Ginkgolide B Blocks Vascular Remodeling after Vascular Injury via Regulating Tgfβ1/Smad Signaling Pathway by Quan Wang, Shuai Ni, Li Ling, Siqi Wang, Hanbin Xie, Zhanhong Ren

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Thiazolidinediones and Edema: Recent Advances in the Pathogenesis of Thiazolidinediones-Induced Renal Sodium Retention by Shoko Horita, Motonobu Nakamura, Nobuhiko Satoh, Masashi Suzuki, George Seki

“…However, TZDs have side effects, such as edema, congestive heart failure, and bone fracture, and may increase bladder cancer risk. Edema and heart failure, which both probably originate from renal sodium retention, are of great importance because these side effects make it difficult to continue the use of TZDs. …”
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PAIVS: prediction of avian influenza virus subtype by Hyeon-Chun Park, Juyoun Shin, Sung-Min Cho, Shinseok Kang, Yeun-Jun Chung, Seung-Hyun Jung

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Whole-Body 18FDG-PET in an Arthritis Paraneoplastic Syndrome Revealed an Underlying Hematological Neoplasm by Serge Cammilleri, Marie Caroline Guzian, Jean-Pierre Mattei, Olivier Mundler, Sandrine Guis

“…The use of the 18FDG-PET can help to detect earlier hematological neoplasm in cases of paraneoplastic syndrome without a determined cause and to treat more rapidly and specifically the patient.…”
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Habitual khat chewing induced oral erythroplakia: A case report by Aisha A.H. Al-Jamaei, Khaled Al-Kebsi, ElhamA. Al-Qafaf, Mayada H.M. Hanash, R.V. Subramanyam, Jan G.A.M. de Visscher

“…It has a high and significant risk of malignant transformation. OE is most commonly caused by tobacco use, especially smokeless tobacco, alcohol drinking, and chewing betel nut. …”
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Detection of composition of functional component theabrownins in Pu-erh tea by degradation method by Simin Hu, Xiaolei Li, Chuangchuang Gao, Xianyu Meng, Mingchao Li, Yuqian Li, Tianrui Xu, Qian Hao

“…Habitual tea consumption can reduce the risk of ASCVD morbidity and mortality and all-cause mortality in China, and long-term adherence to this habit can provide greater protection. …”
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Holding the Inflammatory System in Check: TLRs and Their Targeted Therapy in Asthma by Zhiyong Dong, Lingxin Xiong, Weijie Zhang, Peter G. Gibson, Ting Wang, Yanjiao Lu, Guoqiang Wang, Hui Li, Fang Wang

“…Inflammation plays a protective role in removing pathogenic factors, but dysregulated inflammation is associated with several major fatal diseases such as asthma, cancer, and cardiovascular diseases. Asthma is a complex heterogenous disease caused by genetic and environmental factors. …”
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A review of research progress on disease burden of foodborne aflatoxins by Mei QIN, Jinyao CHEN, Lishi ZHANG, Jiao HUO, Yang SONG, Li CHENG

“…The International Agency for Research on Cancer (IARC) has classified AFB1, AFB2, AFG1 and AFG2 as Group 1 carcinogens, primarily causing hepatocellular carcinoma (HCC) in humans, but also affecting growth and development in children and damaging the human immune system, resulting in varying degrees of health burden to populations. …”
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Alcohol induces α2‐6sialo mucin O‐glycans that kill U937 macrophages mediated by sialic acid‐binding immunoglobulin‐like lectin 7 (Siglec 7) by Pi‐Wan Cheng, Vishwanath‐Reddy Hothpet, Ganapati Bhat, Kristina Bailey, Lei Li, Derrick R. Samuelson

“…Alcohol misuse increases infections and cancer fatalities, but mechanisms underlying its toxicity are ill‐defined. …”
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Schiff bases and their possible therapeutic applications: A review by Nidhi, Siddharam, Devendra Pratap Rao, Amit Kumar Gautam, Ashish Verma, Yashveer Gautam

“…Schiff base, however, is suspected of causing cancer and can cause severe eye discomfort.…”
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A Gel Formulation Containing a New Recombinant Form of Manganese Superoxide Dismutase: A Clinical Experience Based on Compassionate Use-Safety of a Case Report by Lucia Grumetto, Antonio Del Prete, Giovanni Ortosecco, Antonella Borrelli, Salvatore Del Prete, Aldo Mancini

