TRIZ Theory and the Method of Cancer Document Selection for Chemical Complexes and Innovation Schemes of Meta-Analysis with Lymphomas as an Example by Yan Huiquan, Lyu Penghui, Wang Ling, Yu Zhiming

“…In the face of the growing incidence of malignant tumors (about 3.929 million, data issued in January 2019) and the death rate (about 2.338 million, data issued in January 2019) and the limitation of the application of informatics in cancer treatment, this paper tried to use TRIZ theory to deduce new ideas about cancer treatments, perform literature analysis on schemes, and make retrieval strategy for meta-analyses on cancer therapy. …”
Get full text

Unveiling the impact of CD133 on cell cycle regulation in radio- and chemo-resistance of cancer stem cells by Luyao Wu, Luyao Wu, Takanori Katsube, Xiaofei Li, Bing Wang, Yi Xie

“…The adaptation of malignancy to therapy presents a significant challenge in cancer treatment. The cell cycle plays a crucial role in regulating the evolution of radio- and chemo-resistance in tumor cells. …”
Get full text

The role of acetylation and deacetylation in cancer metabolism by Cuicui Wang, Xiaoxin Ma

“…In this review, we focus on discussing how acetylation and deacetylation regulate cancer metabolism, thereby highlighting the central role of these post‐translational modifications in metabolic reprogramming, and hoping to provide strong support for the development of novel cancer treatment strategies. Key points Protein acetylation and deacetylation are key regulators of metabolic reprogramming in tumour cells. …”
Get full text

Fertility Preservation in Female Patients with Cancer Part II: Royan Institute Clinical Practice Guideline for Girls and Women with Cancer; A Review Study by Azar Yahyaei, Esmat Mashhadi Meighani, Firouzeh Ghaffari

“…The formulation and execution of harmonized guidelines and policies concerning the provision of FPservices, inclusive of therapeutic strategies and standardization of procedures, are crucial to surmount disagreementsregarding the delivery of these therapeutic services and avert delays in cancer treatment. The matter of FP andthe methodology for managing the treatment and follow-up of cancer patients should be documented as a componentof their management guideline, thereby providing patients with clear recommendations on fertility preservation.In this manuscript, we provide a succinct overview of existing international guidelines history and referencecomprehensive networks of FP services for oncology patients. …”
Get full text

Mental Health in Urologic Oncology by Danyon Anderson, Abrahim N. Razzak, Matthew McDonald, David Cao, Jamal Hasoon, Omar Viswanath, Alan D. Kaye, Ivan Urits

“…In order to better accommodate patient’s mental health needs when undergoing GU cancer treatment, we recommend incorporation of mental health metrics such as questionnaires to assess early treatment of MHI, a greater emphasis on psychosocial support with the patient’s loved ones, peers, and healthcare team, alongside advising healthy habits such as exercise which has been shown to drastically reduce MHI incidence across all pathologies. …”
Get full text

PTEN Gene: A Model for Genetic Diseases in Dermatology by Corrado Romano, Carmelo Schepis

“…The involvement of PTEN function in melanoma and multistage skin carcinogenesis, with its implication in cancer treatment, and the role of front office in diagnosing PHTS are the main reasons why the dermatologist should know about PTEN.…”
Get full text

Prognostic significance of ımmunhistochemical axl expression in pancreas ductal adenocarcinomas by Ozden Oz, Asuman Argon, Tulu Ayata Kebat, Ozlem Ozdemir, Savas Yakan

“…Axl is a receptor of the TKR family, and it has come to the fore in cancer treatment in the last decade. This study aimed to investigate the relationship of immunohistochemical Axl expression with histological features and its prognostic importance in PDACs. …”
Get full text

Clinical characteristics, diagnosis, treatment, and prognosis of Atezolizumab-induced encephalitis, aseptic meningitis or meningoencephalitis by Qingzi Yan, Yixiang Hu, Xiang Liu, Hong Xia

“…ObjectiveImmune checkpoint inhibitors (ICIs) have revolutionized cancer treatment and expanded the range of tumor indications. …”
Get full text

Chemotherapy as a Remedy to Gynaecological Cancers: Challenges and Coping Patterns Among Young Women by Titilayo Omolekan, Gbemisola Bolanle Ogbeye, Risikat Idowu Fadare

“…Chemotherapy is one of the cancer treatment modalities the side effects of which might affect young womens sexuality and functional status. …”
Get full text

Cancer-associated fibroblasts in carcinogenesis by Shufen Zhou, Zekun Zhao, Zhaojun Wang, Hanzheng Xu, Yijie Li, Ke Xu, Wei Li, Jiahua Yang

