Analysis of vaginal microbiota before and after treatment of high-grade squamous intraepithelial lesions of the uterine cervix by Patrícia Mendonça Ventura, Isabel Cristina Chulvis do Val Guimarães, Luis Guillermo Coca Velarde, Susana Cristina Aidé Viviani Fialho, Douglas Guedes Ferreira, Matheus Madureira Fernandes, Rafael Augusto Chaves Machado

“…The persistence of HPV is the main cause for the development of precursor lesions and cervical cancer. …”
Get full text

Biochar filtration of drug-resistant bacteria and active pharmaceutical ingredients to combat antimicrobial resistance by Paul-Enguerrand Fady, Alexandra K. Richardson, Leon P. Barron, A. James Mason, Roberto Volpe, Meredith R. Barr

Get full text

Racial disparities in extended venous thromboembolism prophylaxis after hysterectomy. by Wenbo Wu, Sherry Wu, Sim Berlene Mariano, Richard E Burney, Jonathan P Kuriakose

“…<h4>Background</h4>Venous thromboembolism (VTE) is a significant preventable cause of postoperative morbidity and mortality after major abdominopelvic surgery that calls for extended VTE prophylaxis (eVTEp). …”
Get full text

Familial Lymphoproliferative Malignancies and Tandem Duplication of NF1 Gene by Gustavo Fernandes, Mirela Souto, Frederico Costa, Edite Oliveira, Bernardo Garicochea

“…Neurofibromatosis type 1 is a genetic disorder caused by loss-of-function mutations in a tumor suppressor gene (NF1) which codifies the protein neurofibromin. …”
Get full text

Best practices in the management of thyroid dysfunction induced by immune checkpoint inhibitors by Ichiro Yamauchi, Daisuke Yabe

“…Immune checkpoint inhibitors (ICIs) frequently cause immune-related adverse events (irAEs), with thyroid irAEs being the most common endocrine-related irAEs. …”
Get full text

Acyl-CoA Thioesterase 1 Contributes to Transition of Steatosis to Metabolic-Associated Steatohepatitis by Elisa Pasini, Cristina Baciu, Marc Angeli, Bianca Arendt, Diogo Pellegrina, Jüri Reimand, Keyur Patel, George Tomlinson, Mohammad T. Mazhab-Jafari, Lakshmi P. Kotra, Sandra Fischer, Johane P. Allard, Atul Humar, Mamatha Bhat

Get full text

The Dutch version of the Dignity Therapy Question Protocol for individual Dutch nursing home residents without cognitive impairments (during COVID-19): a pilot study by Herman van Dammen, Kris Vissers, Gert-Jan van der Putten, Yvonne Engels

“…However, the words ‘dignity’ and ‘therapy’ caused confusion. The mean number of words in the legacy document was 1078 words, which appeared shorter than in a community-based hospice setting or patients with metastatic cancer or terminally ill people. …”
Get full text

Host factor PLAC8 is required for pancreas infection by SARS-CoV-2 by Lesly Ibargüen-González, Sandra Heller, Darío López-García, Hanna Dietenberger, Thomas FE Barth, Patricia Gallego, Israel Fernández-Cadenas, Sayoa Alzate-Piñol, Catalina Crespí, Julieth A. Mena-Guerrero, Eugenia Cisneros-Barroso, Alejandro P. Ugalde, Gabriel Bretones, Charlotte Steenblock, Alexander Kleger, Marta L. DeDiego, Carles Barceló

Get full text

Tissue-specific roles of de novo DNA methyltransferases by Dániel Márton Tóth, Flóra Szeri, Mária Ashaber, Muhyiddeen Muazu, Lóránt Székvölgyi, Tamás Arányi

“…Additionally, somatic mutations cause common conditions such as osteoarthritis, osteoporosis, clonal hematopoiesis of indeterminate potential (CHIP), hematologic malignancies, and cancer. …”
Get full text

A prognostic model of 8-T/B cell receptor-related signatures for hepatocellular carcinoma by Xuan Zuo, Hui Li, Shi Xie, Mengfen Shi, Yujuan Guan, Huiyuan Liu, Rong Yan, Anqi Zheng, Xueying Li, Jiabang Liu, Yifan Gan, Haiyan Shi, Keng Chen, Shijie Jia, Guanmei Chen, Min Liao, Zhanhui Wang, Yanyan Han, Baolin Liao

“…Abstract Background Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide. The T cell receptor (TCR) and B cell receptor (BCR) are the receptors on the surface of T or B cell, which are crucial for recognizing tumor antigens. …”
Get full text

Erythematous ulcero-proliferative exophytic lesion in an oral squamous cell carcinoma patient- An unusual case of Trichosporonosis by Umamaheswari Kesavachandran, C Arun Kumar

“…We report a rare case of Trichosporon asahii causing erythematous oral lesion in a patient with squamous cell carcinoma. …”
Get full text

Uveal Melanoma and its Various Presentations – A Series of Case Reports by Sujit Das

