Discovery and development of ANV419, an IL-2/anti-IL-2 antibody fusion protein with potent CD8+ T and natural killer cell-stimulating capacity for cancer immunotherapy by Patrizia Murer, Barbara Brannetti, Jean-Michel Rondeau, Laetitia Petersen, Nicole Egli, Simone Popp, Catherine Regnier, Kirsten Richter, Andreas Katopodis, Christoph Huber

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On the Considerations of Using Near Real Time Data for Space Weather Hazard Forecasting by A. W. Smith, C. Forsyth, I. J. Rae, T. M. Garton, C. M. Jackman, M. Bakrania, R. M. Shore, G. S. Richardson, C. D. Beggan, M. J. Heyns, J. P. Eastwood, A. W. P. Thomson, J. M. Johnson

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Molecular dynamics and machine learning unlock possibilities in beauty design—A perspective by Yuzhi Xu, Haowei Ni, Fanyu Zhao, Qinhui Gao, Ziqing Zhao, Chia-Hua Chang, Yanran Huo, Shiyu Hu, Yike Zhang, Radu Grovu, Hermione He, John Z. H. Zhang, Yuanqing Wang

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Highly corrosion-resistant and photocatalytic hybrid coating on AZ31 Mg alloy via plasma electrolytic oxidation with organic-inorganic integration by Talitha Tara Thanaa, Mohammad Aadil, Alireza Askari, Arash Fattah-alhosseini, Mohammad Alkaseem, Mosab Kaseem

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SPIRIT-DEFINE explanation and elaboration: recommendations for enhancing quality and impact of early phase dose-finding clinical trials protocolsResearch in context by Moreno Ursino, Guillermo Villacampa, Jan Rekowski, Munyaradzi Dimairo, Olga Solovyeva, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Thomas R. Jeffry Evans, Elizabeth Garrett-Mayer, Robert M. Golub, Christina Guo, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Adrian Mander, Lynley V. Marshall, James Matcham, Dhrusti Patel, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Mahtab Rouhifard, Lesley Seymour, Yoshiya Tanaka, Christopher J. Weir, Johann de Bono, Christina Yap

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CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trialsResearch in context by Jan Rekowski, Christina Guo, Olga Solovyeva, Munyaradzi Dimairo, Mahtab Rouhifard, Dhrusti Patel, Emily Alger, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Johann de Bono, Thomas R. Jeffry Evans, Elizabeth Garrett–Mayer, Robert M. Golub, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Israel Maia, Adrian Mander, Lynley V. Marshall, James Matcham, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Lesley Seymour, Yoshiya Tanaka, Moreno Ursino, Christopher J. Weir, Christina Yap

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Development and predictors of bipolar disorder in children and adolescents with depressive disorders: a systematic review, meta-analysis, and meta-regression by Gonzalo Salazar de Pablo, Violeta Perez-Rodriguez, Javier de Otazu Olivares, Javier Camacho-Rubio, Aditya Sharma, Ana Catalán, Josefien Breedvelt, Claudia Aymerich, Mihai Pop, Carmen Moreno, Ian Kelleher, Jane Anderson, Paolo Fusar-Poli, Christoph U Correll, Allan H. Young

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Atacama Large Aperture Submillimeter Telescope (AtLAST) science: Our Galaxy [version 2; peer review: 2 approved] by Pamela Klaassen, Maria Beltrán, Alessio Traficante, Mark Booth, Kate Pattle, Jonathan Marshall, Joshua Lovell, Brandt Gaches, Alvaro Hacar, Nicolas Peretto, Caroline Bot, Doris Arzoumanian, Thomas Stanke, Gaspard Duchêne, Ana Duarte Cabral, Antonio Hales, David Eden, Patricia Luppe, Jens Kauffmann, Elena Redaelli, Sebastian Marino, Álvaro Sánchez-Monge, Andrew Rigby, Dmitry Semenov, Eugenio Schisano, Mark Thompson, Silvia Spezzano, Claudia Cicone, Friedrich Wyrowski, Martin Cordiner, Tony Mroczkowski, Doug Johnstone, Luca Di Mascolo, Minju Lee, Eelco van Kampen, Thomas Maccarone, Daizhong Liu, Matthew Smith, Amélie Saintonge, Sven Wedemeyer, Alexander Thelen

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Embracing Generative Artificial Intelligence in Clinical Research and Beyond by Henry P. Foote, MD, Chuan Hong, PhD, Mohd Anwar, PhD, Maria Borentain, MD, Kevin Bugin, PhD, Nancy Dreyer, PhD, MPH, Josh Fessel, MD, PhD, Nitender Goyal, MD, Morgan Hanger, MPP, Adrian F. Hernandez, MD, Christoph P. Hornik, MD, PhD, MPH, Jennifer G. Jackman, PhD, MBA, Alistair C. Lindsay, MD, MPH, DPhil, Michael E. Matheny, MD, Kerem Ozer, MD, Jan Seidel, PhD, Norman Stockbridge, MD, PhD, Peter J. Embi, MD, Christopher J. Lindsell, PhD

