Selective arm-usage of pre-miR-1307 dysregulates angiogenesis and affects breast cancer aggressiveness by Oyku Ece Sumer, Korbinian Schelzig, Janine Jung, Xiaoya Li, Janina Moros, Luisa Schwarzmüller, Ezgi Sen, Sabine Karolus, Angelika Wörner, Verônica Rodrigues de Melo Costa, Nishanth Belugali Nataraj, Efstathios-Iason Vlachavas, Clarissa Gerhäuser, Karin Müller-Decker, Dominic Helm, Yosef Yarden, Birgitta Elisabeth Michels, Cindy Körner

“…Abstract Background Breast cancer is the leading cause of cancer-related mortality in women. …”
Get full text

Practices regarding human Papillomavirus counseling and vaccination in head and neck cancer: a Canadian physician questionnaire by Scott Anderson, Andre Isaac, Caroline C. Jeffery, Joan L. Robinson, Daniela Migliarese Isaac, Christina Korownyk, Vincent L. Biron, Hadi Seikaly

“…Abstract Background Human papillomavirus (HPV) has recently been implicated as a causative agent in a rapidly growing number of oropharyngeal cancers. Emerging literature supports the hypothesis that HPV vaccination may protect against HPV-related head and neck cancer (HNC) in addition to HPV-related cervical and anogenital disease. …”
Get full text

Applications of Indocyanine Green in Breast Cancer for Sentinel Lymph Node Mapping: Protocol for a Scoping Review by Feryal Kurdi, Yahya Kurdi, Igor Vladimirovich Reshetov

“… Abstract IntroductionBreast cancer is the leading cause of morbidity and mortality worldwide. …”
Get full text

Prognostic factors for head and neck cancer of unknown primary including the impact of human papilloma virus infection by Lars Axelsson, Jan Nyman, Hedda Haugen-Cange, Mogens Bove, Leif Johansson, Shahin De Lara, Anikó Kovács, Eva Hammerlid

“…In the last decade, human papilloma virus (HPV) has been identified as a common cause of and important prognostic factor in oropharyngeal cancer, and there is now growing interest in the importance of HPV for HNCUP. …”
Get full text

Research hotspots and frontiers in the tumor microenvironment of colorectal cancer: a bibliometric study from 2014 to 2024 by Xinran He, Tingyi Xie, Li Shi, Xuyi Kuang, Lei Li, Xingyu Shang, Bo Fu

“…BackgroundColorectal cancer (CRC) is the second leading cause of cancer deaths globally, which poses a heavy burden on our healthcare and economy. …”
Get full text

The optimal neoadjuvant treatment strategy for HR+/HER2 + breast cancer: a network meta-analysis by Shiwei Liu, Miao Yu, Exian Mou, Meihua Wang, Shuanghua Liu, Li Xia, Hui Li, Hao Tang, Yajing Feng, Xin Yu, Kun Mi, Hao Wang

“…Abstract The efficacy of neoadjuvant therapy varies significantly with hormone receptor (HR) status for patients with human epidermal growth factor receptor 2 (HER2) positive breast cancer (BC). Despite extensive research on HER2 + BC, the optimal neoadjuvant strategy for HR+/HER2 + BC remains inconclusive. …”
Get full text

Co-modulation of a circular form of PCDH11Y during neuroendocrine differentiation of prostate cancer by Giovanni Pecoraro, Ilaria Leone, Silvia Nuzzo, Santiago Negueruela, Giovanni Smaldone, Lorena Buono

“…IntroductionProstate cancer (PC) is a leading cause of cancer-related deaths among men, often progressing to castration-resistant prostate cancer (CRPC) after androgen deprivation therapy (ADT). …”
Get full text

Global research landscape and emerging trends of non-coding RNAs in prostate cancer: a bibliometric analysis by Yu-Liang Zhou, Yu-Liang Zhou, Wen-Liang Yao, Wen-Liang Yao, Sheng-Hui Chen, Sheng-Hui Chen, Peng Wang, Peng Wang, Jing-Wen Fu, Jing-Wen Fu, Jia-Qin Zhao, Jia-Qin Zhao, Jia-Yi Zhang, Jia-Yi Zhang

