The neurohormone tyramine stimulates the secretion of an insulin-like peptide from the Caenorhabditis elegans intestine to modulate the systemic stress response. by Tania Veuthey, Jeremy T Florman, Sebastián Giunti, Stefano Romussi, María José De Rosa, Mark J Alkema, Diego Rayes

“…The DAF-2/insulin/insulin-like growth factor signaling (IIS) pathway plays an evolutionarily conserved role in regulating reproductive development, life span, and stress resistance. In Caenorhabditis elegans, DAF-2/IIS signaling is modulated by an extensive array of insulin-like peptides (ILPs) with diverse spatial and temporal expression patterns. …”
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Toxic Assessment of Heavily Traffic-related Fine Particulate Matter Using an in-vivo Wild-type Caenorhabditis elegans Model by Meng-Ching Chung, Kuo-Lin Huang, Japheth L. Avelino, Lemmuel L. Tayo, Chih-Chung Lin, Ming-Hsien Tsai, Sheng-Lun Lin, Wan Nurdiyana Wan Mansor, Ching-Kai Su, Sen-Ting Huang

“…In the present study, the toxicity of traffic-related-air-pollutant (TRAP) PM2.5 was evaluated in the animal model Caenorhabditis elegans (C. elegans) using different toxicological endpoints such as lethality, survivability (lifespan), behavioral (head thrashing and body bending), and reproduction (brood size). …”
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Composition analysis of acid hydrolysates from Cucurbita moschata Duch. polysaccharides and their effect on oxidative stress resistance of Caenorhabditis elegans by Wen Jiang, Yakun Zhang, Jiangying Zeng, Jing Yao, Aoxue Lu, Zhiyu Fang, Ge Wang, Weimin Wang, Yongjun Zhang

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A versatile site-directed gene trap strategy to manipulate gene activity and control gene expression in Caenorhabditis elegans. by Haania Khan, Xinyu Huang, Vishnu Raj, Han Wang

“…While several genetic tools for modifying genes or controlling expression separately are available for Caenorhabditis elegans, there are no genetic approaches to generate mutations that simultaneously disrupt gene function and provide genetic access to the cells expressing the disrupted gene. …”
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Diisooctyl phthalate (DIOP) exposure leads to cell apoptosis to HUVEC cells and toxicity to Caenorhabditis elegans through increasing the oxidative stress by Siyuan Luo, Junnan Li, Yuqing Zhou, Zihang Zhai, Qiang Li, Zhenglin Huang, Wencan He, Kejun Zhong, Bo Kong, Zanxian Xia, Hang Fai Kwok, Lipeng Zhu

“…Our current research endeavored to provide a comprehensive evaluation of DIOP's toxicological profile using both cellular and Caenorhabditis elegans models as our in vitro and in vivo study subjects. …”
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Traffic-related-air-pollutant PM2.5 Caused Toxicity on Caenorhabditis elegans with Cotreatment of High-dose Glucose and Tempeh by Jian-He Lu, Ming-Hsien Tsai, Sen-Ting Huang, Jia-De Lee, Ta-Chih Hsiao, Wan Nurdiyana Wan Mansor, How-Ran Chao

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Syzygium malaccense leaf extract-mediated silver nanoparticles: synthesis, characterization, and biomedical evaluation in Caenorhabditis elegans and lung cancer cell line by Santosh Mallikarjun Bhavi, Bothe Thokchom, Sapam Riches Singh, Sukesh Kumar Bajire, Rajesh P. Shastry, B. S. Srinath, Shivanand S. Bhat, Kotresha Dupadahalli, Chandramohan Govindasamy, Swati Ravi Chalekar, B. P. Harini, Ramesh Babu Yarajarla

“…Additionally, SM-AgNPs increased Caenorhabditis elegans survival and reduced paralysis under pathogenic bacterial exposure. …”
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Structure, Immune and Anti-aging Activities of Capsular Polysaccharide Produced by Lactobacillus plantarum W1 by Yongjiao GAO, Kun WANG, Jing ZHAO, Feng ZUO

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Toxic Effects of Hydroxyl- and Amine-functionalized Silica Nanoparticles (SiO2 and NH2-SiO2 NPs) on Caenorhabditis elegans by Danielle E. Que, Wen-Che Hou, Micah Belle Marie Yap Ang, Chih-Chung Lin

