Genetic advancements in breast cancer treatment: a review by Marzieh Shokoohi, Sadaf Sedaghatshoar, Homaira Arian, Milad Mokarami, Fatemeh Habibi, Fatemeh Bamarinejad

“…Abstract Breast cancer (BC) remains a leading cause of cancer-related deaths among women globally, highlighting the urgent need for more effective and targeted therapies. …”
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Obesity Is Associated with Early Onset of Gastrointestinal Cancers in California by Yen-Yi Juo, Melinda A. Maggard Gibbons, Erik Dutson, Anne Y. Lin, Jane Yanagawa, O. Joe Hines, Guido Eibl, Yijun Chen

“…Although it is well known that obesity is a risk factor for gastrointestinal (GI) cancer, it is not well established if obesity can cause earlier GI cancer onset. …”
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Pancreatic Cancer: Molecular, Biochemical, Chemopreventive, and Therapeutic Aspects by Juan Iovanna, José Luis Neira

“…Pancreatic cancer (PC) is the fourth leading cause of cancer death, with a median survival of 6 months and a dismal 5-year survival rate of 35%, a figure which has remained relatively unchanged over the past 25 years. …”
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Integrated analysis of cell cycle and p53 signaling pathways related genes in breast, colorectal, lung, and pancreatic cancers: implications for prognosis and drug sensitivity for... by Jiyauddin Khan, Priyanjana Ghosh, Urmi Bajpai, Kountay Dwivedi, Daman Saluja

“…Abstract Cancer, a leading cause of death worldwide, is projected to increase by 76.6% in new cases and 89.7% in mortality by 2050 (WHO 2022). …”
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Small Bowel Intussusception due to Metastasized Sarcomatoid Carcinoma of the Lung: A Rare Cause of Intestinal Obstruction in Adults by Ali Guner, Savaş Karyagar, Ayten Livaoglu, Can Kece, Uzer Kucuktulu

“…Sarcomatoid carcinoma, a very rare subtype of lung cancer, rarely metastasizes to small bowel and causes complications. …”
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Hemostatic Interventions and All-Cause Mortality in Hemodynamically Unstable Pelvic Fractures: A Systematic Review and Meta-Analysis by XuWen Zheng, MaoBing Chen, Yi Zhuang, Jin Xu, Liang Zhao, YongJun Qian, WenMing Shen, Ying Chu

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Cancer-associated fibroblast-derived COL17A1 promotes gemcitabine resistance and tumorigenesis in pancreatic cancer cells by interacting with ACTN4 by Rongyu Shi, Ning Zhang, Han Li, Hu Zhong, Chengcheng Zhong, Wei Du, Xi Yang

“…Pancreatic cancer (PC) is a leading cause of cancer mortality with high aggressiveness. …”
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Small Bowel Adenocarcinoma as the Cause of Gastrointestinal Bleeding in Celiac Disease: A Rare Malignancy in a Common Disease by Jaleh Fallah, Maxwell Eyram Afari, Alfredo C. Cordova, Adam J. Olszewski, Taro Minami

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Association of dietary intake with cancer of the digestive system: a cross-sectional study by Xinxin Qin, Litao Ge, Song Wu, Wei Li

“…BackgroundIn recent years, the incidence of cancers of the digestive system has been increasing, posing a severe threat to the lives and health of people around the world, and has become one of the leading causes of cancer deaths worldwide. …”
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Development and validation of a prediction model for all-cause mortality in maintenance dialysis patients: a multicenter retrospective cohort study by Jingcan Wu, Xuehong Li, Hong Zhang, Lin Lin, Man Li, Gangyi Chen, Cheng Wang

“…The discrimination and accuracy of the prediction model were assessed using C-indexes and calibration curves, while the clinical value was assessed by decision curve analysis (DCA).Results The best predictors of 1-, 3-, and 5-year all-cause mortality contained nine independent factors, including age, body mass index (BMI), diabetes mellitus (DM), cardiovascular disease (CVD), cancer, urine volume, hemoglobin (HGB), albumin (ALB), and pleural effusion (PE). …”
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Coal Worker's Pneumoconiosis Mimicking Lung Cancer in a 75‐Year‐Old Woman With a History of Breast Cancer: A Clinical Case Report by Yeganeh Pakbaz, Farzan Moodi

