The global, regional burden of pancreatic cancer and its attributable risk factors from 1990 to 2021 by Weidong Yu, Danyi Zhou, Fanhao Meng, Jinjing Wang, Bo Wang, Jianling Qiang, Lijun Shen, Maofeng Wang, Hezhi Fang

“…Abstract Background Pancreatic cancer is the 12th most common type of cancer, and the sixth leading cause of cancer-related mortality, worldwide. …”
Get full text

Anthracycline-induced arrhythmias in breast cancer therapy: A meta-analysis of single-arm trials. by Tao Ran, Jinyao Chen, Qiurui She, Yi Mu, Min Zhang, Min Mao, Zhong Zuo, Juan Li

“…<h4>Introduction</h4>As of 2020, breast cancer has emerged as the predominant cause of cancer incidence globally. …”
Get full text

Proton pump inhibitors enhance chemosensitivity, promote apoptosis, and suppress migration of breast cancer cells by Ihraiz Worood G., Ahram Mamoun, Bardaweel Sanaa K.

“…Breast cancer is the most common cancer and is the leading cause of cancer deaths among women worldwide. …”
Get full text

Trends in age‐specific incidence, mortality, and DALYs of female breast cancer from 1990 to 2021 by Subhadra Priyadarshini, Kunja Bihari Panda

“…Abstract Objectives Breast cancer is a leading cause of morbidity and mortality among women worldwide. …”
Get full text

Chronic Obstructive Pulmonary Disease and Lung Cancer Mortality Attributed to Air Pollution in Türkiye in 2019 by Didem Han Yekdeş, Ali Cem Yekdeş, Ülfiye Çelikkalp, Pelin Sarı Serin, Miraç Çağlayan, Galip Ekuklu

“…Abstract Approximately seven million premature deaths occurred due to several health problems caused by air pollution. In this study, we aimed to calculate the mortality rates of lung cancer and Chronic Obstructive Pulmonary Disease (COPD) attributed to PM2.5 in Türkiye in 2019. …”
Get full text

A Novel Pyroptosis-Based Prognostic Model Correlated with the Parainflammatory Immune Microenvironment of Pancreatic Cancer by Kong-kong Wei, Zhi-xing Du, Jun-ge Deng, Jin-wei Yang, Hao Chen

“…The action of pyroptosis-related genes (PRGs) in pancreatic cancer (PC), however, remains uncertain. Methods. …”
Get full text

Inhibition of anti-tumour reactivity of immune cells in the salivary gland cancer: A proteomic approach by Rajdeep Chakraborty, Charbel Darido, Aidan Tay, Thiri Zaw, Shoba Ranganathan, Fei Liu, Giuseppe Palmisano

“…Therefore, we hypothesised that salivary gland cancer cells produce a higher number of immunosuppressive proteins that cause suppression of the immune system's anti-tumour reactivity. …”
Get full text

Applying YOLOv6 as an ensemble federated learning framework to classify breast cancer pathology images by Chhaya Gupta, Nasib Singh Gill, Preeti Gulia, Noha Alduaiji, J. Shreyas, Piyush Kumar Shukla

“…Abstract The most common carcinoma-related cause of death among women is breast cancer. Early detection is crucial, and the manual screening method may lead to a delayed diagnosis, which would delay treatment and put lives at risk. …”
Get full text

Integrated microRNA and mRNA signatures associated with overall survival in epithelial ovarian cancer. by Joanna Lopacinska-Jørgensen, Douglas V N P Oliveira, Guy Wayne Novotny, Claus K Høgdall, Estrid V Høgdall

“…Ovarian cancer (OC), the eighth-leading cause of cancer-related death among females worldwide, is mainly represented by epithelial OC (EOC) that can be further subdivided into four subtypes: serous (75%), endometrioid (10%), clear cell (10%), and mucinous (3%). …”
Get full text

A Nationwide Exploration of Social Inequalities in Cancer Mortality Amidst the COVID‐19 Pandemic in Belgium by Yasmine Khan, Laura Van den Borre, Delphine De Smedt, Nick Verhaeghe, Brecht Devleesschauwer, Patrick Deboosere, Katrien Vanthomme, Sylvie Gadeyne

“…These changes did not significantly alter established socioeconomic patterns in cancer mortality. Conclusions Reductions in reported cancer deaths in 2020 may reflect COVID‐19 prioritization in cause‐of‐death coding and its role as a competing risk, rather than true declines. …”
Get full text

Artificial intelligence in breast cancer survival prediction: a comprehensive systematic review and meta-analysis by Zohreh Javanmard, Saba Zarean Shahraki, Kosar Safari, Abbas Omidi, Sadaf Raoufi, Mahsa Rajabi, Mohammad Esmaeil Akbari, Mehrad Aria

“…BackgroundBreast cancer (BC), as a leading cause of cancer mortality in women, demands robust prediction models for early diagnosis and personalized treatment. …”
Get full text

