Persistent cross-species transmission systems dominate Shiga toxin-producing Escherichia coli O157:H7 epidemiology in a high incidence region: A genomic epidemiology study by Gillian AM Tarr, Linda Chui, Kim Stanford, Emmanuel W Bumunang, Rahat Zaheer, Vincent Li, Stephen B Freedman, Chad R Laing, Tim A McAllister

Get full text

Quantifying intratumoral biomarker heterogeneity in tubo-ovarian high-grade serous carcinoma to optimize clinical translation by Aline Talhouk, Derek S. Chiu, Liliane Meunier, Kurosh Rahimi, Cécile Le Page, Monique Bernard, Diane Provencher, David G. Huntsman, Anne Marie Mes Masson, Martin Köbel

“…Abstract Intratumoral heterogeneity (ITH) is spatial, phenotypic, or molecular differences within the same tumor that have important implications for accurate tumor classification and assessment of predictive biomarkers. The Canadian Ovarian Experimental Unified Resource (COEUR) has created a cohort of 437 FFPE tissue specimens from 108 tubo-ovarian high-grade serous carcinoma (HGSC) patients to quantify ITH across the anatomical sites and between primary and recurrence. …”
Get full text

Investigating the implementation of a Trial of Labour After Caesarean (TOLAC) delivery bundle with respect to decreasing caesarean delivery rates: a multisite quality improvement i... by Eliane M Shore, Elizabeth Miazga, Cheyanne Reed, Alisha Olsthoorn, Isabella Fan, Eliya Zhao, Jodi Shapiro, Amanda Cipolla, Modupe Tunde-Byass

“…Objectives To study the effect of implementing a Trial of Labour After Caesarean (TOLAC) delivery bundle with respect to decreasing caesarean delivery rates across five hospitals.Design Prospective quality improvement study.Setting Five Canadian hospital sites participated, two academic centres and three community hospitals, with annual delivery rates ranging from 2500 to 7500 per site.Participants All obstetrical patients with a singleton gestation in cephalic presentation and only one previous caesarean delivery were included.Interventions A TOLAC bundle was introduced at each hospital site, consisting of three main interventions: (1) education for healthcare providers, (2) a TOLAC discussion sheet and (3) patient educational tools.Primary and secondary outcome measures The primary outcome was the caesarean delivery rate in eligible patients. …”
Get full text

«Talgenism» in the Digital Age: A Domestic History of cMOOC by M. A. Babaeva, E. B. Golubev

“…Rivin and the technology of modern connectivism implemented in the massive open online courses with cMOOC of Canadian researchers G. Siemens and S. Downs have common key features. …”
Get full text

Benefits of the Global Integration Method (Método de Integração Global - MIG) in functional priorities of parents of Brazilian children and adolescents with autism spectrum disorde... by Amanda Aparecida Alves Cunha Nascimento, Deisiane Oliveira Souto, Thalita Karla Flores Cruz, Arthur Felipe Barroso de Lima, Gabriela Silva Oliveira, Vitor Geraldi Haase

“…Methods A total of 241 children/adolescents with ASD (mean age, 6.92 ± 3.61 years) were recruited from different regions of Brazil. 76% (76%) were male, and 40.7% were classified as having support level 2. The Canadian Occupational Performance Measure was administered to parents/caregivers to identify their priorities for their children and to assess changes in performance and satisfaction with priorities after intervention with MIG. …”
Get full text

Predicting complications of major head and neck oncological surgery: an evaluation of the ACS NSQIP surgical risk calculator by Peter S. Vosler, Mario Orsini, Danny J. Enepekides, Kevin M. Higgins

“…Methods Patient records at a major Canadian tertiary care referral center between July 2015 and March 2017 were reviewed for surgical cases including one of six major head and neck oncologic surgeries: total thyroidectomy, total laryngectomy, hemiglossectomy, partial glossectomy, laryngopharyngectomy, and composite resection. …”
Get full text

Constraining Binary Mergers in Active Galactic Nuclei Disks Using the Nonobservation of Lensed Gravitational Waves by Samson H. W. Leong, Justin Janquart, Aditya Kumar Sharma, Paul Martens, Parameswaran Ajith, Otto A. Hannuksela

Get full text

Decoding the chicken gastrointestinal microbiome by PB. Burrows, F. Godoy-Santos, K. Lawther, A. Richmond, N. Corcionivoschi, SA. Huws

“…Geographical locations, and thus environmental effectors, also impacted upon gastrointestinal tract microbiota, with Canadian and European datasets being dominated by Lactobacillus, whilst UK and Chinese datasets were dominated by Eisenbergiella and Bacteroides respectively. …”
Get full text

New Approach Methodologies (NAMs) to assess killer whale (Orcinus orca) estrogen receptor alpha (ERα) transactivation potencies by DDTs and their risks by Dave Arthur R. Robledo, Takahito Kumagawa, Mari Ochiai, Hisato Iwata

“…Risk assessments indicated that the o,p’-DDT-estrogenic equivalency quantities of DDTs in the blubber of both Irish and Canadian Arctic killer whales exceeded the in vitro REC10 of o,p’-DDT, suggesting a significant risk of kwERα-mediated endocrine disruption in these populations. …”
Get full text

Carbon and nitrogen stocks and distributions associated with different vegetation covers and soil profiles in Abisko, northern Sweden by Hugo M.G. Potier, Xavier Raynaud, Yannick Agnan, Alienor Allain, Maryse Castrec-Rouelle, Veronique Vaury, Luc Abbadie, Marie A. Alexis