“…We present a case of CWP in a 75‐year‐old female with a history of breast cancer, initially suspected of lung cancer due to an incidental mass on chest radiography. …”
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Emerging Nanoparticle-Based Diagnostics and Therapeutics for Cancer: Innovations and Challenges by Rachitha Puttasiddaiah, Nagaraj Basavegowda, Nityashree Kyathegowdanadoddi Lakshmanagowda, Vinay Basavegowda Raghavendra, Niju Sagar, Kandi Sridhar, Praveen Kumar Dikkala, Maharshi Bhaswant, Kwang-Hyun Baek, Minaxi Sharma

“…Chemotherapy, radiation, and surgery are the three main methods of treating cancer. These methods seek to completely eradicate all cancer cells while having the fewest possible unintended impacts on healthy cell types. …”
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The multidisciplinary approach in perioperative management of senile patients with colorectal cancer by D. V. Markar'yan, V. V. Nikoda, P. V. Tsarkov

“…To present data on surgical treatment of patients of senile age with colorectal cancer, to estimate principal causes of unsatisfactory results.Original positions. …”
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Current Strategies for Cancer Management: an Analysis of Therapeutic and Prevention Options by Carlos David Castañeda Guillot, Ronelsys Martínez Martínez, Fernando de Jesús Castro Sánchez

“…Cancer as the first cause of mortality represents a challenge for the scientific community, therefore, it is important to know and implement preventive measures and diagnostic means to reduce its prevalence.…”
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Genetic and Molecular Biology Implications in the Surgical Treatment of Gastric Cancer by Roberto Eduardo Aguirre Fernández, Miguel Ángel Serra Valdés

“…Gastric cancer is one of the leading causes of death from neoplasms in the world. …”
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Active Surveillance for Localized Prostate Cancer – Current Practices and Recommendations by Jennifer N. Wu, Marc A. Dall'Era

“…Prostate cancer autopsy studies show the uniquely high prevalence rates of small, indolent tumors in men dying of other causes. …”
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Genetic and Biochemical Alterations in Non-Small Cell Lung Cancer by Jackie L. Johnson, Smitha Pillai, Srikumar P. Chellappan

“…Despite significant advances in the detection and treatment of lung cancer, it causes the highest number of cancer-related mortality. …”
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Increased Vitamin B12 Levels in Patients with Oral Cancer by Prashant Gupta, Subhash Chandra, Awanindra Kumar Jha, Tanya Khaitan, Anjani Kumar Shukla, Shantala R Naik

“…Background: Oral cancer (OC), which happens to be one of the leading causes of death in the Indian population, is caused primarily by tobacco use, although other factors are also responsible. …”
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The Role of Mitochondrial NADPH-Dependent Isocitrate Dehydrogenase in Cancer Cells by Katarína Smolková, Petr Ježek

“…Reductive carboxylation of 2-oxoglutarate by IDH2 (in the reverse Krebs cycle direction), which consumes NADPH, may follow glutaminolysis of glutamine to 2-oxoglutarate in cancer cells. When the reverse aconitase reaction and citrate efflux are added, this overall “anoxic” glutaminolysis mode may help highly malignant tumors survive aglycemia during hypoxia. …”
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Relationship between neutropenia caused by nanoliposomal irinotecan/fluorouracil/leucovorin and treatment outcomes in the NAPOLEON-2 study (NN-2301) by Tomonori Araki, Yuki Sonoda, Mototsugu Shimokawa, Taiga Otsuka, Kohei Hayashi, Takuya Honda, Kazuhiko Nakao, Taro Shibuki, Junichi Nakazawa, Shiho Arima, Keisuke Miwa, Yoshinobu Okabe, Futa Koga, Yujiro Ueda, Yoshihito Kubotsu, Hozumi Shimokawa, Shigeyuki Takeshita, Azusa Komori, Kazuo Nishikawa, Satoshi Otsu, Ayumu Hosokawa, Hisanobu Oda, Tatsunori Sakai, Shuji Arita, Machiko Kawahira, Hiroki Taguchi, Kengo Tsuneyoshi, Yasunori Kawaguchi, Toshihiro Fujita, Takahiro Sakae, Tsuyoshi Shirakawa, Toshihiko Mizuta, Kenji Mitsugi

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