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Alternative Splicing Programs in Prostate Cancer
Published 2013-01-01“…Prostate cancer (PCa) remains one of the most frequent causes of death for cancer in the male population. …”
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103
Biophysical Insights into Cancer Transformation and Treatment
Published 2013-01-01“…The metabolic energy transduction pathways are strongly affected in cancers. Mitochondrial dysfunction in cancer cells (Warburg effect) or in fibroblasts associated with cancer cells (reverse Warburg effect) results in decreased or increased power of the generated electromagnetic field, respectively, and shifted and rebuilt frequency spectra. …”
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Global burden of five major types of gastrointestinal cancer
Published 2024-07-01“…Gastrointestinal (GI) cancers cause major global morbidity and mortality, with over 5 million new cases and 3.5 million deaths in 2020. …”
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105
Interplay between Epigenetics and Genetics in Cancer
Published 2013-12-01“…Genomic instability, which occurs through both genetic mechanisms (underlying inheritable phenotypic variations caused by DNA sequence-dependent alterations, such as mutation, deletion, insertion, inversion, translocation, and chromosomal aneuploidy) and epigenomic aberrations (underlying inheritable phenotypic variations caused by DNA sequence-independent alterations caused by a change of chromatin structure, such as DNA methylation and histone modifications), is known to promote tumorigenesis and tumor progression. …”
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106
PROTAC technology for prostate cancer treatment
Published 2025-01-01“…The metastatic spread of PrCa is the primary cause of mortality, causing cancer cell dissemination to distant sites, such as bones, the pelvis, and various visceral organs. …”
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Racial Differences in the Incidence of Colorectal Cancer
Published 2010-01-01“…BACKGROUND: Colon cancer is one of the most common cancers and the second most common cause of cancer mortality in Western societies. …”
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T Cells in Gastric Cancer: Friends or Foes
Published 2012-01-01“…Gastric cancer is the second cause of cancer-related deaths worldwide. …”
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109
Premature Mortality from Colorectal Cancer
Published 2020-12-01“…<strong>Background:</strong> colorectal cancer is the third most common form of cancer and the second most important cause of mortality associated with cancer in America. …”
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Cervical uterine cancer: prevention and treatment
Published 2020-08-01“…It still is the leading cause of morbidity and mortality in women in developing countries. …”
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Tumours and cancers in Graeco-Roman times
Published 2005-06-01“… In Graeco-Roman times all tumours (Greek: onkoi, abnormal swellings) were considered to be of inflammatory origin, the result of unfavourable humoural fluxes, and caused by an extravascular outpouring of fluid into tissue spaces. …”
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Fecal DNA Screening in Colorectal Cancer
Published 2008-01-01“…Colorectal cancer (CRC) is the third most common type of cancer diagnosed in Canada, and is the leading cause of cancer-related deaths in nonsmokers. …”
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Adjuvants for peptide-based cancer vaccines
Published 2016-09-01“…In particular, immune checkpoint blockade therapies with anti-CTLA-4 and anti-PD-1/PD-L1 are causing dramatic tumor shrinkage and prolonged patient survival in a variety of cancers. …”
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Human microbiomes in cancer development and therapy
Published 2023-04-01“…It is largely unknown how microbial agents cause cancer or how cancer progresses. We expect this review may open new perspectives on possible therapeutic approaches of patients with cancer.…”
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Melanosis coli in patients with colon cancer
Published 2016-12-01“…The cause-effect relationship between melanosis coli and colon cancer remains uncertain.…”
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Biomarkers of inflammation and colorectal cancer risk
Published 2025-02-01“…Globally, colorectal malignancy ranks among the most prevalent forms of cancer and stands as the third principal cause of cancer-associated mortality. …”
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Immunotherapy in colorectal cancer: Statuses and strategies
Published 2025-01-01“…Colorectal cancer (CRC) is widely recognized as the third most prevalent malignancy globally and the second leading cause of cancer-related mortality. …”
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118
Recent advances of nanovaccines on cancer theranostics
Published 2025-02-01“…Cancer is a leading cause of death worldwide, with an estimated 20 million new cancer cases and 9.7 million cancer deaths worldwide in 2022. …”
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The Role of PDGFs and PDGFRs in Colorectal Cancer
Published 2017-01-01“…Introduction. Colorectal cancer (CRC) is an important cause of morbidity and mortality worldwide. …”
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Mechanisms of Cancer-Induced Bone Pain
Published 2025-01-01“…Cancer-induced bone pain (CIBP) is a persistent and intense pain that is caused by a combination of inflammatory and neuropathic factors. …”
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