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361
Contralateral nodal failures in oropharyngeal cancers after TORS and unilateral neck management: a retrospective study
Published 2021-12-01“…Conclusion In selected patients with lateralized oropharyngeal cancer, treatment with TORS and ipsilateral management of the neck may be oncologically safe without significant risk of contralateral failure. …”
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362
Multidisciplinary Collaboration and Novel Technological Advances in Hadron Therapy
Published 2025-02-01“…Hadron Therapy (HT), which employs accelerated beams of protons, carbon ions, and other charged particles, represents a significant frontier in cancer treatment. This modality offers superior precision and efficacy compared to conventional methods, delivering therapeutic the dose directly to tumours while sparing healthy tissue. …”
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363
Fluorescence imaging‐guided lipid droplets‐localized photodynamic therapy
Published 2025-01-01“…Abstract Photodynamic therapy (PDT) has emerged as a promising strategy for cancer treatment due to its non‐invasive nature and high specificity toward malignant tissues. …”
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364
Integration of circulating tumor DNA in biliary tract cancer: the emerging landscape
Published 2024-12-01“…Precision medicine has emerged as a cornerstone in cancer treatment revolutionizing our approach across malignancies. …”
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365
Quantitative impact of immunomodulation versus oncolysis with cytokine-expressing virus therapeutics
Published 2015-03-01“…The past century's description of oncolytic virotherapy as a cancer treatment involving specially-engineered viruses that exploit immune deficiencies to selectively lyse cancer cells is no longer adequate. …”
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366
Ellagic acid: A potent glyoxalase-I inhibitor with a unique scaffold
Published 2021-03-01“…The glyoxalase system, particularly glyoxalase-I (GLO-I), has been approved as a potential target for cancer treatment. In this study, a set of structurally diverse polyphenolic natural compounds were investigated as potential GLO-I inhibitors. …”
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367
Natural killer cell engagers for cancer immunotherapy
Published 2025-01-01“…Ultimately, this article presents an overview of the current landscape and future prospects of NKCE-based cancer immunotherapy, emphasizing its potential to revolutionize cancer treatment.…”
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368
Evaluating Medicinal Plants for Anticancer Activity
Published 2014-01-01“…Most chemotherapeutic drugs for cancer treatment are molecules identified and isolated from plants or their synthetic derivatives. …”
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369
Docking to Explicate Interface between Plant-Originated Inhibitors and E6 Oncogenic Protein of Highly Threatening Human Papillomavirus 18
Published 2015-06-01“…Traditionally, different natural compounds such as withaferin A, artemisinin, ursolic acid, ferulic acid, (-)-epigallocatechin-3-gallate, berberin, resveratrol, jaceosidin, curcumin, gingerol, indol-3-carbinol, and silymarin have been used as hopeful source of cancer treatment. These natural inhibitors have been shown to block HPV infection by different researchers. …”
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370
Anticancer effects of PEP06 (TB01) in combination with Trifluridine/Tipiracil (TAS-102) in a xenograft model of human colorectal cancer
Published 2024-12-01“…Recently years, drug combination therapy has become a promising strategy for cancer treatment. Objective To evaluate the therapeutic efficacy of the combination of the anti-angiogenic drug PEP06 (TB01) and the cytotoxic drug Trifluridine/Tipiracil (TAS-102) in human CRC HCT-116 xenograft mouse model. …”
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371
Current status and future prospects of molecular imaging in targeting the tumor immune microenvironment
Published 2025-01-01“…The future outlook emphasizes the potential of molecular imaging to enhance personalized cancer treatment through the integration of artificial intelligence and the development of novel imaging probes. …”
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372
Adjuvant Radiochemotherapy with a 23-Month Overall Survival Time in a Patient after a Surgery due to Splenic Hemangiosarcoma Rupture: A Case Report with the Literature Review
Published 2018-01-01“…The case shows that adjuvant radiotherapy as part of cancer treatment strategy may prolong the overall survival.…”
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373
Clinical Impact of Sphingosine-1-Phosphate in Breast Cancer
Published 2017-01-01“…We suggest that S1P is one of the key molecules to overcome the resistance to the drug therapies, such as hormonal therapy, anti-HER2 therapy, or chemotherapy, all of which are crucial aspects of a breast cancer treatment.…”
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374
Identification of Proteins and Genes Associated with Hedgehog Signaling Pathway Involved in Neoplasm Formation Using Text-Mining Approach
Published 2024-03-01“…Analysis of molecular mechanisms that lead to the development of various types of tumors is essential for biology and medicine, because it may help to find new therapeutic opportunities for cancer treatment and cure including personalized treatment approaches. …”
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375
Canine Mammary Tumors as a Potential Model for Human Breast Cancer in Comparative Oncology
Published 2024-01-01“…In total, 64 canine mammary tumors were selected to study the most common markers, which are applicable for human breast cancer treatment, including estrogen and progesterone receptors (ER and PR), human epidermal growth factor (HER2/neu), Ki67, and cyclooxygenase 2 (Cox2). …”
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376
Enhancing the efficacy of near-infrared photoimmunotherapy through intratumoural delivery of CD44–targeting antibody–photoabsorber conjugatesResearch in context
Published 2025-02-01“…Summary: Background: Photoimmunotherapy (PIT) is a potent modality for cancer treatment. The conventional PIT regimen involves the systemic delivery of an antibody–photoabsorber conjugate, followed by a 24-h waiting period to ensure adequate localisation on the target cells. …”
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377
Lidocaine could promote the cuproptosis through up-regulating the long noncoding RNA DNMBP-AS1 in Hep-2 cells
Published 2025-01-01“…The results of this study offered initial optimism that lidocaine could be used in an adjuvant or neoadjuvant fashion in cancer treatment.…”
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378
Organ preservation, for rectal cancer: general overview of the latest data from phase III randomized trials
Published 2025-01-01“…Despite the lack of international consensus on the optimal OP protocol, past and ongoing randomized trials provide valuable findings into the evolving management strategies of rectal cancer treatment. The presented data supports the role of randomized phase III trials to provide evidence for a change in clinical practice. …”
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379
Differential Reponses of Hematopoietic Stem and Progenitor Cells to mTOR Inhibition
Published 2015-01-01“…Therefore, targeting of the mTOR pathway is an attractive strategy for cancer treatment and several mTOR inhibitors, including AZD8055 (AZD), a novel dual mTORC1/2 inhibitor, are currently in clinical trials. …”
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380
Targeting fucosyltransferase FUT8 as a prospective therapeutic approach for DLBCL
Published 2025-01-01“…The emergence of natural products and their derivatives has notably influenced cancer treatment, making morusinol, a medicine-derived monomer, a promising candidate. …”
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