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421
Routine Surveillance of Upper Urinary Tract Imaging for Diagnosing Upper Urinary Tract Urothelial Cancer Recurrence in Patients with Nonmuscle Invasive Bladder Cancer
Published 2024-01-01“…A single-institute long-term follow-up cohort study to evaluate the clinical impact of routine surveillance imaging and identify risk factors for upper urinary tract urothelial cancer recurrence after nonmuscle invasive bladder cancer treatment was conducted. Methods and Materials. …”
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422
Combination therapy of low-dose radiotherapy and immunotherapy in advanced metastatic nasopharyngeal carcinoma: a case report and literature review
Published 2025-01-01“…Low-dose radiotherapy (LDRT) is increasingly being investigated for potential cancer treatment. When combined with immune checkpoint inhibitors, LDRT has been shown to significantly improve the immune microenvironment of tumors, thereby promote the immune attack on tumor cells. …”
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423
Detection of mutations in plasma cell-free DNA of colorectal cancer patients and comparison with cancer panel data for tissue samples of the same cancers
Published 2019-11-01“…Liquid biopsy has been suggested as an attractive tool for the non-invasive follow-up of cancer treatment outcomes. In this study, we aimed to verify whether the mutations identified in primary tumor tissue samples could be consistently detected in plasma cell–free DNA (cfDNA) by digital polymerase chain reaction (dPCR). …”
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424
Leveraging mRNA technology for antigen based immuno-oncology therapies
Published 2025-01-01“…The application of messenger RNA (mRNA) technology in antigen-based immuno-oncology therapies represents a significant advancement in cancer treatment. Cancer vaccines are an effective combinatorial partner to sensitize the host immune system to the tumor and boost the efficacy of immune therapies. …”
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425
Endoscopic Submucosal Dissection for Gastric Tube Carcinoma after Esophagectomy Contributes to Long-Term Outcomes
Published 2022-01-01“…The curability of GTC with ESD was evaluated histologically according to the Japanese Gastric Cancer Treatment Guidelines. Patient characteristics and procedural and long-term outcomes were analyzed. …”
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426
Advancements in Managing Anthracycline-Induced Cardiotoxicity: Insights from Interventional Clinical Trials
Published 2025-01-01“…Mei Zhao,1 Xiaohong Zhang,1 Dongyang Zhou,2 Junxian Song3– 5 1Department of Pharmacy, Peking University People’s Hospital, Beijing, People’s Republic of China; 2Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK; 3Department of Cardiology, Peking University People’s Hospital, Beijing, People’s Republic of China; 4Beijing Key Laboratory of Early Prediction and Intervention of Acute Myocardial Infarction, Peking University People’s Hospital, Beijing, People’s Republic of China; 5Center for Cardiovascular Translational Research, Peking University People’s Hospital, Beijing, People’s Republic of ChinaCorrespondence: Junxian Song, Department of Cardiology, Peking University People’s Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, 100044, People’s Republic of China, Email sjx221@163.comPurpose: Anthracycline-induced cardiotoxicity (AIC) is a significant complication in cancer treatment, impacting long-term health outcomes. …”
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427
Lipoic acid-boronophenylalanine-derived multifunctional vesicles for cancer chemoradiotherapy
Published 2025-02-01“…Our findings highlight the potential of LA-BPA derivatives in developing more precise, effective, and less detrimental chemoradiotherapy approaches, marking an advancement in nanomedicine for cancer treatment.…”
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428
Bioadhesive Chitosan Films Loading Curcumin for Safe and Effective Skin Cancer Topical Treatment
Published 2024-12-01“…<b>Background/Objectives</b>: This study aimed to evaluate the safety and efficacy of chitosan-based bioadhesive films for facilitating the topical delivery of curcumin in skin cancer treatment, addressing the pharmacokinetic limitations associated with oral administration. …”
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429
Machine Learning-Based Radiomics Analysis for Identifying KRAS Mutations in Non-Small-Cell Lung Cancer from CT Images: Challenges, Insights and Implications
