-
721
Persistent oral HPV infections – Are we vaccinating against the right HPV types to prevent HPV-related oropharyngeal cancer?
Published 2024-06-01“…HPV-related oropharyngeal cancers are increasing. These cancers are thought to be preceded by several years of persistent oral HPV infection. …”
Get full text
Article -
722
Single-cell RNA sequencing and immune microenvironment analysis reveal PLOD2-driven malignant transformation in cervical cancer
Published 2025-01-01“…BackgroundCervical cancer is the fourth most common cancer in women globally, and the main cause of the disease has been found to be ongoing HPV infection. …”
Get full text
Article -
723
The Impact of Nutritional Status and Tumor-Infiltrating Lymphocytes (CD4+ and CD8+) on Chemotherapy Response in Colorectal Cancer Patients
Published 2025-01-01“…Nutritional status, levels of CD4+ and CD8+ were significantly associated with chemotherapy responses in CRC patients (p< 0.001).Conclusion: Nutritional status and elevated TIL levels (CD4+/CD8+) positively correlate with better chemotherapy response in CRC patients.Plain Language Summary: Colorectal cancer is the second leading cause of cancer-related deaths worldwide, with 1.9 million new cases reported annually, according to the World Health Organization. …”
Get full text
Article -
724
The interpretation of Use of Adjuvant Bisphosphonates and Other Bone-Modifying Agents in Breast Cancer: ASCO-OH (CCO) Guideline Update
Published 2024-09-01“…Bone-modifying agents (BMAs), including bisphosphonate (BP) and denosumab, can reduce bone-related events caused by breast cancer bone metastasis. “Use of Adjuvant Bisphosphonates and Other Bone-Modifying Agents in Breast Cancer: ASCO-OH (CCO) Guideline Update” was published in Journal of Clinical Oncology in January 2022. …”
Get full text
Article -
725
Impact of late effects after treatment for bladder cancer with radical cystectomy on Quality of life: a case-control study
Published 2025-01-01“…Background and purpose: The gold standard when treating muscle-invasive bladder cancer (MIBC) is radical cystectomy (RC), a procedure that holds the potential to affect the function of several pelvic organs, causing an impact on the patient’s Quality of Life (QoL). …”
Get full text
Article -
726
Evaluation of Antiproliferative Activity of Red Sorghum Bran Anthocyanin on a Human Breast Cancer Cell Line (MCF-7)
Published 2011-01-01“…Breast cancer is a leading cause of death in women worldwide both in the developed and developing countries. …”
Get full text
Article -
727
FBXW7 metabolic reprogramming inhibits the development of colon cancer by down-regulating the activity of arginine/mToR pathways.
Published 2025-01-01“…FBXW7 is a tumor suppressor gene that regulates metabolism and is associated with the onset and progression of colorectal cancer (CRC)), however, the precise mechanism whereby FBXW7 participates in the metabolic reprogramming of CRC remains unclear. …”
Get full text
Article -
728
Evaluation of the Anti-Cancer Efficacy of Cyclooxygenase Inhibition in Combination with Nutrient Starvation on Pancreatic Ductal Adenocarcinoma <em>In Vitro</em>
Published 2024-12-01“…Objective: Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer related deaths. Despite the advancements in cancer management, novel targets to improve treatment outcomes for PDAC are still needed. …”
Get full text
Article -
729
A Urine Metabonomics Study of Rat Bladder Cancer by Combining Gas Chromatography-Mass Spectrometry with Random Forest Algorithm
Published 2020-01-01“…A urine metabolomics study based on gas chromatography-mass spectrometry (GC-MS) and multivariate statistical analysis was applied to distinguish rat bladder cancer. Urine samples with different stages were collected from animal models, i.e., the early stage, medium stage, and advanced stage of the bladder cancer model group and healthy group. …”
Get full text
Article -
730
Fluorescent, Plasmonic, and Radiotherapeutic Properties of the Lu–Dendrimer-AuNP–Folate–Bombesin Nanoprobe Located Inside Cancer Cells
Published 2017-05-01“…The 177 Lu–DenAuNP–folate–bombesin nanoprobe internalized in cancer cells exhibited properties suitable for optical imaging, plasmonic–photothermal therapy, and targeted radiotherapy.…”
Get full text
Article -
731
CRAT downregulation promotes ovarian cancer progression by facilitating mitochondrial metabolism through decreasing the acetylation of PGC-1α
