pir-hsa-216911 inhibit pyroptosis in hepatocellular carcinoma by suppressing TLR4 initiated GSDMD activation by Zhouxiang Liao, Lichao Yang, Xiaojing Cheng, Xuejing Huang, Qi Zhang, Daoqiang Wen, Zhenyu Song, Yasi Li, Sha Wen, Yongfeng Li, Meizhen Ou, Zhangnan Huang, Tianqi Liu, Min He

“…Abstract Hepatocellular carcinoma (HCC) is a global health concern, ranking as the fourth leading cause of cancer-related deaths worldwide. However, the role of piwi-interacting RNAs (piRNAs) in HCC processes has not been extensively explored. …”
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M cells targeted H. pylori antigen SAM-FAdE displayed on bacterium-like particles induce protective immunity by Furui Zhang, Jiale Chen, Zhen Zhang, Jing Wu, Yuliang Qu, Linhan Ni, Guolin Zhang, Kunmei Liu, Le Guo

“…Abstract Background Helicobacter pylori (H. pylori), a specific bacterium capable of surviving in the acidic environment of the stomach, has been recognized as a group of causative agents of gastric cancer. Therefore, the development of mucosal vaccines against H. pylori is expected to provide an important direction for the treatment of chronic gastritis and the prevention of gastric cancer. …”
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Laboratory diagnosis of H. pylori among dyspeptic patients using Culture and Rapid urease test by Hogir Mohammed Shukri Saadi, Ali Yahya Saeed

“…Globally Helicobacter pylori has been defined is the prime reason of stomach ulcer and gastric cancer. Medical laboratory analysis of H. pylori infection is done by two ways invasive and non- invasive methods. …”
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Shared rare genetic variants in multiplex autism families suggest a social memory gene under selection by Kang Seon Lee, Taeyeop Lee, Mujun Kim, Elizaveta Ignatova, Hyo-Jeong Ban, Min Kyung Sung, Younghoon Kim, Youn-Jae Kim, Jin-Hee Han, Jung Kyoon Choi

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Longitudinal functional outcomes and late effects of radiation following treatment of nasopharyngeal carcinoma: secondary analysis of a prospective cohort study by Gia Gill, Ciaran Lane, Candace Myers, Evan D. Kerr, Pascal Lambert, Andrew Cooke, Paul D. Kerr

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A dynamic co-expression approach reveals Gins2 as a potential upstream modulator of HNSCC metastasis by Nasibeh Khayer, Samira Shabani, Maryam Jalessi, Mohammad Taghi Joghataei, Frouzandeh Mahjoubi

“…Abstract Head and neck squamous cell carcinoma (HNSCC) is an aggressive cancer that is notably associated with a high risk of lymph node metastasis, a major cause of cancer mortality. …”
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A Review on Bioactive Phytochemical Constituents and Pharmacological Activities of Aegiceras corniculatum: A Pharmaceutically Important Mangrove Plant by Pritam Sarkar, Tasfiya Rufaidah Ahnaf, Razina Rouf, Jamil Ahmad Shilpi, Shaikh Jamal Uddin

“…These phenolic chemicals also reduce oxidative stress and help treat cancer and other inflammatory diseases. The extract of this plant activates the κ-opioid receptor, causing central antinociception. …”
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Phytochemical analysis and biological activities of solvent extracts and silver nanoparticles obtained from Woodwardia unigemmata (Makino) Nakai. by Syed Ahsan Shah, Alia Gul, Ghulam Mujtaba Shah, Maha Saeed Ibrahim Wizrah, Awais Khalid, Mamoona Munir, Zainab Maqbool, Arusa Aftab, Mazen R Alrahili, Ayesha Siddiqua, M Yasmin Begum

“…Multidrug resistant bacteria are causing health problems and economic burden worldwide; alternative treatment options such as natural products and nanoparticles have attained great attention recently. …”
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Predictors and Significance of Readmission after Esophagogastric Surgery: A Nationwide Analysis by Richard PT Evans, MBBS, FRCS, Sivesh K Kamarajah, MBChB, MRCS, Felicity Evison, MSc, Xiaoxu Zou, PhD, Ben Coupland, MSci, Ewen A Griffiths, MD, FRCS

