Dual inhibition of BET and EP300 has antitumor activity in undifferentiated pleomorphic sarcomas and synergizes with ferroptosis induction by Stéphanie Verbeke, Aurélien Bourdon, Mathilde Lafon, Vanessa Chaire, Bertolo Frederic, Amina Naït Eldjoudi, Marie-Alix Derieppe, Francis Giles, Antoine Italiano

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Leishmania mexicana pathogenicity requires flagellar assembly but not motility by Tom Beneke, Rachel Neish, Carolina M. C. Catta-Preta, James Smith, Jessica Valli, Ciaran J. McCoy, Andreia Albuquerque-Wendt, Jeremy C. Mottram, Eva Gluenz

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CRISPRware: a software package for contextual gRNA library design by Eric Malekos, Christy Montano, Susan Carpenter

Subjects: “…CRISPR screen…”
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Combinatorial CRISPR screen reveals FYN and KDM4 as targets for synergistic drug combination for treating triple negative breast cancer by Tackhoon Kim, Byung-Sun Park, Soobeen Heo, Heeju Jeon, Jaeyeal Kim, Donghwa Kim, Sang Kook Lee, So-Youn Jung, Sun-Young Kong, Timothy Lu

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Genome-wide CRISPR-based screen identifies E2F transcription factor 1 as a regulator and therapeutic target of aristolochic acid-induced nephrotoxicity by Ziqi Liu, Huan Gao, Guoliang Li, Yongjiang Yu, Mengxing Cui, Honghao Peng, Xinchao Guan, Xue Zhang, Zhihan Zhang, Xiaoyu Shen, Shen Chen, Daochuan Li, Liping Chen, Yongmei Xiao, Wen Chen, Lili Liu, Qing Wang

Subjects: “…Genome-wide CRISPR screen…”
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Kinome-wide CRISPR-Cas9 screens revealed EXOSC10 as a positive regulator of TGF-β signaling by Dingding Wang, Xinhao Zhang, Jianxun Guo, Weijia Liu, Yanchi Zhou, Renxian Wang

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The Continuous Improvement of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)–CRISPR-Associated Protein System Has Led to Its Highly Efficient Application in... by Wanqing Tan, Zhiyuan Wang, Liezhao Liu

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Identification of Mycobacterium tuberculosis intracellular survival-related virulence factors via CRISPR-based eukaryotic-like secretory protein mutant library screen by Weiyi Liu, Yingchao Wang, Jiayuan Zhao, Xinyue Zhang, Zihui Li, Hongyan Jia, Chuanzhi Zhu, Lanyue Zhang, Liping Pan, Zongde Zhang

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Genome-wide CRISPR screen for human factors involved in alternative polyadenylation based on differential localization of CD47 by Chayanin Wuttinontananchai, Junichi Yamamoto, Satoshi Sakamoto, Yuki Yamaguchi

Subjects: “…Genome-wide CRISPR screen…”
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Unraveling the future of genomics: CRISPR, single-cell omics, and the applications in cancer and immunology by A. Vipin Menon, A. Vipin Menon, Bicna Song, Bicna Song, Lumen Chao, Lumen Chao, Diksha Sriram, Pamela Chansky, Pamela Chansky, Ishnoor Bakshi, Jane Ulianova, Wei Li, Wei Li

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A combination of four Toxoplasma gondii nuclear-targeted effectors protects against interferon gamma-driven human host cell death by Brittany Henry, Aubrey J. Phillips, L. David Sibley, Alex Rosenberg

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Rapid and Robust Generation of Homozygous Fluorescent Reporter Knock-In Cell Pools by CRISPR-Cas9 by Jicheng Yang, Fusheng Guo, Hui San Chin, Gao Bin Chen, Ziyan Zhang, Lewis Williams, Andrew J. Kueh, Pierce K. H. Chow, Marco J. Herold, Nai Yang Fu

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A method for benchmarking genetic screens reveals a predominant mitochondrial bias by Mahfuzur Rahman, Maximilian Billmann, Michael Costanzo, Michael Aregger, Amy H Y Tong, Katherine Chan, Henry N Ward, Kevin R Brown, Brenda J Andrews, Charles Boone, Jason Moffat, Chad L Myers

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Rapid and robust validation of pooled CRISPR knockout screens using CelFi by Allister J. Loughran, Shilpa Narina, Jonathon Klein, Jamaica F. Siwak, Jon P. Connelly, Shondra M. Pruett-Miller

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Advances in single-cell analysis, spatial profiling, and gene editing in cancer immunogenomics by Ruidong Xue, Jinghui Cheng, Ning Zhang

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The genetic interaction map of the human solute carrier superfamily by Gernot Wolf, Philipp Leippe, Svenja Onstein, Ulrich Goldmann, Fabian Frommelt, Shao Thing Teoh, Enrico Girardi, Tabea Wiedmer, Giulio Superti-Furga

Subjects: “…CRISPR Screens…”
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HIV-1 latency: From acquaintance to confidant by Chenbo Yang, Ling Tong, Jing Xue

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Large-scale CRISPRi screens link metabolic stress to glioblastoma chemoresistance by Xing Li, Wansong Zhang, Yitong Fang, Tianhu Sun, Jian Chen, Ruilin Tian

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Identification of TUBB3 as an immunotherapy target in lung cancer by genome wide in vivo CRISPR screening by Dan Zhao, Ravindra Deshpande, Kerui Wu, Abhishek Tyagi, Sambad Sharma, Shih-Ying Wu, Fei Xing, Stacey O'Neill, Jimmy Ruiz, Feng Lyu, Kounosuke Watabe

Subjects: “…In vivo CRISPR screening…”
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ChromActivity: integrative epigenomic and functional characterization assay based annotation of regulatory activity across diverse human cell types by Tevfik Umut Dincer, Jason Ernst

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