Nonfamilial Juvenile Polyposis Syndrome with Exon 5 Novel Mutation in SMAD 4 Gene by Amna Ahmed, Badr Alsaleem

“…Juvenile polyposis syndrome (JPS) is a rare autosomal dominant hereditary disorder, characterized by multiple juvenile polyps in the gastrointestinal tract and an increased risk of colorectal cancer. JPS is most frequently caused by mutations in the SMAD4 or BMPR1A genes. …”
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The US perspective on e-cigarettes and harm reduction by Mitch Zeller

“…And that’s significant because while there are misperceptions about the safety of nicotine, the reality is that nicotine does not directly cause the cancer, the lung disease and the heart disease associated with the use of cigarettes and other combustible products. …”
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Spontaneous Pneumomediastinum from Running Sprints by Joseph W. Turban

“…Spontaneous pneumomediastinum (SPM) is a fairly rare condition, caused by increased intrathoracic pressure, leading to free air in the mediastinal structures. …”
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Direct-Acting Oral Anticoagulants in the Management of Cerebral Venous Sinus Thrombosis—Where Do We Stand? by Nikhil Vojjala, Supriya Peshin, Lakshmi Prasanna Vaishnavi Kattamuri, Rabia Iqbal, Adit Dharia, Jayalekshmi Jayakumar, Rafi Iftekhar, Shagun Singh, Mamtha Balla, Claudia S. Villa Celi, Ramya Ramachandran, Rishab Prabhu, Sumeet K. Yadav, Geetha Krishnamoorthy, Vijendra Singh, Karan Seegobin

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Consensus on rapid screening for prodromal Alzheimer’s disease in China by Yao Lu, Ying Wang, Jianping Jia, Qihao Guo, Ya Miao, Lin Huang, Xiaochun Chen, Qinjie Li, Fengfeng Pan, Liang Cui, Tianlu Chen, Yatian Li, Jingnan Wu

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Treatment of chronic hepatitis B: options, monitoring, special cases and adverse effects by Mateusz Litwin Litwin, Agnieszka Mikosińska, Jakub Parys, Patrycja Kałuziak, Aleksandra Witek, Martyna Kaźmierczak, Stanisław Jesionek, Marta Jajczak, Maciej Mossakowski

“…Chronic hepatitis B virus (HBV) infection affects approximately 296 million people worldwide and is the leading cause of cirrhosis and liver cancer globally. HBV-related cirrhosis resulted in an estimated 331,000 deaths in 2019, and it is estimated that the number of deaths from HBV-related liver cancer in 2019 was 192,000, an increase from 156,000 in 2010. …”
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Health benefits of pedestrian and cyclist commuting: evidence from the Scottish Longitudinal Study by Paul Kelly, David Walsh, Bruce Whyte, Zhiqiang Feng, Chris Dibben, Graham Baker, Ruth Dundas, Evangelia Demou, Catherine Friel

“…Cox proportional hazard models were used to compare cyclist and pedestrian commuters with non-active commuters for a range of health outcomes, controlling for pre-existing health conditions, and demographic and socioeconomic characteristics.Results Compared with non-active commuting, cyclist commuting was associated with lower all-cause mortality risk (HR 0.53, 95% CI 0.38 to 0.73), lower risk of any hospitalisation (HR 0.90, 95% CI 0.84 to 0.97), lower risk of cardiovascular disease (CVD) hospitalisation (HR 0.76, 95% CI 0.64 to 0.91) and of having a CVD prescription (HR 0.70, 95% CI 0.63 to 0.78), lower risk of cancer mortality (HR 0.49, 95% CI 0.30 to 0.82) and cancer hospitalisation (HR 0.76, 95% CI 0.59 to 0.98), and lower risk of having a prescription for mental health problems (HR 0.80, 95% CI 0.73 to 0.89). …”
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Loss of SMAD1 in acute myeloid leukemia with KMT2A::AFF1 and KMT2A::MLLT3 fusion genes by Lisa Dietsche, Kristin Stirm, Veronika Lysenko, Corina Schneidawind, Alexandar Tzankov, Anne Müller, Alexandre P. A. Theocharides

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Formaldehyde Content in Indonesian Food and the Analysis Method: A Review by Anggita Rosiana Putri, Kevin Awidarta, Bachtiar Rifai Pratita Ihsan, Intan Khaerunisa, Muhammad Bachrul Ulum, Laili Fadhotun Huda