“…Ultimately, our aim is to contribute to the development of novel therapeutic strategies for cancer treatment.…”
Get full text

Extensive Morphea Following Adjuvant Radiotherapy for Breast Carcinoma—Case Report by Alexandru Panaitescu, Hannah Nguyen, Laurence Masson-Côté, Carolina Lucena Fernandes

“…Radiation-induced morphea (RIM) is a rare complication following radiotherapy (RT) for breast cancer treatment. Its distribution is usually confined to the breast having received radiotherapy. …”
Get full text

Targeting Bone Metabolism in Patients with Advanced Prostate Cancer: Current Options and Controversies by Tilman Todenhöfer, Arnulf Stenzl, Lorenz C. Hofbauer, Tilman D. Rachner

“…In patients with cancer-treatment induced bone loss (CTIBL), antiresorptive agents have been shown to improve bone mineral density (BMD) and to reduce the risk of fractures. …”
Get full text

Protocol to identify small-molecule inhibitors against cancer drug resistance by Juan Wei, She-Yu Zhang, Xue-Yuan Zhou, Yong Wei, Hao-Ran Jia, Qin Wu, Weihong Tan

“…Summary: Drug resistance has emerged as a critical challenge in clinical cancer treatment. Here, we present a high-throughput screening protocol to identify therapeutic small-molecule inhibitors against drug-resistant cancer cells. …”
Get full text

Sirt3 Regulates Response to Oxidative Stress by Interacting with BER Proteins in Colorectal Cancer by J. Kabzinski, A. Walczak, I. Majsterek

“…Using the knowledge obtained in the course of conducted experiments, we postulate consideration of Sirt3 as a target in the rising vulnerability of cancer cells during therapy and therefore increasing the effectiveness of cancer treatment.…”
Get full text

Emerging Lung Cancer Therapeutic Targets Based on the Pathogenesis of Bone Metastases by Moses O. Oyewumi, Adnan Alazizi, Daniel Wehrung, Rami Manochakian, Fayez F. Safadi

“…It is anticipated that the information gathered might be useful in future efforts of optimizing lung cancer treatment strategies.…”
Get full text

Cytotoxicity of Nanocarrier-Based Drug Delivery in Oral Cancer Therapy: A Systematic Review and Meta-Analysis by Mohammad A. Saghiri PhD, Ravinder S. Saini PhD, Artak Heboyan PhD

“…Conclusion Nanocarrier-based drug delivery has been found to be a superior approach compared to drug delivery in free form, increasing the efficacy and safety of oral cancer treatment.…”
Get full text

Opportunities and challenges of immuno-oncology: A bibliometric analysis from 2014 to 2023 by Siqi Zhang, Lina Miao, Xiaoxia Tian, Bingxu Yang, Baoping Luo

“…The emergence of immuno-oncology (IO) has led to revolutionary changes in the field of cancer treatment. Despite notable advancements in this field, a thorough exploration of its full depth and extent has yet to be performed. …”
Get full text

Pain and Frailty in Childhood Cancer Survivors: A Narrative Review by Chiara Papini, Jaspreet K. Sodhi, Cassie M. Argenbright, Kirsten K. Ness, Tara M. Brinkman

“…A significant proportion of childhood cancer survivors experience persistent health problems related to cancer or cancer treatment exposures, including accelerated or early onset of aging. …”
Get full text

Iron oxide nanoparticles coated with bioactive materials: a viable theragnostic strategy to improve osteosarcoma treatment by Amy Sarah Benjamin, Sunita Nayak

“…A significant innovation in this area is the use of nanotechnology, specifically nanoparticles, to tackle various challenges in cancer treatment. Iron oxide nanoparticles stand out in both therapeutic and diagnostic applications, offering a versatile platform for targeted drug delivery, hyperthermia, magneto-thermal therapy, and combinational therapy using modulation of ferroptosis pathways. …”
Get full text

Bioinformatic Analysis of PTTG Family and Prognosis and Immune Cell Infiltration in Gastric Cancer by Xiao Li, Yanghao Tai, Shuying Liu, Yating Gao, Kaining Zhang, Jierong Yin, Huijuan Zhang, Xia Wang, Xiaofei Li, Dongfeng Zhang

“…Difficulties and future prospects of immunotherapy in cancer treatment. Adaptive cell therapy, cancer vaccines, gene therapy, and monoclonal antibody therapy have all been used in gastric cancer with some initial success. …”
Get full text