“…Ocular melanoma is usually a secondary cancer and very rare. Ocular melanoma typically does not cause early signs or symptoms and hence is difficult to detect. …”
Get full text

Beyond the Definitions of the Phenotypic Complications of Sickle Cell Disease: An Update on Management by Samir K. Ballas, Muge R. Kesen, Morton F. Goldberg, Gerard A. Lutty, Carlton Dampier, Ifeyinwa Osunkwo, Winfred C. Wang, Carolyn Hoppe, Ward Hagar, Deepika S. Darbari, Punam Malik

Get full text

Hepatitis C Infection and Periodontal Disease: Is there a Common Immunological Link? by Dorin Nicolae Gheorghe, Liliana Foia, Vasilica Toma, Amelia Surdu, Elena Herascu, Dora Maria Popescu, Petra Surlin, Cristin Constantin Vere, Ion Rogoveanu

“…HCV infection can determine direct extrahepatic manifestations at the oral and periodontal level including oral lichen planus, Sjögren-like sialadenitis, and oral cancer. The changes caused by the infection in the subjects’ immune system, diet, and lifestyle can facilitate the development of oral conditions such as periodontal disease. …”
Get full text

Clinical Practice Guidelines of Russian Gastroenterological Association, Scientific Society for the Clinical Study of Human Microbiome, Russian Society for the Prevention of Non-Co... by V. T. Ivashkin, T. L. Lapina, I. V. Maev, O. M. Drapkina, R. S. Kozlov, A. A. Sheptulin, A. S. Trukhmanov, S. R. Abdulkhakov, O. P. Alekseeva, S. A. Alekseenko, D. N. Andreev, D. S. Bordin, N. N. Dekhnich, I. L. Klyaritskaya, N. V. Korochanskaya, M. F. Osipenko, E. A. Poluektova, A. S. Sarsenbaeva, V. I. Simanenkov, A. V. Tkachev, A. I. Ulyanin, I. B. Khlynov, V. V. Tsukanov

“…Aim: bring to the attention of practitioners indications for anti-Helicobacter therapy, methods and procedure for diagnostics and eradication therapy of Н. pylori infection.Key points. Chronic gastritis caused by Н. pylori infection, including asymptomatic persons, may be considered as an indication for eradication therapy of Н. pylori as etiological therapy and opportunistic screening for gastric cancer prevention. …”
Get full text

Association of blood cadmium and physical activity with mortality: A prospective cohort study by Yilin Chen, Cien Zhen, Lin Zeng, Hongliang Feng, Jinyu Wang, Qi Yong H. Ai, Sizhi Ai, Jihui Zhang, Yannis Yan Liang, Huachen Xue, Yujing Zhou

“…Achieving recommended PA significantly attenuated the detrimental effects of blood cadmium on all-cause, CVD, and cancer mortality risks.…”
Get full text

Virtual bronchoscopic navigation and guided radial endobronchial ultrasound for peripheral pulmonary lesions: harmonizing modalities to optimize accuracy by Parul Mrigpuri, Sidharth Raj Yadav, Divyendu Sharma, Sonam Spalgais, Vidushi Rathi, Nitin Goel, Balakrishnan Menon, Raj Kumar

“… Peripheral pulmonary lesions (PPLs) present a significant diagnostic challenge due to their location beyond the reach of traditional bronchoscopy. With lung cancer being the leading cause of cancer-related mortality worldwide, accurate and early diagnosis of PPLs is crucial. …”
Get full text

Treatment Patterns and Health Care Costs in Commercially Insured Patients with Follicular Lymphoma by Nathan H. Fowler, Guifang Chen, Stephen Lim, Stephanie Manson, Qiufei Ma, Frank Li

“…**Background:** Few studies have estimated the real-world economic burden such as all-cause and follicular lymphoma-related costs and health care resource utilization (HCRU) in patients with follicular lymphoma (FL). …”
Get full text

Calculated Tumor Volume Is an Independent Predictor of Biochemical Recurrence in Patients Who Underwent Retropubic Radical Prostatectomy by Nobumichi Tanaka, Kiyohide Fujimoto, Akihide Hirayama, Yasushi Nakai, Yoshitomo Chihara, Satoshi Anai, Atsushi Tomioka, Keiji Shimada, Noboru Konishi, Yoshihiko Hirao

“…Among the significant preoperative and postoperative parameters, calculated cancer volume remained an independent predictive parameter in multivariate analysis (𝑃<0.01). …”
Get full text

The effect of consuming bread contaminated with heavy metals on cardiovascular disease and calculating its risk assessment by Kambiz Ahmadi Angali, Majid Farhadi, Abdolkazem Neisi, Bahman Cheraghian, Mehdi Ahmadi, Afshin Takdastan, Abdolah Dargahi

“…The findings indicated that bread intake in the study region is not correlated with non-carcinogenic or carcinogenic risks, since the cancer risk and incremental lifetime cancer risk for both groups were below 1*10^-6. …”
Get full text