI. …”
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478
Novel thiazolyl-pyrimidine derivatives as potential anticancer agents: Synthesis, biological evaluation, and molecular docking studies
Published 2025-01-01“…The compounds may serve as adjuvants in cancer treatment. In silico ADMET studies revealed that the synthesized compounds exhibit favorable oral bioavailability profiles.…”
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479
Relation of Malnutrition and Nosocomical Infections in Cancer Patients in Hospital: An Observational Study
Published 2022-01-01“…The most frequent reason for admission was cancer treatment (19.6%), followed by infections (18.7%) and digestive tract symptoms (18.7%). …”
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480
Perceptions in 3.6 Million Web-Based Posts of Online Communities on the Use of Cancer Immunotherapy: Data Mining Using BERTopic
Published 2025-02-01“… BackgroundImmunotherapy has become a game changer in cancer treatment. The internet has been used by patients as a platform to share personal experiences and seek medical guidance. …”
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