Low-dose trimethoprim-sulfamethoxazole for the treatment of Pneumocystis jirovecii pneumonia (LOW-TMP): protocol for a phase III randomised, placebo-controlled, dose-comparison tri... by Andrea Benedetti, Cecilia T Costiniuk, Kosar Khwaja, Andrew Johnson, Barret Rush, Darrell Tan, Ranjani Somayaji, Salman Qureshi, Michaeline McGuinty, Nicole Ezer, Sara Belga, Emily G. McDonald, Zahra N. Sohani, Guillaume Butler-Laporte, Andrew Aw, Alex Carignan, Matthew P. Cheng, Bryan Coburn, Dan Gregson, Alexander Lawandi, Victor Leung, Sylvain Lother, Derek MacFadden, Leighanne Parkes, Valerie Roy, Ilan Schwartz, Miranda So, Emilie Trinh, Todd C. Lee

“…The trial will be undertaken at 16 Canadian hospitals. Data will be analysed as intention to treat. …”
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Everyday Pain in Three- to Five-Year-Old Children in Day Care by Carl L von Baeyer, Shannon Baskerville, Patrick J McGrath

“…Twenty-nine children (58%) were observed to experience one or more painful incidents, producing a total of 51 incidents and yielding a median rate of incidents of 0.31 per child per hour, a rate similar to that reported in another Canadian sample. Seven of nine child response items met criteria for reliability in a subsample of incidents observed simultaneously by two observers. …”
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Cannabis use among youth in Canada: a scoping review protocol by Shelley L Craig, Toula Kourgiantakis, Judith Logan, Eunjung Lee, Charmaine C Williams, Travonne Edwards, Ragave Vicknarajah, Monique Simon-Tucker

“…Introduction Canadian youth (aged 15–24) have the highest rates of cannabis use globally. …”
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Promoting Digital Health Data Literacy: The Datum Project by Daniel Powell, Laiba Asad, Elissa Zavaglia, Manuela Ferrari

“… AbstractWith the increased use of digital health innovations in Canadian health care, educating health care users, professionals, and researchers on the ethical challenges and privacy implications of these tools is essential. …”
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Awareness and Uptake of Family Screening in Patients Diagnosed with Colorectal Cancer at a Young Age by Niamh M. Hogan, Marion Hanley, Aisling M. Hogan, Margaret Sheehan, Oliver J. McAnena, Mark P. Regan, Michael J. Kerin, Myles R. Joyce

“…The mean age was 51 (30–59). 66% had node positive disease. 25% had a family history of colorectal cancer in a FDR. While American and Canadian guidelines identified 100% of these patients as requiring screening, British guidelines advocated screening for only 40%. …”
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Meaning mindset theory: a transdiagnostic approach to mental health promotion and intervention for children by Laura Lynne Armstrong, Emmalyne Watt, Catherine Laura Potter, Brent L. Epperson

“…Future research should explore the efficacy of an MMT in therapeutic settings compared to standard treatments, potentially enhancing mental health intervention strategies for Canadian children and families.…”
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A Review of Sulfate Removal from Water Using Polymeric Membranes by Jamal Al Mehrate, Sadek Shaban, Amr Henni

“…Sulfated waters represent a major challenge on the Canadian prairies, leading to many cattle deaths. While reverse osmosis (RO) membranes effectively remove sulfates, they are costly due to high-pressure requirements. …”
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Parallel systems in healthcare: Addressing Indigenous health equity in Canada by Anika Sehgal, Andrea Kennedy, Katharine McGowan, Lynden (Lindsay) Crowshoe

“…The Canadian public healthcare system faces significant challenges in performance. …”
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Le modèle Universal Instructional Design au service de l’égalité des chances dans les universités canadiennes : apports, enjeux et défis by Ruth Philion, Christine Lebel, Louise M. Bélair

“…Recognizing that both groups have comparable needs, American universities and more recently, Canadian universities, have put into place guidelines driven by the Universal Instructional Design which is decidedly inclusive. …”
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In vitro study on the inhibitory effect of various essential oils against murine coronavirus mouse hepatitis virus A-59 replication by Karelle Contant, Shiv Shankar, Monique Lacroix

