Prevalence and Characterization of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae Isolated in Canadian Hospitals: Results from CANWARD 2007 by Patricia J Baudry, Melissa McCracken, Philippe Lagacé-Wiens, Michael R Mulvey, George G Zhanel, Daryl J Hoban

“…The spread of ESBLproducing bacteria across Canada is polyclonal and is not due to the clonal spread of a single strain.…”
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B7-H4 Pathway in Islet Transplantation and β-Cell Replacement Therapies by Xiaojie Wang, Jianqiang Hao, Daniel L. Metzger, Ziliang Ao, Mark Meloche, C. Bruce Verchere, Lieping Chen, Dawei Ou, Alice Mui, Garth L. Warnock

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Patient and family engagement in infection prevention in the context of the COVID-19 pandemic: defining a consensus framework using the Q methodology – NOSO-COVID study protocol by Laurence Bernard, Nathalie Camille Clavel, Mélanie Lavoie-Tremblay, Alain Biron, Anaick Briand, Jesseca Paquette, Carol Fancott, Marie-Pascale Pomey, Vincent Dumez

“…The overarching objective of the proposed study is to explore how patients and families can effectively be engaged in infection prevention by developing a consensus framework with key stakeholders.Design and methods The proposed study is based on a cross-sectional exploratory study at one of the largest university hospitals in North America (Montreal, Canada). The targeted population is all healthcare professionals, managers and other non-clinical staff members who work on clinical units, and the in-patients and their families. …”
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Experiences of community-dwelling older adults living with multiple chronic conditions: a qualitative study by Sharon Kaasalainen, Jenny Ploeg, Marta Canesi, Kimberly D Fraser, Carrie McAiney, Maureen Markle-Reid, Sinead Dufour, Lisa Garland Baird, Tracey Chambers

“…Objectives The aim of the study was to understand the experiences of living with multiple chronic conditions (MCC) from the perspective of community-living older adults with MCC.Design A qualitative study using an interpretive description approach.Setting Participants were recruited from southern Ontario, Canada.Participants 21 community-living, older adults (≥65 years) with an average of 7.4 chronic conditions including one of diabetes, dementia or stroke.Methods Data were collected through digitally-recorded, in-depth, semi-structured in-person interviews. …”
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Assessing research methodologies used to evaluate inequalities in end-of-life cancer care research: a scoping review protocol by Sam Harper, Natalie G Coburn, Alyson L Mahar, Laura E Davis, Julie Hallet, Peter Tanuseputro, Geetanjali D Datta, Colleen Webber, Allison Wiens, Lauren Konikoff

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High Frequency Vibration Fatigue Behavior of Ti6Al4V Fabricated by Wire-Fed Electron Beam Additive Manufacturing Technology by P. Wanjara, J. Gholipour, E. Watanabe, K. Watanabe, T. Sugino, P. Patnaik, F. Sikan, M. Brochu

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Effect of Colonoscopy Volume on Quality Indicators by David Pace, Mark Borgaonkar, Muna Lougheed, Curtis Marcoux, Brad Evans, Nikita Hickey, Meghan O’Leary, Darrell Boone, Jerry McGrath

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Entrepreneurship in Medical Education: Evaluation of the Entrepreneurship in Healthcare Seminar Series by Amanda Mac, Hayley McKee, Michael Balas, Aazad Abbas, Aida Ahrari, Pawandeep Sandhu, Dante Morra, Sarah McClennan, Alison Freeland

“…However, few medical programs in Canada provide training for students to pursue innovation and entrepreneurship. …”
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Ancient and contemporary shellfish cultivation practices bolster bivalve communities and diversity‐biomass relationships by Kieran D. Cox, Hailey L. Davies, Ben Millard‐Martin, Morgan Black, Margot Hessing‐Lewis, Nicole F. Smith, Francis Juanes, Sarah E. Dudas

“…Here, we use the co‐occurrence of Indigenous clam gardens, shellfish aquaculture farms, and unmodified beaches along Canada's West Coast to test the hypothesis that two different resource management practices, one engineered over millennia and the other decades, bolster contemporary bivalve communities. …”
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Orally administered live BCG and heat-inactivated Mycobacterium bovis protect bison against experimental bovine tuberculosis by Nirajan Niroula, Priya Ghodasara, Nelson Marreros, Bailey Fuller, Haley Sanderson, Slim Zriba, Stew Walker, Todd K. Shury, Jeffrey M. Chen