Repression of PFKFB3 sensitizes ovarian cancer to PARP inhibitors by impairing homologous recombination repair by Yinan Xiao, Yu Wu, Qilong Wang, Mo Li, Chaolin Deng, Xiaoyang Gu

“…Abstract Background Ovarian cancer (OC), particularly high-grade serous ovarian carcinoma (HGSOC), is the leading cause of mortality from gynecological malignancies worldwide. …”
Get full text

A comparative analysis of global and Chinese trends in the burden of kidney cancer from 1990 to 2021 by Zhongli Qiao, Jun Xiong, Shenyu Zhang, Lin Chen, Jialin Wang, Runze Chen

“…The SII(Slope Index of Inequality) and the CI(Concentration Index) were used to assess the DALYs inequality caused by kidney cancer, and the SDI(Socio-demographic Index) was used as the basis for the ranking. …”
Get full text

Mechanistic insights into HPV-positivity in non-smokers and HPV-negativity in smokers with head and neck cancer by Markus Hoffmann, Markus Hoffmann, Susanne Hille, Susanne Hille, Susanne Hille, Asita Fazel, Martin Laudien, Martin Laudien, Susanne Wiegand, Susanne Wiegand, Martin Müller, Oliver J. Müller, Oliver J. Müller, Oliver J. Müller, Elgar Susanne Quabius, Elgar Susanne Quabius

Get full text

Predicting patient outcomes with gene-expression biomarkers from colorectal cancer organoids and cell lines by Alexandra Razumovskaya, Mariia Silkina, Mariia Silkina, Mariia Silkina, Andrey Poloznikov, Timur Kulagin, Maria Raigorodskaya, Nina Gorban, Anna Kudryavtseva, Maria Fedorova, Boris Alekseev, Alexander Tonevitsky, Alexander Tonevitsky, Alexander Tonevitsky, Sergey Nikulin, Sergey Nikulin, Sergey Nikulin

“…IntroductionColorectal cancer (CRC) is characterized by an extremely high mortality rate, mainly caused by the high metastatic potential of this type of cancer. …”
Get full text

Piloting of a Screen-Triage-Treat Surgical Approach Model for Management of Anal Cancer in Liberia by Christopher W. Reynolds, Whitney Lieb, Andrea Schecter, Michael M Gaisa, Stephen K. McGill, Evans L. Adofo, Ann Marie Beddoe

“…Background: While cancer is a leading cause of death worldwide, significant disparities exist in care access in low- and middle-income countries (LMICs). …”
Get full text

Efficacy and safety of nivolumab plus ipilimumab in gastrointestinal cancers: a systematic review and meta-analysis by Bowen Dai, Jiaping Jiang, Xiaoyu Yu, Haihua Zhan, Zhengchuan Hu

“…Regarding safety, there was no statistically significant difference between the combination regimen and the control group in terms of any grade (OR = 0.72, P = 0.26) or grade 3-4 TRAEs (OR = 1.36, P = 0.14).ConclusionsNivolumab in combination with ipilimumab demonstrated significant efficacy in GI cancers (especially esophageal cancer) without causing more adverse reactions. …”
Get full text

Burden of NASH related liver cancer from 1990 to 2021 at the global, regional, and national levels by Shuang Li, Shuang Li, Shuangjiang Li, Linjing Guan, Mingjuan Li, Jiahui Zhao, Min Wu, Qiuyun Li, Hui Li, Guoqing Ouyang, Guangdong Pan, Guangdong Pan

“…BackgroundThe global burden of non-alcoholic steatohepatitis (NASH)-related liver cancer (NRLC) is increasing, making NASH the fastest-growing cause of liver cancer worldwide. …”
Get full text

Previous treatment with anthracycline does not affect the course of sepsis in cancer patients: Retrospective cohort study by Camille Windsor, Adrien Joseph, Stephanie Pons, Djamel Mokart, Frederic Pène, Achille Kouatchet, Alexandre Demoule, Fabrice Bruneel, Martine Nyunga, Edith Borcoman, Matthieu Legrand, Michael Darmon, Lara Zafrani, Elie Azoulay, Virginie Lemiale

“…Like other chemotherapeutic agents, they may cause endothelial toxicity. The aim of this study was to evaluate the effect of anthracycline treatment on the outcome of cancer patients with sepsis. …”
Get full text

Neuropilin1-dependent paracrine signaling of cancer cells mediated by miRNA exosomal cargo by Claudia Palazzo, Roberta Mastrantonio, Noemi Gioelli, Erika Testa, Francesco Recco, Donatella Lucchetti, Giulia Villari, Alessio D’Alessio, Alessandro Sgambato, Flavio Mignone, Guido Serini, Maria Teresa Viscomi, Luca Tamagnone

“…NRP1 expression in human cancers is associated with prominent angiogenesis and advanced progression stage. …”
Get full text