“…Formaldehyde has the potential to cause cancer. In recent years, formaldehyde has still been found in several Indonesian foods. …”
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METTL10 attenuates adriamycin-induced podocyte injury by targeting cell dedifferentiation by Jiwen Bao, Ziyang Li, Huanzhen Yao, Bei Wu, Leyi Gu, Yangbin Pan, Ling Wang

“…Podocyte damage is a hallmark of glomerular diseases including focal segmental glomerulosclerosis (FSGS) and one of the leading causes of CKD. Lysine methylation is a crucial post-translational modification. …”
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Radioprotective Effect of Selenium Nanoparticles: A Mini Review by Rasool Azmoonfar, Masoud Moslehi, Daryoush Shahbazi-Gahrouei

“…However, ionizing radiation can cause damage to healthy cells and tissues, leading to side effects and an increased risk of cancer and other diseases over time. …”
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Correlation between microRNA-21 expression and overweight/obesity by Shashwat Sinha, Babu Rajendran, Shomnath Vasagam, Jeyakumar Balakrishnan

“…Recent studies have proven that microRNA-21 causes the systemic hypertension, many cardiac pathologies, and some cancers. …”
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Multiple Myeloma in a Patient with ANKRD26-Related Thrombocytopenia Successfully Treated with Combination Therapy and Autologous Stem Cell Transplant by Muhammad Husnain, Trent Wang, Maikel Valdes, James Hoffman, Lazaros Lekakis

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A Rare Case of Metastatic Hepatocellular Carcinoma Masquerading as a Forehead Hematoma by Kimberly Sanders, Ashley Thomas, Carmen Isache, Anwer Siddiqi

“…Hepatocellular carcinoma (HCC) is the most common primary liver cancer and can arise from any form of chronic liver disease or cirrhosis. …”
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Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects by Bharti Sharma, Sudeep Shukla, Rohit Rattan, Musarrat Fatima, Mayurika Goel, Mamta Bhat, Shruti Dutta, Rakesh Kumar Ranjan, Mamta Sharma

“…The rise in antimicrobial resistance is a cause of serious concern since the ages. Therefore, a dire need to explore new antimicrobial entities that can combat against the increasing threat of antibiotic resistance is realized. …”
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Severe Mitral Regurgitation–Induced Acute Heart Failure due to Nonbacterial Thrombotic Endocarditis in a Patient With Urothelial Carcinoma Recurrence by Catarina Santos Reis, Francisco Dias, Bárbara Granja, Maria Inês Matos, Ana Ribeiro, Fernando Friões

“…It is related with systemic embolic phenomena occurring predominantly in advanced cancer stages, particularly adenocarcinomas. It is a diagnosis of exclusion based on the clinical context, echocardiographic findings of a vegetation, and negative blood cultures, and distinction between infective endocarditis is challenging. …”
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Role of ferroptosis in atrial fibrillation: a review by Shaowei Fan, Yuanhui Hu, Jingjing Shi

“…Cardiovascular disease remains the leading cause of mortality, with atrial fibrillation emerging as one of the most common conditions encountered in clinical practice. …”
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Primary Malignancy in a Supernumerary Testicle Presenting as a Large Pelvic Mass by Justin Noroozian, Daniel Farishta, Daniel Ballow, Joseph Sonstein, Eduardo Orihuela, Eduardo Eyzaguirre

“…Another condition of the testes is seminoma, a common cause of testicular germ cell tumor. A 35-year-old male was transferred to our hospital with a diagnosis of abdominal mass causing abdominal pain. …”
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Invagination of the Adductor Loop of the Small Intestine into the Lumen of the Gastric Stump after Pancreatoduodenal Resection by G. V. Balitsky, V. M. Legostaev, T. V. Zema

“…The patient also reported an episode of black stools 7 years after pancreatoduodenal resection for pancreatic head cancer and 3 years after reconstructive surgery by performing choledochoenteroanastomosis. …”
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Persistent Hypoglycemia in Patient with Hodgkin’s Disease by Harold Cinco Lim, Lubna Bashir Munshi, David Sharon

“…Several case reports strengthen the hypothesis of an insulin-like growth factor or antibodies secreted by the cancer cells causing hypoglycemia in Hodgkin’s disease but none of them have been confirmed. …”
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