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Enhancing Pan evaporation predictions: Accuracy and uncertainty in hybrid machine learning models by Khabat Khosravi, Aitazaz A. Farooque, Amir Naghibi, Salim Heddam, Ahmad Sharafati, Javad Hatamiafkoueieh, Soroush Abolfathi

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Social Learning in Bumblebees (Bombus impatiens): Worker Bumblebees Learn to Manipulate and Forage at Artificial Flowers by Observation and Communication within the Colony by Hamida B. Mirwan, Peter G. Kevan

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Evaluating comparative effectiveness of psychosocial interventions for persons receiving opioid agonist therapy for opioid use disorder: protocol for a systematic review by Brian Hutton, Beverley Shea, Kimberly Corace, David Moher, Danielle B Rice, Becky Skidmore, Kednapa Thavorn, Sheena Taha, Dianna Wolfe, Fatemeh Yazdi, Beth A Sproule, Melanie Willows, Patricia Poulin, Gary Garber, Amy Porath, Leila Esmaeilisaraji

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Open-label use of Anakinra (Kineret) in the treatment of patients with osteoarthritis by Craig Davis Scoville, John Partridge Dickson

“…Efficacy of response was determined if patients showed >30% improvement in the Western Ontario and McMaster Universities Osteoarthritis Index and/or Australian/Canadian Osteoarthritis Hand Index scoring with treatment. …”
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DFF-ResNet: An Insect Pest Recognition Model Based on Residual Networks by Wenjie Liu, Guoqing Wu, Fuji Ren, Xin Kang

“…To prove the validity and adaptivity of our approach, we constructed it with two common residual networks (Pre-ResNet and Wide Residual Network (WRN)) and validated these models on the Canadian Institute For Advanced Research (CIFAR) and Street View House Number (SVHN) benchmark datasets. …”
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Analysis of heating degree day requirments changes under climate change in South Khorasan by hossein Imani pour, abdolreza Kashki, mokhtar Karami

“…The latest available scenarios of the fifth report of the Climate Change Interagency Panel (AR5 2014) include RCP scenarios from the Canadian Climate Change website and, using the SDSM macroeconomic statistics software, the data for the upcoming period (2016-2046) in the study area was thrown off. …”
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Quantifying intratumoral biomarker heterogeneity in tubo-ovarian high-grade serous carcinoma to optimize clinical translation by Aline Talhouk, Derek S. Chiu, Liliane Meunier, Kurosh Rahimi, Cécile Le Page, Monique Bernard, Diane Provencher, David G. Huntsman, Anne Marie Mes Masson, Martin Köbel

“…Abstract Intratumoral heterogeneity (ITH) is spatial, phenotypic, or molecular differences within the same tumor that have important implications for accurate tumor classification and assessment of predictive biomarkers. The Canadian Ovarian Experimental Unified Resource (COEUR) has created a cohort of 437 FFPE tissue specimens from 108 tubo-ovarian high-grade serous carcinoma (HGSC) patients to quantify ITH across the anatomical sites and between primary and recurrence. …”
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The landscape of spiritual health and spirituality in Canada: A scoping review protocol. by Helana Marie Boutros, Merna Mina, Nelly Van Doorn-Harder, Maurita T Harris

“…Two reviewers, HMB and MM, will independently and blindly screen all title/abstracts and full-text studies for eligibility. Any Canadian-situated studies that centrally mention and focus on "spirituality" or "spiritual health" will be included. …”
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Cross-Cultural Validation of the English Chronic Pain Myth Scale in Emergency Nurses by Geraldine Martorella, Anaïs Lacasse, Michelle Kostic, Glenna Schluck

“…These patients often face stigmatization, and the ED is no exception. The French-Canadian Chronic Pain Myth Scale (CPMS) was developed to evaluate common societal misconceptions about CP including among healthcare providers. …”
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Social and structural factors that influence refugee women’s use of mental health care services in Canada: A narrative review by Shreya Mahajan, Samantha B. Meyer

“…The aim of this paper is to identify social and structural factors that influence Canadian refugee women’s use (or lack thereof) of mental health care services. …”