“…BackgroundProstate cancer (PC) is the most frequently diagnosed cancer in men and continues to be a major cause of cancer-related mortality worldwide. …”
Get full text

Adjuvant Therapy after Esophagectomy for Esophageal Cancer: Who Needs It?: Multi-institution Worldwide Observational Study by Siva Raja, MD, PhD, Thomas W. Rice, MD, Min Lu, PhD, Marie E. Semple, MPH, Andrew J. Toth, MS, Eugene H. Blackstone, MD, Sudish C. Murthy, MD, PhD, Usman Ahmad, MD, Michael McNamara, MD, Hemant Ishwaran, PhD, for the Worldwide Esophageal Cancer Collaboration Investigators

“…Random forests for survival and virtual-twin analyses were performed for all-cause mortality. Results:. For adenocarcinoma, adjuvant therapy was beneficial only in pT4NanyM0 cancers (6–8 month survival benefit) and in pTanyN3M0 cancers (4–8 month benefit); a survival decrement was observed in pT1-3N0M0 cancers, with no effect on TanyN1-2M0 cancers. …”
Get full text

Self-reported determinants for subjective financial distress: a qualitative interview study with German cancer patients by Eva Winkler, Katja Mehlis, Bastian Surmann, Wolfgang Greiner, Andrea Züger, Viktoria Mathies, Sophie Pauge, Luise Richter, Thomas Ernst, Natalja Menold

“…To better understand subjective financial distress, the presented study explores self-reported determinants for subjective financial distress in German patients with cancer, aiming to inform a new German-language patient-reported outcome measure for determining the financial effects of a tumour disease.Design Semistructured interviews with n=18 patients with cancer were conducted between May 2021 and December 2021. …”
Get full text

Pathophysiology of tumor progression and possibilities of using polarization biomedical optics methods in the diagnosis of papillary thyroid cancer by Yu.Ye. Rohovyi, O.V. Bilookyi, O.H. Ushenko, V.V. Bilookyi

“…A probable inhibition of the average azimuth of polarization of phase digital microscopic images of native histological sections of thyroid biopsy of patients with papillary cancer and a probable decrease in the asymmetry and excess of multifractal spectra of polarization azimuth maps of digital microscopic images of native histological sections of thyroid biopsy of patients with papillary cancer are caused by papillary proliferation of transformed T thyrocytes as an amorphous component in patients with papillary cancer as a result of activation of tumor progression with intensive processes of growth, invasion, and formation of blood vessels to provide blood supply to the tumor.…”
Get full text

GPR137-RAB8A activation promotes ovarian cancer development via the Hedgehog pathway by Chao Tang, Lin Li, Chongying Zhu, Qiang Xu, Zihao An, Shouying Xu, Chao Lin

“…Abstract Background Ovarian cancer (OC) progression is one of the commonest cause of female cancer death. …”
Get full text

Study on the changes and influencing factors of depression in Chinese women with cancer: an analysis based on CHARLS panel data by Na Wang, Mengran Chang, Shidong Liu, Bing Chen

“…BackgroundThe social problems caused by depressive disorders and psychological behaviors in women are increasingly prominent, with extreme incidents occurring from time to time. …”
Get full text

Ginger-Derived Exosome-Like Nanoparticles Loaded With Indocyanine Green Enhances Phototherapy Efficacy for Breast Cancer by Guo Z, Li G, Shen L, Pan J, Dou D, Gong Y, Shi W, Sun Y, Zhang Y, Ma K, Cui C, Li W, Liu Q, Zhu X