“…The aim of this study is to identify risk factors for readmission after elective esophagogastric cancer surgery and characterize the impact of readmission on long-term survival. …”
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Computer-Aided Design of an Epitope-Based Vaccine against Epstein-Barr Virus by Julio Alonso-Padilla, Esther M. Lafuente, Pedro A. Reche

“…EBV replicates in epithelial and B cells and causes infectious mononucleosis. EBV infection is also linked to various cancers, including Burkitt’s lymphoma and nasopharyngeal carcinomas, and autoimmune diseases such as multiple sclerosis. …”
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Bortezomib-releasing silica-collagen xerogels for local treatment of osteolytic bone- and minimal residual disease in multiple myeloma by Dirk Hose, Seemun Ray, Sina Rößler, Ulrich Thormann, Reinhard Schnettler, Kim de Veirman, Thaqif El Khassawna, Christian Heiss, Anne Hild, Daniel Zahner, Francisca Alagboso, Anja Henss, Susanne Beck, Martina Emde-Rajaratnam, Jürgen Burhenne, Juliane Bamberger, Eline Menu, Elke de Bruyne, Michael Gelinsky, Marian Kampschulte, Marcus Rohnke, Sabine Wenisch, Karin Vanderkerken, Thomas Hanke, Anja Seckinger, Volker Alt

“…Abstract Background Accumulation of malignant plasma cells in the bone marrow causes lytic bone lesions in 80% of multiple myeloma patients. …”
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Hepatocellular Carcinoma: Consensus, Controversies and Future Directions: A Report from the Canadian Association for the Study of the Liver Hepatocellular Carcinoma Meeting by Kelly Warren Burak, Morris Sherman

“…Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide and its incidence has rapidly increased in North America in recent years. …”
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Tramadol use and incident dementia in older adults with musculoskeletal pain: a population-based retrospective cohort study by Si Nae Oh, Hye Jun Kim, Jae Yong Shim, Kyuwoong Kim, Seogsong Jeong, Sun Jae Park, Sang Hyun Lee, Joong Won Ha, Sang Min Park

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Perforin-2 is dispensable for host defense against Aspergillus fumigatus and Candida albicans by Mariano A. Aufiero, Li-Yin Hung, De'Broski R. Herbert, Tobias M. Hohl

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Poorly Differentiated Neuroendocrine Tumor of the Rectum Coexistent with Giant Rectal Villous Adenoma Presenting as McKittrick-Wheelock Syndrome by Sammy G. Nakhla, Traci T. Murakami, Srinath Sundararajan

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Research on Lung Nodule Detection Based on Improved Target Detection Network by Ye Li, Qian Wu, Hongwei Sun, Xuewei Wang

“…Lung nodules are an early symptom of lung cancer. The earlier they are found, the more beneficial it is for treatment. …”
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A Presentation of Massive Hemoptysis in a Patient with Churg-Strauss Syndrome by Fadi Hikmat, David B Pearse, Mahendra Damarla

“…Given that Churg-Strauss syndrome is a systemic small-vessel vasculitis, it is not usually considered in patients who present with massive hemoptysis, which is typically caused by bronchiectasis, cancer or, in some cases, aberrant bronchial arteries. …”
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Chikungunya Virus Infection and Acute Elevation of Serum Prostate-Specific Antigen by William Derval Aiken, Joshua J. Anzinger

“…A man with prostate cancer on a regime of active surveillance had a laboratory-confirmed acute Chikungunya virus infection. …”
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A case of pityriasis rubra pilaris secondary to ponatinib by Ariana Nateghi, Florence Lagacé-Thomassin, Julie Desrochers

“…This case underscores the importance of managing dose-dependent skin reactions while maintaining cancer therapy.…”
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Butyrate-engineered yeast activates Nppa and Sgcg genes and reduces radiation-induced heart damage via the gut-heart axis by Jiahao Wu, Kaihua Ji, Guangbo Kang, Manman Zhang, Jigang Wang, Lina Wang, Mengxue Gao, Xiaoxiao Jia, Xinran Lu, Yan Wang, Xinran Gao, Yufei Guo, Zhixin Zhu, Qinghua Wang, Zhenyu Zhao, Qiang Liu, He Huang

“…Radiotherapy is a method of treating cancer through radiation aimed at killing cancer cells or inhibiting their growth. …”
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