Published 2025-01-01“…Our bioinformatics analysis using public database revealed a significant decrease of CRAT expression in ovarian cancer (OC). However, the functions of CRAT have rarely been investigated in human cancers, especially in OC. …”
Get full text
Article -
732
The Proapoptotic Effect of MB-653 Is Associated with the Modulation of Metastasis and Invasiveness-Related Signalling Pathways in Human Colorectal Cancer Cells
Published 2025-01-01“…Colorectal cancer is one of the most common cancers worldwide and has a high mortality rate. …”
Get full text
Article -
733
Anti-proliferative and photodynamic activities of Senna didymobotrya (Fresen.) leaf alkaloid-rich extracts against breast cancer cells
Published 2025-01-01“…Abstract Background Amongst all neoplastic diseases, breast cancer represents a major cause of death among the female population in developed and developing countries. …”
Get full text
Article -
734
Effects of Tp53 Gene Mutations on the Survival of Non-Small Cell Lung Cancer (NSCLC); A Short Review
Published 2025-01-01“…Chi Zhang,1,2,* Chao Yang,3,* Qingming Shi1,2 1Department of Oncology, Anhui Chest Hospital, Hefei, 230022, People’s Republic of China; 2Anhui Medical University Clinical College of Chest, Hefei, 230022, People’s Republic of China; 3Department of Urology, Anhui Provincial Children’s Hospital, Hefei, 230022, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qingming Shi, Email shqm0324@163.com, shqm0324@hotmail.comAbstract: Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related deaths worldwide. …”
Get full text
Article -
735
Characterization and application of fluorescent hydrogel films with superior mechanical properties in detecting iron(Ⅲ) ions and ferroptosis in oral cancer
Published 2025-01-01“…In view of the promising Fe3+ detection capacity, this hydrogel film can also be applied in oral bacteria surveillance and semi-quantification of ferroptosis in oral cancer.…”
Get full text
Article -
736
Expression of Intratumoral IGF-II Is Regulated by the Gene Imprinting Status in Triple Negative Breast Cancer from Vietnamese Patients
Published 2015-01-01“…African American women suffer higher incidence and mortality of triple negative breast cancer (TNBC) than Caucasian women. TNBC is very aggressive, causing the worst clinical outcome. …”
Get full text
Article -
737
Bufalin targets the SRC-3/c-Myc pathway in chemoresistant cells to regulate metastasis induced by chemoresistance in colorectal cancer
Published 2025-02-01“…Moreover, the clinical drug cinobufacini and its main active monomer bufalin reduced liver metastasis of colorectal cancer caused by chemoresistance in vivo. Conclusion Bufalin can target the SRC-3/c-Myc signaling pathway to affect the prometastatic effect of chemoresistant cells, suggesting that bufalin may be used as a new adjuvant antimetastatic therapy for colorectal cancer.…”
Get full text
Article -
738
Activating Transcription Factor 5 Promotes Tumorigenic Capability in Cervical Cancer Through the Wnt/β-Catenin Signaling Pathway
Published 2025-01-01“…Fengjuan Shi,1,2 Yumei Wei,2 Yingmei Huang,2 Desheng Yao1 1Department of Gynecologic Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, People’s Republic of China; 2Department of Gynecology, the Fifth Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of ChinaCorrespondence: Desheng Yao, Email yaodesheng@gxmu.edu.cnPurpose: Cervical cancer is the fourth leading cause of cancer-related death in women. …”
Get full text
Article -
739
Assessing the rates of false-positive ovarian cancer screenings and surgical interventions associated with screening tools: a systematic review
Published 2024-07-01“…No studies examined the effect these interventions had on patients’ quality of life or directly reported the associated costs of these interventions.Conclusion This review highlights the significant variability in ovarian cancer screening results, which lead to unnecessary and invasive surgical procedures causing complications such as perforation, blood loss and bowel injury.…”
Get full text
Article -
740
Could serum Raftlin and GPER-1levels be new biomarkers for early detection of non-small cell lung cancer?
Published 2025-01-01“…Abstract Background Lung cancer is the leading cause of cancer-related deaths worldwide. …”
Get full text
Article