Published 2025-01-01“…Kirsten Rat Sarcoma viral oncogene homolog (KRAS) is a frequently occurring mutation in non-small-cell lung cancer (NSCLC) and influences cancer treatment and disease progression. In this study, a machine learning (ML) pipeline was applied to radiomic features extracted from public and internal CT images to identify KRAS mutations in NSCLC patients. …”
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430
Intratumoral <i>Fusobacterium nucleatum</i> in Pancreatic Cancer: Current and Future Perspectives
Published 2024-12-01“…Additionally, compelling research suggests that <i>Fn</i> may exert detrimental effects on cancer treatment outcomes. This paper extends the perspective to pancreatic cancer associated with <i>Fn</i>. …”
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431
Enhancement of chemotherapy using oncolytic virotherapy: Mathematical and optimal control analysis
Published 2018-11-01“…Oncolytic virotherapy has been emerging as a promising novel cancer treatment which may be further combined with the existing therapeutic modalities to enhance their effects. …”
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432
Metal‐based nanomaterials and nanocomposites as promising frontier in cancer chemotherapy
Published 2023-04-01“…Several metal‐based NMs have been studied with the expectation of finding a cure for cancer treatment. In this review, the current development and the potential of plant and metal‐based NMs with their effects on size and shape have been discussed along with their more effective usage in cancer diagnosis and treatment.…”
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433
Enhancing magnetic hyperthermia: Investigating iron oxide nanoparticle coating and stability
Published 2025-01-01“…Cancer treatment research focuses on overcoming the limitations of conventional treatment methods, especially in addressing treatment-resistant malignancies. …”
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434
Ezetimibe Anticancer Activity via the p53/Mdm2 Pathway
Published 2025-01-01“…Due to poor oral bioavailability, Ezetimibe must be administered parenterally for cancer treatment.…”
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435
Enhanced Morbidity of Pectoralis Major Myocutaneous Flap Used for Salvage after Previously Failed Oncological Treatment and Unsuccessful Reconstructive Head and Neck Surgery
Published 2012-01-01“…An association was identified between the development of major complications and reconstruction of the hypopharynx (𝑃=0.013) as well as in patients submitted to surgery in association with radiation therapy as a previous cancer treatment (𝑃=0.002). The former condition is also associated with major reconstruction failure (𝑃=0.018). …”
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436
RNA modifications in cancer
Published 2025-01-01“…By addressing these aspects, this review aims to bridge current research gaps and underscore the therapeutic potential of targeting RNA modifications to improve cancer treatment strategies and patient outcomes.…”
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437
Enhanced targeted treatment of cervical cancer using nanoparticle-based doxycycline delivery system
Published 2025-01-01“…These results underscore the potential of HA-Chitosan-based DOX nanoparticles in improving cervical cancer treatment through enhanced targeted delivery and inhibition of tumor-promoting mechanisms.…”
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438
Tanshinlactone triggers methuosis in breast cancer cells via NRF2 activation
Published 2025-01-01“…Additionally, tanshinlactone demonstrated effectiveness against lapatinib-resistant breast cancer cells, suggesting its potential as a therapeutic agent for overcoming drug resistance in cancer treatment.ConclusionTanshinlactone as a novel therapeutic agent, is capable of selectively inhibiting ER+ and HER2+/EGFR + breast tumors through a unique mechanism of inducing catastrophic macropinocytosis. …”
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439
Grade IV oral mucositis treatment with Brazilian green propolis mucoadherent gel
Published 2023-10-01“…Rapid treatment of OM means restoring quality of life to patients and lowering the cost of cancer treatment for public health. There male patients with oral carcinoma undergoing radiotherapy treatment were followed between August 2018 and April 2019. …”
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440
The Contribution of Secondary Particles Following Carbon Ion Radiotherapy to Soft Errors in CIEDs
Published 2024-01-01“…<italic>Introduction:</italic> While carbon ion radiotherapy is highly effective in cancer treatment, it has a high risk of causing soft error, which leads to malfunctions in cardiac implantable electrical devices (CIEDs). …”
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