“…Due to the introduction of M. bovis-infected bison in the 1920s, BTB is now endemic in wood bison (Bison bison athabascae) population within the Wood Buffalo National Park (WBNP) in northern Canada. This disease poses a grave threat to the long-term survival of this ecologically and culturally important species and has the potential to cause zoonotic TB and spill over to BTB-free livestock and other bison herds that live in the surrounding areas. …”
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Rare Taxa Are Key Links in Regional Antimicrobial Resistance Profiles in Dusts Across Diverse North American Regions by Paul B. L. George, Florent Rossi, Marc Veillette, Amélia Bélanger Cayouette, Samantha Leclerc, Cindy Dumais, Nathalie Turgeon, Caroline Duchaine

“…Results indicated that qepA dominates antimicrobial resistance profiles across Canada. However, after they were removed from the dataset, regional profiles were evident based on gene type and richness. …”
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Health-related Quality of Life and Exercise Capacity in Double Lung Transplant Recipients With Baseline Lung Allograft Dysfunction by Alisha Rullay, BSc, Karina Kaur, BSc, Jennifer Holman, PT, Laura C. van den Bosch, MD, Justin G. Weinkauf, MD, Jayan Nagendran, MD, PhD, Rhea A. Varughese, MD, Alim S. Hirji, MD, Dale C. Lien, MD, Jason C. Weatherald, MD, Kieran M. Halloran, MD

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Understanding the experiences of birthing care during COVID-19: A qualitative systematic review by Danielle Macdonald, Kristen Bigelow-Talbert, Amanda Ross-White, Erna Snelgrove-Clarke, Leah Sookhoo

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Empirical evidence for a process-based model of health-related quality of life using network analysis by Nicolette Stogios, Nicolette Stogios, Troy Francis, Troy Francis, Rachel G. Peiris, Aleksandra Stanimirovic, Aleksandra Stanimirovic, Valeria Rac, Valeria Rac, Robert P. Nolan, Robert P. Nolan

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Spot Versus 24-Hour Urine Osmolality Measurement in Autosomal Dominant Polycystic Kidney Disease: A Diagnostic Test Study by Ayub Akbari, Sriram Sriperumbuduri, Shreepryia Mangalgi, Vijay Joshi, Manish Sood, Amos Buh, Mohan Biyani, Christopher McCudden, Gregory L. Hundemer, Pierre Antoine Brown

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CpG-ODN Induces a Dose-Dependent Enrichment of Immunological Niches in the Spleen and Lungs of Neonatal Chicks That Correlates with the Protective Immunity against Escherichia coli by Thushari Gunawardana, Khawaja Ashfaque Ahmed, Kalhari Goonewardene, Shelly Popowich, Shanika Kurukulasuriya, Ruwani Karunarathana, Lisanework E. Ayalew, Ashish Gupta, Betty Lockerbie, Marianna Foldvari, Suresh K. Tikoo, Philip Willson, Susantha Gomis

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Multi-level analysis of gut microbiome extracellular vesicles-host interaction reveals a connection to gut-brain axis signaling by Walid Mottawea, Basit Yousuf, Salma Sultan, Tamer Ahmed, JuDong Yeo, Nico Hüttmann, Yingxi Li, Nour Elhouda Bouhlel, Hebatoallah Hassan, Xu Zhang, Zoran Minic, Riadh Hammami

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Prevalence of Antimicrobial-Resistant Pathogens in Canadian Hospitals: Results of the Canadian Ward Surveillance Study (CANWARD 2007) by George G Zhanel, James A Karlowsky, Mel DeCorby, Kim A Nichol, Aleksandra Wierzbowski, Patricia J Baudry, Philippe Lagacé-Wiens, Andrew Walkty, Frank Schweizer, Heather Adam, Melissa McCracken, Michael R Mulvey, The Canadian Antimicrobial Resistance Alliance (CARA), Daryl J Hoban

“…MEtHODS: Bacterial isolates were obtained between January 1, 2007, and December 31, 2007, inclusive, from patients in 12 hospitals across Canada as part of the Canadian Ward Surveillance Study (CANWARD 2007). …”
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Birthweight and Preterm Birth in Relation to Indicators of Childhood Asthma by Kitaw Demissie, Pierre Ernst, Lawrence Joseph, Margaret R Becklake

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Assessing the Potential Impact of Vaccination Programs on Invasive Pneumococcal Disease: Data from Population-Based Surveillance by Allison McGeer, Karen Green, Lisa Landry, James Talbot, Ellie Goldenberg, The Toronto Invasive Bacterial Diseases Network

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