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In vivo trafficking of cancer-derived exosomes and their role in metastasis
Published 2025-06-01“…Cancer metastasis is one of the leading causes of cancer-related mortality. …”
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182
Natural products as part of triple negative breast cancer
Published 2025-01-01“…Triple negative breast cancer (TNBC) continues to be the breast cancer subtype with the highest recurrence and mortality rates. …”
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183
Small Bowel Intussusception due to Metastasized Sarcomatoid Carcinoma of the Lung: A Rare Cause of Intestinal Obstruction in Adults
Published 2012-01-01“…Sarcomatoid carcinoma, a very rare subtype of lung cancer, rarely metastasizes to small bowel and causes complications. …”
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184
Mortality Burden of Cancer of the Lip, Oral Cavity and Pharynx
Published 2022-12-01“…The universe was made up of all deaths from cancer of the lip, oral cavity and pharynx for the years studied. …”
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CALR ins5-mediated clonal hematopoiesis causes severe hemolytic anemia in a female PGK1 Ser320Asn carrier
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187
The Effect of Anesthesia on the Immune System in Colorectal Cancer Patients
Published 2018-01-01“…Colorectal cancer (CRC) is the key leading cause of high morbidity and mortality worldwide. …”
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188
Hybrid discrete-continuous model of invasive bladder cancer
Published 2013-03-01“…This type of cancer starts in theurothelium and progresses towards surroundingmuscles and tissues, causing metastatic disease.Our mathematical model of invasive BC consists of two coupledsub-models: (i) living cycle of the urothelial cells (normal and mutated) simulatedusing discrete technique of Cellular Automata and (ii) mechanism oftumor invasion described by the system of reaction-diffusionequations. …”
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189
Pre-clinical study of curcumin in the treatment of gastric Cancer
Published 2025-02-01“…Gastric cancer is the fifth most common cancer globally and the third leading cause of cancer-related deaths. …”
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190
Ferritin as an Effective Prognostic Factor and Potential Cancer Biomarker
Published 2025-01-01“…It has emerged as a biomarker not only for iron-related disorders but also for inflammatory diseases and conditions in which inflammation plays a key role, including cancer, neurodegeneration, and infection. Oxidative stress, which can cause cellular damage, is induced by reactive oxygen species generated during the Fenton reaction, activating signaling pathways associated with tumor growth and proliferation. …”
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191
Nanotechnology in cancer: advancements in treatment and detection—a review
Published 2024-12-01“…Cancer, characterized by the rapid growth of abnormal cells capable of invading surrounding tissues and metastasis, is a leading cause of mortality worldwide. …”
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192
Colorectal cancer spectrum: From subtypes and epidemiology to oncotherapies
Published 2025-04-01“…Colorectal cancer (CRC) has an incidence rate of 10 % and is the third most common cause of mortality worldwide, following breast and lung cancer. …”
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Treatment of oligometastatic breast cancer: The role of patient selection
Published 2025-02-01“…Up to 90 % of death from solid tumors are caused by metastases. By 2040, breast cancer (BC) is predicted to increase to over 3 million new cases. …”
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195
Active Roles of Tumor Stroma in Breast Cancer Metastasis
Published 2012-01-01“…Metastasis is the major cause of death for breast cancer patients. Tumors are heterogenous cellular entities composed of cancer cells and cells of the microenvironment in which they reside. …”
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196
Midregion PTHrP and Human Breast Cancer Cells
Published 2010-01-01“…The midregion PTHrP domain (38-94)-amide was found to restrain growth and invasion in vitro of some breast cancer cell lines, causing striking toxicity and accelerating death; the most responsive being MDA-MB231, whose tumorigenesis was also attenuated in vivo. …”
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197
Reproductive Late Effects in Female Survivors of Childhood Cancer
Published 2012-01-01“…Childhood cancer treatments can cause female reproductive late effects. …”
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198
DNA Methylation and Chromatin Remodeling: The Blueprint of Cancer Epigenetics
Published 2016-01-01“…Thus, tweaking the epigenetic machinery may help cause or cure diseases, especially cancer. Therefore, cancer epigenetics, especially at a molecular level, needs to be scrutinised closely, as it could potentially serve as the future pharmaceutical goldmine against neoplastic diseases. …”
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199
MicroRNAs in the DNA Damage/Repair Network and Cancer
Published 2014-01-01“…Cancer is a multistep process characterized by various and different genetic lesions which cause the transformation of normal cells into tumor cells. …”
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200
Diagnostic and Prognostic Significance of Exosomes and Their Components in Patients With Cancers
Published 2025-01-01“…ABSTRACT Background Cancer is the second leading cause of human mortality worldwide. …”
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