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Establishing a physiologically based pharmacokinetic framework for aldehyde oxidase and dual aldehyde oxidase‐CYP substrates by Nihan Izat, Jayaprakasam Bolleddula, Pasquale Carione, Leticia Huertas Valentin, Robert S. Jones, Priyanka Kulkarni, Darren Moss, Vincent C. Peterkin, Dan‐Dan Tian, Andrea Treyer, Karthik Venkatakrishnan, Michael A. Zientek, Jill Barber, J. Brian Houston, Aleksandra Galetin, Daniel Scotcher

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Internet-based cognitive–behavioural therapy for insomnia (ICBT-i): a meta-analysis of randomised controlled trials by Jia Chen, Juan Liu, Yuan-yuan Ye, Ni-ka Chen, Ling Lin, Ya-zhen Liu, Ying Lang, Xun-jun Li, Xin-ju Yang, Xiao-jiang Jiang

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Looking at Infrared Background Radiation Anisotropies with Spitzer: Large-scale Anisotropies and Their Implications by A. Kashlinsky, Richard G. Arendt, M. L. N. Ashby, J. Kruk, N. Odegard

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A Pilot Genome-Wide Association Study in Postmenopausal Mexican-Mestizo Women Implicates the RMND1/CCDC170 Locus Is Associated with Bone Mineral Density by Marisela Villalobos-Comparán, Rogelio F. Jiménez-Ortega, Karol Estrada, Alma Y. Parra-Torres, Anahí González-Mercado, Nelly Patiño, Manuel Castillejos-López, Manuel Quiterio, Juan Carlos Fernandez-López, Bertha Ibarra, Sandra Romero-Hidalgo, Jorge Salmerón, Rafael Velázquez-Cruz

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Effects of diesel exhaust inhalation on cognitive performance in human volunteers: A randomized controlled crossover study by Jason Curran, A.J. Hirsch Allen, Christopher F. Rider, Robin Shutt, Chris Carlsten

“…Volunteers completed five computerised neuropsychological tests of the Cambridge Neuropsychological Test Automated Battery (CANTAB) prior to (2-hr before) and at three timepoints following each exposure condition (0-hr, 3-h post-, and 24-h post-exposure). …”
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Emotion dysregulation and impulsivity as overlapping symptoms in adult Attention-Deficit/Hyperactivity Disorder and Borderline Personality Disorder: severity profiles and associati... by Eszter Kenézlői, Lívia Balogh, Szilvia Somogyi, Evelyn E. Lévay, Zsuzsa Halmai, Zsófia Nemoda, Zsolt S. Unoka, János M. Réthelyi

“…Behavioral impulsivity and delay aversion were assessed using selected tests of the Cambridge Neuropsychological Test Automated Battery, and a computerized decision-making paradigm based on the Rogers decision-making task, respectively. …”
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The Response Regulator OmpR Negatively Controls the Expression of Genes Implicated in Tilimycin and Tilivalline Cytotoxin Production in <i>Klebsiella oxytoca</i> by Ramón G. Varela-Nájera, Miguel A. De la Cruz, Jorge Soria-Bustos, Carmen González-Horta, Ma Carmen E. Delgado-Gardea, Jorge A. Yáñez-Santos, María L. Cedillo, Hidetada Hirakawa, James G. Fox, Blanca Sánchez-Ramírez, Miguel A. Ares

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Changes in glycosphingolipid levels in plasma and cerebrospinal fluid of individuals with Lysosomal Free Sialic Acid Storage Disorder by Marya S. Sabir, Lynne Wolfe, David R. Adams, Carla Ciccone, Forbes D. Porter, William A. Gahl, Marjan Huizing, Frances M. Platt, May Christine V. Malicdan

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Full-length and N-terminally truncated recombinant interleukin-38 variants are similarly inefficient in antagonizing interleukin-36 and interleukin-1 receptors by Alejandro Diaz-Barreiro, Dominique Talabot-Ayer, Arnaud Huard, Gea Cereghetti, Jenna Tonacini, Mike Maillasson, Antonio Francés-Monerris, Erwan Mortier, Gaby Palmer

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Long-Term Safety and Effectiveness of Dimethyl Fumarate in Patients with Multiple Sclerosis Treated in Routine Medical Practice: Final Analysis of the ESTEEM Study by Krupa Shah Pandey, Kathryn Giles, Konstantin Balashov, Richard Macdonell, Jörg Windsheimer, Mikel Martinez, Ivan Božin, Stephanie Raynaud, Matthew Scaramozza, Oksana Mokliatchouk, Zhaonan Sun, Nicholas Belviso, Yayoi Sato, Xiaochen Lin, Annette Okai

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Esophageal oxyhemoglobin saturation as a resuscitative metric in hemorrhagic shock by Julia Garcia Mancebo, Kristen Sack, Padraic Romfh, Yifeng Peng, John Kheir

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