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Etanercept Attenuates Traumatic Brain Injury in Rats by Reducing Brain TNF-α Contents and by Stimulating Newly Formed Neurogenesis by Chong-Un Cheong, Ching-Ping Chang, Chien-Ming Chao, Bor-Chih Cheng, Chung-Zhing Yang, Chung-Ching Chio

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A Case of De Novo CD5+ Disseminated Intravascular Large B-Cell Lymphoma Presenting as Multiorgan Failure by Daulath Singh, Devika Kapuria, Suparna Nanua, Rakesh Gaur

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Triple-drug antibiotic therapy for disseminated nocardial abscess in the mediastinum and brain of an immunocompetent patient: a case report by Yue Zhang, Zhongchun Qi, Hua Li, Hui Gao

“…Conclusions Mediastinal nocardiosis with disseminated brain abscesses is a rare condition that can be difficult to differentiate from brain metastases caused by lung cancer. Bacterial culture results, imaging features, and MDT discussions are crucial for accurate diagnosis and treatment. …”
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Role of Microbes and Nanomaterials in the Removal of Pesticides from Wastewater by Arpita Roy, Madhura Roy, Saad Alghamdi, Anas S. Dablool, Angham Ahmed Almakki, Ismat H. Ali, Krishna Kumar Yadav, Md. Rabiul Islam, Marina M. S. Cabral-Pinto

“…Long-term exposure to pesticides can cause neurological disorders, reproductive complications, cancer, immunological, and pulmonary diseases. …”
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Progesterone Increases Apoptosis and Inversely Decreases Autophagy in Human Hepatoma HA22T/VGH Cells Treated with Epirubicin by Wen-Tsan Chang, Hsiao-Ling Cheng, Bau-Shan Hsieh, Chien-Chih Chiu, King-Teh Lee, Kee-Lung Chang

“…Hepatocellular carcinoma (HCC) is the leading cause of cancer-related deaths worldwide. Epirubicin can induce intracellular reactive oxygen species and is widely used to treat unresectable HCC. …”
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Phylostratigraphic analysis of gene networks of human diseases by Z. S. Mustafin, S. A. Lashin, Yu. G. Matushkin

“…It was also shown that among the gene networks analyzed, the highest proportion of evolutionarily young genes was found in the networks associated with diseases of the immune system (65 %), and the highest proportion of evolutionarily ancient genes was found in the networks responsible for the formation of human dependence on substances that cause addiction to chemical compounds (88 %); gene networks responsible for the development of infectious diseases caused by parasites are signif icantly enriched for evolutionarily young genes, and gene networks responsible for the development of specif ic types of cancer are signif icantly enriched for evolutionarily ancient genes.…”
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Improved Clinical Outcomes with Appropriate Meropenem De-escalation in Patients with Febrile Neutropenia by Tyler Luu, Austin Fan, Reid Shaw, Hina Dalal, Jenna Adams, Maressa Santarossa, Gail Reid, Stephanie Tsai, Nina M. Clark, Fritzie S. Albarillo

“…Introduction: Antibiotic stewardship is a critical aspect of managing cancer patients with febrile neutropenia (FN) to limit the development of drug-resistant organisms and minimize adverse drug effects. …”
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Pseudomyxoma Peritonei Originating from Transverse Colon Mucinous Adenocarcinoma: A Case Report and Literature Review by Yingbo Gong, Xin Wang, Zhi Zhu

“…There have been no reports of PMP originating from a transverse colonic mucinous adenocarcinoma and causing metastatic mucinous adenocarcinoma. Case Presentation. …”
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Drug repurposing screen for the rare disease ataxia-telangiectasia by Namrata Jayanth, Gurvan Mahé, Matthew Campbell, Mike Lipkin, Shushant Jain, Rhea van de Bospoort, Jennifer Thornton, Brad Margus, David F. Fischer

“…Ataxia Telangiectasia (A-T) is a rare, autosomal recessive genetic disorder characterized by a variety of symptoms, including progressive neurodegeneration, telangiectasia, immunodeficiency, and an increased susceptibility to cancer. It is caused by bi-allelic mutations impacting a gene encoding a serine/threonine kinase ATM (Ataxia Telangiectasia Mutated), which plays a crucial role in DNA repair and maintenance of genomic stability. …”
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