Get full text

Rural perinatal nursing in Canada: A hermeneutic literature review by Lela V. Zimmer, Martha L.P. MacLeod, Amanda De Smit, Steinunn Jónatansdóttir

“…Tweetable abstract: Canadian rural perinatal nurses’ practices are largely invisible in research and grey literature. …”
Get full text

From Disruption to Reconstruction: Implementing Peer Support in Homelessness During Times of Crisis for Health and Social Care Services by Mathieu Isabel, Daniel Turgeon, Émilie Lessard, Andreea-Cătălina Panaite, Gwenvaël Ballu, Odile-Anne Desroches, Ghislaine Rouly, Antoine Boivin

“…Conclusion: Peer support initiatives in homelessness can be implemented in the Canadian context during periods of crisis—for example, the COVID-19 pandemic—for health and social care services. …”
Get full text

Deep learning model based prediction of vehicle CO2 emissions with eXplainable AI integration for sustainable environment by Gazi Mohammad Imdadul Alam, Sharia Arfin Tanim, Sumit Kanti Sarker, Yutaka Watanobe, Rashedul Islam, M. F. Mridha, Kamruddin Nur

“…Utilizing a dataset from the Canadian government’s official open data portal, we explored the impact of various vehicle attributes on $$\hbox {CO}_{2}$$ CO 2 emissions. …”
Get full text

Hepatitis B care cascade among people with HIV/HBV coinfection in the North American AIDS Cohort Collaboration on Research and Design, 2012-2016. by Jessica Kim, Craig W Newcomb, Dean Carbonari, Jessie Torgersen, Keri N Althoff, Mari M Kitahata, Marina B Klein, Richard D Moore, K Rajender Reddy, Michael J Silverberg, Angel M Mayor, Michael A Horberg, Edward R Cachay, Joseph K Lim, M John Gill, Kara Chew, Timothy R Sterling, Mark Hull, Eric C Seaberg, Gregory D Kirk, Sally B Coburn, Raynell Lang, Kathleen A McGinnis, Kelly A Gebo, Sonia Napravnik, H Nina Kim, Vincent Lo Re, North American AIDS Cohort Collaboration on Research and Design of IeDEA

“…We conducted a cross-sectional study among people living with HIV and HBV coinfection receiving care between January 1, 2012 and December 31, 2016 within 13 United States and Canadian clinical cohorts contributing data to the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD). …”
Get full text

CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trialsResearch in context by Jan Rekowski, Christina Guo, Olga Solovyeva, Munyaradzi Dimairo, Mahtab Rouhifard, Dhrusti Patel, Emily Alger, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Johann de Bono, Thomas R. Jeffry Evans, Elizabeth Garrett–Mayer, Robert M. Golub, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Israel Maia, Adrian Mander, Lynley V. Marshall, James Matcham, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Lesley Seymour, Yoshiya Tanaka, Moreno Ursino, Christopher J. Weir, Christina Yap

Get full text

Varying circumstances surrounding opioid toxicity deaths across ethno-racial groups in Ontario, Canada: a population-based descriptive cross-sectional study by Tara Gomes, Mina Tadrous, Sophie A Kitchen, Frank Crichlow, Tonya J Campbell, Cynthia Damba, Colin H Johnson, Ashley Smoke

Get full text

Applying ‘cultural humility’ to occupational therapy practice: a scoping review protocol by Hardeep Singh, Michelle L A Nelson, Heather Colquhoun, Kristina Marie Kokorelias, Tram Nguyen, Ruheena Sangrar, Sachindri Wijekoon, Erica Nekolaichuk, Sofia Mirzazada, Holly Assaf

“…This scoping review protocol aims to: (1) describe the extent and nature of the published health literature on cultural humility, including concepts, descriptions and definitions and practice recommendations, (2) map the findings from objective one to OT practice using the Canadian Practice Process Framework (CPPF), and (3) conduct a consultation exercise to confirm the CPPF mapping and generate recommendations for the practice of cultural humility in OT.Methods and analysis We will search Ovid Medline, Ovid Embase, Ovid PsycINFO, Ebsco CINAHL Plus, ProQuest ASSIA, ProQuest Sociological Abstracts, ProQuest ERIC, WHO Global Index Medicus, and Web of Science databases. …”
Get full text

A retrospective cohort study: do patients with graves’ disease need to be euthyroid prior to surgery? by Abrar Al Jassim, Tim Wallace, Sarah Bouhabel, Agnieszka Majdan, Michael Hier, Veronique-Isabelle Forest, Richard Payne

“…Methods A retrospective cohort study was conducted at two Canadian centers, one in Montreal and the other in Nova Scotia. …”
Get full text

Solid Right Ventricular Compression by Intraventricular Septum-Hematoma Induced after Percutaneous Coronary Intervention by Ibrahim El-Battrawy, Ibrahim Akin, Benedikt Münz, David Manuel Leistner, Michael Behnes, Thomas Henzler, Holger Haubenreisser, Theano Papavassiliu, Martin Borggrefe, Ralf Lehmann

“…Despite successful PCI with drug eluting stent implantation into the right coronary artery (RCA) the patient complained about recurrent angina pectoris according to Canadian Cardiovascular Society (CCS) class IV. Cardiac magnetic resonance imaging and transthoracic echocardiography revealed a massive 4.9×9.2 cm sized end-diastolic septum-hematoma, which compromised right ventricular cavity. …”
Get full text

Exploring Magnetic Fields in Molecular Clouds through Denoising Diffusion Probabilistic Models by Duo Xu, Jenna Karcheski, Chi-Yan Law, Ye Zhu, Chia-Jung Hsu, Jonathan C. Tan

Get full text