“…Zhaoming Guo,1,2,* Guqing Li,2,* Lanjun Shen,2 Jiawei Pan,2 Danni Dou,2 Yuwei Gong,2 Wanwan Shi,2 Yuhua Sun,2 Yi Zhang,2 Kun Ma,2 Changhao Cui,2 Wenxin Li,3,4 Qiang Liu,5 Xudong Zhu1,4,6 1Department of General Surgery, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang, Liaoning, 110042, People’s Republic of China; 2School of Chemical Engineering, Marine and Life Sciences, Dalian University of Technology, Panjin, Liaoning, 124221, People’s Republic of China; 3The second Department of Hepatopancreatobiliary Surgery, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang, Liaoning, 110042, People’s Republic of China; 4Liaoning Provincial Key Laboratory of Precision Medicine for Malignant Tumors, Shenyang, Liaoning, 110042, People’s Republic of China; 5Faculty of Medicine, Dalian University of Technology, Dalian, Liaoning, 116024, People’s Republic of China; 6Department of Oncology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, 110004, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xudong Zhu, Department of General Surgery, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang, Liaoning, 110042, People’s Republic of China, Tel +86 13354204706, Email xdzhu@cmu.edu.cn; XudongZhu@uky.edu Qiang Liu, Faculty of Medicine, Dalian University of Technology, Dalian, Liaoning, 116024, People’s Republic of China, Email andyliu_1844@dlut.edu.cnPurpose: Phototherapy has remarkable advantages in cancer treatment, owing to its high efficiency and minimal invasiveness. …”
Get full text

Five year mortality in an RCT of a lung cancer biomarker to select people for low dose CT screening. by Francis Michael Sullivan, Frances S Mair, William Anderson, Cindy Chew, Alistair Dorward, John Haughney, Fiona Hogarth, Denise Kendrick, Roberta Littleford, Alex McConnachie, Colin McCowan, Nicola McMeekin, Manish Patel, Petra Rauchhaus, Fergus Daly, Lewis Ritchie, John Robertson, Joseph Sarvesvaran, Herbert Sewell, Thomas Taylor, Shaun Treweek, Kavita Vedhara, Stuart Schembri

“…Outcomes were ascertained from Register of Deaths and Cancer Registry. Cox proportional hazards models were used to estimate the hazard ratio of the rate of deaths from all causes and lung cancer. …”
Get full text

Development and Healing Process of Severe Radiodermatitis in Patients With Head and Neck Cancer Undergoing Radiotherapy: A Scoping Review by Nao Miyamae, Yuko Imakata, Mao Kunimitsu, Makoto Oe

“…Conclusions: Moist desquamations are more likely to occur in severe radiodermatitis in patients with head and neck cancer. Since they can fuse and spread, preventative measures to mitigate spreading are important. …”
Get full text

Cancer treatment comes to age: from one-size-fits-all to next-generation sequencing (NGS) technologies by Sepideh Parvizpour, Hanieh Beyrampour-Basmenj, Jafar Razmara, Farhad Farhadi, Mohd Shahir Shamsir

“…Cancer is one of the leading causes of death worldwide and one of the greatest challenges in extending life expectancy. …”
Get full text

Global esophageal cancer epidemiology in 2022 and predictions for 2050: A comprehensive analysis and projections based on GLOBOCAN data by Ling Qi, Mengfei Sun, Weixin Liu, Xuefeng Zhang, Yongjun Yu, Ziqiang Tian, Zhiyu Ni, Rongshou Zheng, Yong Li, Xiangxiang Pan

“…Among the 185 countries worldwide, esophageal cancer was among the top five causes of cancer incidence in 18 countries and among the top five causes of cancer mortality in 25 countries. …”
Get full text

Evaluation of targeted therapy on the activity of curcumin and doxorubicin anticancer agents in breast cancer: A systematic literature review by Indriani Dwi Kartika, Dewi Salma Kumala, Az-zahra Mutiara, Siagian Dina Ariya, Alifatunnisa Nur Iqlima, Lolita Lolita, Novitasari Putri Rachma, Ittiqo Dzun Haryadi, Ikhsanudin Azis

“…Breast cancer is one type of cancer that causes the most deaths in women. …”
Get full text

Factors influencing lateral margin diagnosis challenges in Barrett’s esophageal cancer: a bicenter retrospective study in Japan by Ippei Tanaka, Shuhei Unno, Kazuki Yamamoto, Yoshitaka Nawata, Kimihiro Igarashi, Tomoki Matsuda, Dai Hirasawa

“…Background/Aims We aimed to clarify the clinicopathological characteristics and causes of Barrett’s esophageal adenocarcinoma (BEA) with unclear demarcation. …”
Get full text