Showing 1 - 15 results of 15 for search '"CPT: Pharmacometrics & Systems Pharmacology"', query time: 0.04s Refine Results
  1. 1
    Establishing a physiologically based pharmacokinetic framework for aldehyde oxidase and dual aldehyde oxidase‐CYP substrates

    Establishing a physiologically based pharmacokinetic framework for aldehyde oxidase and dual aldehyde oxidase‐CYP substrates by Nihan Izat, Jayaprakasam Bolleddula, Pasquale Carione, Leticia Huertas Valentin, Robert S. Jones, Priyanka Kulkarni, Darren Moss, Vincent C. Peterkin, Dan‐Dan Tian, Andrea Treyer, Karthik Venkatakrishnan, Michael A. Zientek, Jill Barber, J. Brian Houston, Aleksandra Galetin, Daniel Scotcher

    Published 2025-01-01
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  2. 2
    The population pharmacokinetics of dolutegravir co‐administered with rifampicin in Thai people living with HIV: Assessment of alternative dosing regimens

    The population pharmacokinetics of dolutegravir co‐administered with rifampicin in Thai people living with HIV: Assessment of alternative dosing regimens by Baralee Punyawudho, Anan Chanruang, Thornthun Ueaphongsukkit, Sivaporn Gatechompol, Sasiwimol Ubolyam, Yong Soon Cho, Jae Gook Shin, Anchalee Avihingsanon

    Published 2025-01-01
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  3. 3
    To be or not to be, when synthetic data meet clinical pharmacology: A focused study on pharmacogenetics

    To be or not to be, when synthetic data meet clinical pharmacology: A focused study on pharmacogenetics by Jean‐Baptiste Woillard, Clément Benoist, Alexandre Destere, Marc Labriffe, Giulia Marchello, Julie Josse, Pierre Marquet

    Published 2025-01-01
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  4. 4
    A model‐based approach using GSK3772847, an anti‐interleukin‐33 receptor monoclonal antibody, as a showcase to predict SC administration PK and free target dynamics based on PK and total target measurements after IV administration

    A model‐based approach using GSK3772847, an anti‐interleukin‐33 receptor monoclonal antibody, as a showcase to predict SC administration PK and free target dynamics based on PK and... by Jan Berkhout, Dave Fairman, Martijn vanNoort, Tamara J. vanSteeg

    Published 2025-01-01
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  5. 5
    Immunostimulatory/Immunodynamic model of mRNA‐1273 to guide pediatric vaccine dose selection

    Immunostimulatory/Immunodynamic model of mRNA‐1273 to guide pediatric vaccine dose selection by Vijay Ivaturi, Husain Attarwala, Weiping Deng, Baoyu Ding, Sabine Schnyder Ghamloush, Bethany Girard, Javid Iqbal, Saugandhika Minnikanti, Honghong Zhou, Jacqueline Miller, Rituparna Das

    Published 2025-01-01
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  6. 6
    Within‐chain parallelization—Giving Stan Jet Fuel for population modeling in pharmacometrics

    Within‐chain parallelization—Giving Stan Jet Fuel for population modeling in pharmacometrics by Casey Davis, Pavan Vaddady

    Published 2025-01-01
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  7. 7
    Low‐dimensional neural ordinary differential equations accounting for inter‐individual variability implemented in Monolix and NONMEM

    Low‐dimensional neural ordinary differential equations accounting for inter‐individual variability implemented in Monolix and NONMEM by Dominic Stefan Bräm, Bernhard Steiert, Marc Pfister, Britta Steffens, Gilbert Koch

    Published 2025-01-01
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  8. 8
    Is the GFR‐based scaling approach adequate for predicting pediatric renal clearance of drugs with passive tubular reabsorption? Insights from PBPK modeling

    Is the GFR‐based scaling approach adequate for predicting pediatric renal clearance of drugs with passive tubular reabsorption? Insights from PBPK modeling by Sanwang Li, Xuexin Ye, Qiushi Wang, Zeneng Cheng, Feiyan Liu, Feifan Xie

    Published 2025-01-01
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  9. 9
    Mathematical model of the relationship between pH holding time and erosive esophagitis healing rates

    Mathematical model of the relationship between pH holding time and erosive esophagitis healing rates by Colin W. Howden, Carmelo Scarpignato, Eckhard Leifke, Darcy J. Mulford, Gezim Lahu, Axel Facius, Yuhong Yuan, Richard Hunt

    Published 2025-01-01
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  10. 10
    Physiology‐based pharmacokinetic model with relative transcriptomics to evaluate tissue distribution and receptor occupancy of anifrolumab

    Physiology‐based pharmacokinetic model with relative transcriptomics to evaluate tissue distribution and receptor occupancy of anifrolumab by Pradeep Sharma, David W. Boulton, Lynn N. Bertagnolli, Weifeng Tang

    Published 2025-01-01
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  11. 11
    Population pharmacokinetics and pharmacodynamics of edoxaban in pediatric patients

    Population pharmacokinetics and pharmacodynamics of edoxaban in pediatric patients by Peng Zou, Akhilesh Atluri, Peter Chang, Michael Goedecke, Tarek A. Leil

    Published 2025-01-01
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  12. 12
    Population pharmacokinetic modeling of zavegepant, a calcitonin gene‐related peptide receptor antagonist, in healthy adults and patients with migraine

    Population pharmacokinetic modeling of zavegepant, a calcitonin gene‐related peptide receptor antagonist, in healthy adults and patients with migraine by Craig M. Comisar, Jose Francis, Jim H. Hughes, Rajinder Bhardwaj, Richard Bertz, Jing Liu

    Published 2025-01-01
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  13. 13
    Nonlinear mixed‐effects modeling as a method for causal inference to predict exposures under desired within‐subject dose titration schemes

    Nonlinear mixed‐effects modeling as a method for causal inference to predict exposures under desired within‐subject dose titration schemes by Christian Bartels, Martina Scauda, Neva Coello, Thomas Dumortier, Björn Bornkamp, Giusi Moffa

    Published 2025-01-01
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  14. 14
    Vancomycin population pharmacokinetic models: Uncovering pharmacodynamic divergence amid clinicobiological resemblance

    Vancomycin population pharmacokinetic models: Uncovering pharmacodynamic divergence amid clinicobiological resemblance by Peggy Gandia, Sahira Chaiben, Nicolas Fabre, Didier Concordet

    Published 2025-01-01
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  15. 15
    PBPK modeling: What is the role of CYP3A4 expression in the gastrointestinal tract to accurately predict first‐pass metabolism?

    PBPK modeling: What is the role of CYP3A4 expression in the gastrointestinal tract to accurately predict first‐pass metabolism? by Justine Henriot, André Dallmann, François Dupuis, Jérémy Perrier, Sebastian Frechen

    Published 2025-01-01
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