Artificial intelligence in high-dose-rate brachytherapy treatment planning for cervical cancer: a review by Junyue Shi, Junyue Shi, Jun Chen, Gaokui He, Qinghe Peng

“…High-dose-rate brachytherapy (HDR-BT) is a critical component of cervical cancer treatment, requiring precise and efficient treatment planning. …”
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D-tryptophan triggered epithelial-mesenchymal transition by activating TGF-β signaling pathway by Chong Wang, Fangting Wang, Yanbo Wang, Linglin Fu

“…This study revealed the molecular mechanisms of D-tryptophan activity, provided D-tryptophan as a potential approach for cancer treatment, wound healing, organ development and other relevant applications.…”
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FDA-approved kinase inhibitors: a promising therapeutic avenue for traumatic brain injury by Dezhu Gao, Yu Shi, Zhiliang Wang, Weiming Liu

“…Nowadays, kinase inhibitors approved by the Food and Drug Administration (FDA) mainly for cancer treatment have shown potential effects in TBI. Preclinical studies suggest their potential in promoting recovery. …”
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ErbB4 as a Potential Molecular Target in the Treatment of Esophageal Squamous Cell Cancers by Ke Zhao, Bao-Jun Chen, Zhi-Guo Chen

“…Taken together, miRNA-140-5p could act as a potential molecular target in ErbB4 overexpressing ESCC cell lines paving the way for effective esophageal cancer treatment.…”
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Potential of Peroxisome Proliferator-Activated Receptor Gamma Antagonist Compounds as Therapeutic Agents for a Wide Range of Cancer Types by Jack D. Burton, David M. Goldenberg, Rosalyn D. Blumenthal

“…Since PPARγ antagonists represent a new drug class that holds promise as a broadly applicable therapeutic approach for cancer treatment, it is the subject of this review.…”
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Vitamin Bs as Potent Anticancer Agents through MMP-2/9 Regulation by Ha Vy Thi Vo, Namdoo Kim, Hyuck Jin Lee

“…In recent years, the role of coenzymes, particularly those from the vitamin B group in modulating the activity of metalloenzymes has garnered significant attention in cancer treatment strategies. Metalloenzymes play pivotal roles in various cellular processes, including DNA repair, cell signaling, and metabolism, making them promising targets for cancer therapy. …”
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A review of bismuth‐based nanoparticles and their applications in radiosensitising and dose enhancement for cancer radiation therapy by Daryoush Shahbazi‐Gahrouei, Yazdan Choghazardi, Arezoo Kazemzadeh, Paria Naseri, Saghar Shahbazi‐Gahrouei

“…Also, this review has highlighted the importance of bismuth‐based NPs in different forms of cancer treatment to find the highest efficiency for applying them as a suitable candidate for various cancer therapy and future clinical applications.…”
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Molecular techniques for cancer diagnostics by Vimal Kishor Singh, Ramesh Chandra

“…Recent advancements in describing genetic alterations in human cancers are a tempting reason for scientists to develop more effective, personalized therapies as the next level of cancer treatment. However, the drug discovery process is tedious, and getting approval from various regulatory authorities may be more frustrating for a steady developmental pace. …”
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Precise Construction of Dual-Promising Anticancer Drugs Associated with Gold Nanomaterials on Glioma Cancer Cells by P. Baby Shakila, Abdurahman Hajinur Hirad, Abdullah A. Alarfaj, Samer Hasan Hussein-Al-Ali, Beza Mulugeta

“…Multiple chemodrugs with nanotechnology have proven to be an effective cancer treatment technique. When taken combined, cabazitaxel (CTX) and cisplatin (PT) have more excellent cytotoxic effects than drugs used alone in the chemotherapy of several different cancers. …”
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Molecular Mechanism of Stem Cell Differentiation into Adipocytes and Adipocyte Differentiation of Malignant Tumor by Kexin Zhang, Xudong Yang, Qi Zhao, Zugui Li, Fangmei Fu, Hao Zhang, Minying Zheng, Shiwu Zhang

“…Understanding the molecular mechanism of adipogenesis and adipose differentiation of cancer cells may contribute to cancer treatments that involve inducing differentiation into benign cells.…”
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Mechanistic insights into the role of traditional Chinese medicine in treating gastric cancer by Ziqiang Chen, Ting Yu, Yunhe Wang, Jiaxin Li, Bo Zhang, Liya Zhou

“…The insights presented underscore the significant potential of TCM as an integral component of comprehensive gastric cancer treatment strategies, highlighting avenues for future research and clinical application to improve patient outcomes.…”
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Impact of frequent ARID1A mutations on protein stability provides insights into cancer pathogenesis by Rajen K. Goutam, Gangtong Huang, Exequiel Medina, Feng Ding, William J. Edenfield, Hugo Sanabria

