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341
A Golgi apparatus‑related subtype and risk signature predicts prognosis and evaluates immunotherapy response in gastric cancer
Published 2025-01-01“…GARRS, validated for its prognostic, immune infiltration, and drug sensitivity predictive abilities, offers new insights into gastric cancer treatment strategies.…”
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342
Transposon mediated functional genomic screening for BRAF inhibitor resistance reveals convergent Hippo and MAPK pathway activation events
Published 2025-01-01“…Abstract Genotype-informed anticancer therapies such as BRAF inhibitors can show remarkable clinical efficacy in BRAF-mutant melanoma; however, drug resistance poses a major hurdle to successful cancer treatment. Many resistance events to targeted therapies have been identified, suggesting a complex path to improve therapeutics. …”
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343
Currents status of radiotracers for breast cancer imaging in PET
Published 2025-03-01“…These radiopharmaceuticals, based on radionuclides, enable both imaging and therapeutic applications, leading to personalized cancer treatment. Techniques such as PET, SPECT, and the use of nanoparticles for theranostics are at the forefront of innovation, offering improved precision in both diagnosis and therapy. …”
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344
Targeting the 8-oxodG Base Excision Repair Pathway for Cancer Therapy
Published 2025-01-01“…This review provides a robust reference for scientific researchers, offering an updated perspective on small-molecule inhibitors targeting the 8-oxodG-BER pathway and highlighting their potential role in expanding cancer treatment strategies.…”
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345
Thermal performance and MHD peristaltic flow of hybrid nanofluid (Au-Ta/Blood) in an asymmetric conduit with electro-osmosis and shape factor effects
Published 2025-02-01“…The current research aims to create a mathematical model for targeted drug delivery systems, applicable in areas like cancer treatment, genetic disorder therapies, and infection management. …”
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346
Harnessing the immunomodulatory potential of natural products in precision medicine—a comprehensive review
Published 2024-06-01“…Clinical applications of NP-based immunotherapies, such as curcumin and resveratrol in cancer treatment, highlight their diverse pharmacological properties. …”
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347
Biodegradable triboelectric nanogenerator as a implantable power source for embedded medicine devices
Published 2024-03-01“…Our work demonstrates the broad potential of BI-TENGs in the field of cancer treatment.…”
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348
Exploring therapeutic strategies for androgen-independent prostate cancer using a magnetic coculture platform
Published 2025-06-01“…Notably, our findings revealed that a dosage of 2.5 µM Fenbendazole significantly eradicated PC3 cells with minimal damage to surrounding fibroblasts, thus indicating its potential for prostate cancer treatment in-vivo models.…”
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349
Experience of Initial Symptoms of Breast Cancer and Triggers for Action in Ethiopia
Published 2012-01-01“…Methods. 69 participants in a comprehensive breast cancer treatment program at the main national cancer hospital in Ethiopia were interviewed using mixed qualitative and quantitative approaches. …”
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350
Effects of Scheduled Exercise on Cancer-Related Fatigue in Women with Early Breast Cancer
Published 2014-01-01“…While physical activity during cancer treatment is found beneficial for breast cancer patients, evidence indicates ambiguous findings concerning effects of scheduled exercise programs on treatment-related symptoms. …”
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351
Deep weighted survival neural networks to survival risk prediction
Published 2024-11-01“…Abstract Survival risk prediction models have become important tools for clinicians to improve cancer treatment decisions. In the medical field, using gene expression data to build deep survival neural network models significantly improves accurate survival prognosis. …”
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352
Design and Optimization of the Circulatory Cell-Driven Drug Delivery Platform
Published 2021-01-01“…This review specifically covers (a) the properties of red blood cells, monocytes, macrophages, neutrophils, natural killer cells, T lymphocytes, and mesenchymal stem cells; (b) the loading strategies to balance cargo amounts and cell function balance; (c) the cascade strategies to improve cell-driven targeting delivery efficiency; and (d) the features and applications of cell membranes, artificial cells, and extracellular vesicles in cancer treatment.…”
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353
Evaluation of Antitumer activity of Ammi Majus seeds extract on Some cancer cell line
Published 2025-01-01“…The cancer cell lines were treated with different concentrations (6.25 ,12.5 ,25, 50, 100,200 )of the Ammi majus seeds extracts (aqueous and ethanolic extracts).The results showed the effect of both seeds extracts (aqueous and alcoholic) on the growth of Helacell lines increased with increasing the concentration and give highest inhibition rate( 3.93 ± 72.69 % and 3.93± 91.87 ) in respectively ,at a concentration ( 200 µg/ml,)Wheareas the highest inhibition rate for the seedsextracts (aqueous and alcoholic) on the growth of HepG2 was ( 3.18 ± 68.86 % and 1.36± 79.31 %) in respectively, at a concentration ( 200µg/ml ), The current study concluded that the aqueous and alcoholic extracts of the Ammimajus seeds plant has an effect in the process of inhibiting cancer cell lines.making this plant a promising candidate for cancer treatment. …”
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354
Insights into CSF-1/CSF-1R signaling: the role of macrophage in radiotherapy
Published 2025-02-01“…Recently, the promising therapeutic potential of CSF-1/CSF-1R signaling pathway inhibition in cancer treatment is widely used. Furthermore, inhibition of CSF-1/CSF-1R signaling combined with radiotherapy has been extensively studied to reduce immunosuppression and promote abscopal effect. …”
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355
Optimizing the Future: A Game Theory to Tumor Therapeutic Strategies
Published 2025-02-01“…Therefore, in this article, we propose that the cancer treatment process can be likened to an unequal game. …”
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356
KRAS and BRAF Mutation Detection: Is Immunohistochemistry a Possible Alternative to Molecular Biology in Colorectal Cancer?
Published 2015-01-01“…KRAS genotyping is mandatory in metastatic colorectal cancer treatment prior to undertaking antiepidermal growth factor receptor (EGFR) monoclonal antibody therapy. …”
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357
The prevalence and evidence-based management of needle fear in adults with chronic disease: A scoping review.
Published 2021-01-01“…<h4>Background</h4>Little is known about the prevalence and best management of needle fear in adults with chronic disease, who may experience frequent and long-term exposure to needles for lifesaving therapies such as renal dialysis and cancer treatment. Identifying interventions that assist in management of needle fear and associated distress is essential to support these patients with repeated needle and cannula exposure.…”
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358
Breast cancer classification based on hybrid CNN with LSTM model
Published 2025-02-01“…The speed-up process of detection and classification is crucial for effective cancer treatment. Medical image analysis methods and computer-aided diagnosis can enhance this process, providing training and assistance to less experienced clinicians. …”
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359
AR and YAP crosstalk: impacts on therapeutic strategies in prostate cancer
Published 2025-02-01“…Based on these findings, this paper investigates their significant roles in the onset, progression, and therapeutic resistance of prostate cancer, and discusses the clinical potential of YAP in prostate cancer treatment.…”
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360
Chemotherapy-related side effects in childhood cancer in Hiwa Hospital Sulaimani city/Kurdistan region, Iraq
Published 2019-09-01“…The side effects of chemotherapy in children are reported by cancer treatment teams; however, only little evidence is available on the routine clinical care. …”
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