Subjects: “…Caenorhabditis elegans…”
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Alkaloids extracted from Dendrobium officinale grown in diverse environments exhibited robust antioxidative and antiaging activity by Yichen Liu, Arome Solomon Odiba, Qi Yu, Jin Xie, Nkwachukwu Oziamara Okoro, Guiyan Liao, Xinchen Zhu, Bin He, Cheng Jin, Wenxia Fang, Bin Wang

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Effects of starter cultures on the metabolite profile, antioxidant activities, and anti-aging properties of tapuy lees by Edward Kevin B. Bragais, Paul Mark B. Medina

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Synergistic activity of Pitstop-2 and 1,6-hexanediol in aggressive human lung cancer cells by Sílvio Terra Stefanello, Caren Rigon Mizdal, Aline Franzen da Silva, Luca Matteo Todesca, Félix Alexandre Antunes Soares, Victor Shahin

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Phenotypic stasis with genetic divergence by Mallard, François, Noble, Luke, Guzella, Thiago, Afonso, Bruno, Baer, Charles F., Teotónio, Henrique

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Sensory experience controls dendritic structure and behavior by distinct pathways involving degenerins by Sharon Inberg, Yael Iosilevskii, Alba Calatayud-Sanchez, Hagar Setty, Meital Oren-Suissa, Michael Krieg, Benjamin Podbilewicz

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<i>Weizmannia coagulans</i> BC99 Attenuates Oxidative Stress Induced by Acute Alcoholic Liver Injury via Nrf2/SKN-1 Pathway and Liver Metabolism Regulation by Ying Wu, Cheng Li, Yinyin Gao, Jie Zhang, Yao Dong, Lina Zhao, Yuwan Li, Shaobin Gu

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Extraction of Antioxidant Peptides and Activity Evaluation of Frog (Rana nigromaculata) Skin by Ultra-high Pressure Assisted Enzyme Hydrolysis by Xicai ZHANG, Rong LI, Yechuan HUANG

“…The antioxidant properties of frog (Rana nigromaculata) skin small molecule peptides were evaluated in Caenorhabditis elegans model as well as in vitro. Taking the yield of highly active small molecule peptides as the index, the response surface method was utilized to optimize the four parameters containing enzyme addition, ultra-high pressure, the action time, and liquid-to-material ratio to determine the best extraction process for small molecule peptides. …”
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Design of the Multi-Bioactive Graphene-Oxide/Gelatin/Alginate Scaffolds as Dual ECM-Mimetic and Specific Wound Healing Phase-Target Therapeutic Concept for Advanced Wound Healing by Marko Demenj, Martina Žabčić, Marija Vukomanović, Tatjana Ilić-Tomić, Dušan Milivojević, Simonida Tomić, Dubravka Živanović, Marija M. Babić Radić

“…No mortality was detected among the <i>Caenorhabditis elegans</i> throughout the incubation period, indicating that the scaffolds are not toxic. …”
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Functions of Fasciculation and Elongation Protein Zeta-1 (FEZ1) in the Brain by Andrés D. Maturana, Toshitsugu Fujita, Shun'ichi Kuroda

“…Fasciculation and elongation protein zeta-1 (FEZ1) is a mammalian ortholog of the Caenorhabditis elegans UNC-76 protein that possesses four coiled-coil domains and a nuclear localization signal. …”
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MicroRNAs in Development by Danielle Maatouk, Brian D. Harfe

“…The functions of the first two miRNAs, lin-4 and let-7, were relatively easy to identify since they were found in forward genetic screens in Caenorhabditis elegans[1,2,3]. However, uncovering the functions of the growing list of miRNAs presents a challenge to developmental biologists. …”
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DOSAGE COMPENSATION: REGULATION OF SEX CHROMOSOME GENE EXPRESSION by E. V. Dementyeva

“…Study of this process in the sex chromosomes of Drosophila melanogaster, Caenorhabditis elegans, and mammals has shown that, despite the common reason of dosage compensation origin, entirely different ways were elaborated to regulate X-linked gene expression level. …”
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