“…This research paves the way for identifying and categorizing which ARID1A mutations are most pathogenic, potentially guiding the development of targeted therapies tailored to specific mutation profiles in cancer treatment.…”
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17α-Ethynyl-5α-androstane-3α, 17β-diol Treatment of MNU-Induced Mammary Cancer in Rats by Clarence N. Ahlem, James M. Frincke, Steven K. White, Christopher L. Reading, Richard J. Trauger, Rajkumar Lakshmanaswamy

“…These data warrant clinical investigation of HE3235 for breast cancer treatment.…”
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M2 Macrophages Mediate the Resistance of Gastric Adenocarcinoma Cells to 5-Fluorouracil through the Expression of Integrin β3, Focal Adhesion Kinase, and Cofilin by Daniel Ngabire, Irvine Niyonizigiye, Maheshkumar Prakash Patil, Yeong-Ae Seong, Yong Bae Seo, Gun-Do Kim

“…These results reveal that integrin β3, focal adhesion protein (FAK), and cofilin proteins are potential targets for the improvement of fluorouracil efficacy in gastric cancer treatment.…”
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Poly lactic‐co‐glycolic acid‐alginate nanocarrier for efficient drug delivery to liver cancer cells by Mahsa Hoseinzadeh, Mohammad Javad Mokhtari, Farshid Kafilzadeh, Javad Mohammadnejad, Yaghoob Taheri

“…These data have indicated that fabricated nanocarrier could be promising DDS against liver cancer and replace with conventional approaches in cancer treatment, like chemotherapy.…”
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Effect of Transplantation of Bone Marrow Derived Mesenchymal Stem Cells and Platelets Rich Plasma on Experimental Model of Radiation Induced Oral Mucosal Injury in Albino Rats by Basma Elsaadany, Samar El Kholy, Dalia El Rouby, Laila Rashed, Tarek Shouman

“…Normal tissue damage following radiotherapy is still a major problem in cancer treatment. Therefore, the current work aimed at exploring the possible role of systemically injected bone marrow derived mesenchymal stem cells (BM-MSCs) and/or locally injected platelet rich plasma (PRP) in ameliorating the side effects of ionizing radiation on the rat’s tongue. …”
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Targeting PPARγ Signaling Cascade for the Prevention and Treatment of Prostate Cancer by Sakshi Sikka, Luxi Chen, Gautam Sethi, Alan Prem Kumar

“…These TZD-derived novel therapeutic agents, alone or in combination with other anticancer drugs, have translational relevance in fostering effective strategies for cancer treatment. TZDs have been proven for antitumor activity in a wide variety of experimental cancer models, both in vitro and in vivo, by affecting the cell cycle, inducing cell differentiation and apoptosis, as well as by inhibiting tumor angiogenesis. …”
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Antioxidative and anticancer effects of Tacca chantrieri extract enhancing cisplatin sensitivity in cholangiocarcinoma cells. by Napat Armartmuntree, Yingpinyapat Kittirat, Bundit Promraksa, Watcharin Loilome, Hasaya Dokduang, Anchalee Techasen, Pahol Sansomchai, Malinee Thanee, Thomas O'Connor, Phutthida Kongthitilerd, Sureerat Padthaisong

“…Additionally, the study investigated whether the combined impact of TC extract and cisplatin on CCA cells enhanced cisplatin's efficacy as an anti-cancer treatment. Results indicated that ethanolic extracts from TC contained phenolic and flavonoid compounds with robust antioxidant activity. …”
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N7-methylguanosine modification in cancers: from mechanisms to therapeutic potential by Qihui Wu, Xiaodan Fu, Guoqian Liu, Xiaoyun He, Yimin Li, Chunlin Ou

“…This suggests that they may be novel therapeutic targets for cancer treatment. On the other hand, the aberrant expression of m7G modification-associated molecules is linked to clinicopathological characteristics, including tumour staging, lymph node metastasis, and unfavourable prognoses in patients with cancer, indicating their potential as tumour biomarkers. …”
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Characterization and Inhibitory Effects of Magnetic Iron Oxide Nanoparticles Synthesized from Plant Extracts on HeLa Cells by Bernard Owusu Asimeng, Emmanuel Nyankson, Johnson Kwame Efavi, Amartey Nii Amarkai, Gloria Pokuaa Manu, Elvis Tiburu

“…The findings show that the particles have a different inhibitory mechanism on HeLa cells ion transfer and are promising to be further exploited for cancer treatment.…”
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