Tolerogenic Splenic IDO+ Dendritic Cells from the Mice Treated with Induced-Treg Cells Suppress Collagen-Induced Arthritis by Jie Yang, Yiming Yang, Huahua Fan, Hejian Zou

“…Moreover, the inhibitory activity of DCiTreg on CIA was lost following pretreatment with the inhibitor of indoleamine 2,3-dioxygenase (IDO). …”
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Mitochondrial Mayhem: How cigarette smoke induces placental dysfunction through MMS19 degradation by Pei Zhou, Feng Jin, Shenshen Yao, Ben Sun, Ni Sun, Hongbo Guan, Xiaomei Liu

“…This study aims to investigate the impact of CS on trophoblast cell proliferation and regulated cell death (RCD) by examining its interference with iron-sulfur cluster (ISC) proteins and the CIA pathway. Exposure to CS disrupted the cytosolic ISC assembly (CIA) pathway, downregulated ISC proteins, and decreased ISC maturation in the placenta of rats exposed to passive smoking. …”
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Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism by Yang Yang, Yang Yang, Qing Hong, Qing Hong, Xuehong Zhang, Zhenmin Liu, Zhenmin Liu

“…The gene expression levels of intestinal barrier proteins (occludin-1, MUC-2, and ZO-1) showed a significant increase (p < 0.05) in B. animalis BD400-treated CIA rats. The oral administration of B. animalis BD400 altered the composition of intestinal microorganisms in CIA rats at the phylum and genus levels, particularly affecting the genus HT002. …”
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Collagen Induced Arthritis in DBA/1J Mice Associates with Oxylipin Changes in Plasma by Min He, Eduard van Wijk, Ruud Berger, Mei Wang, Katrin Strassburg, Johannes C. Schoeman, Rob J. Vreeken, Herman van Wietmarschen, Amy C. Harms, Masaki Kobayashi, Thomas Hankemeier, Jan van der Greef

“…DBA/1J male mice (age: 6-7 weeks) were selected and randomly divided into two groups, namely, a CIA and a Ctrl group. The CIA mice were injected intraperitoneally (i.p.) with the joint cartilage component collagen type II (CII) and an adjuvant injection of lipopolysaccharide (LPS). …”
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Antigen-Specific Gene Therapy after Immunisation Reduces the Severity of Collagen-Induced Arthritis by Tove Eneljung, Sara Tengvall, Pernilla Jirholt, Louise Henningsson, Rikard Holmdahl, Kenth Gustafsson, Inger Gjertsson

“…We have developed a model of antigen-specific tolerance in collagen type II (CII) induced arthritis (CIA) using lentivirus-based gene therapy. The immunodominant epitope of CII was inserted into a lentivirus vector to achieve expression on the MHC class II molecule and the lentiviral particles were subsequently intravenously injected at different time points during CIA. …”
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Application of Surface Roughness Analysis on Micro–Computed Tomographic Images of Bone Erosion: Examples Using a Rodent Model of Rheumatoid Arthritis by Matthew D. Silva, Jason Ruan, Elizabeth Siebert, Anneli Savinainen, Bruce Jaffee, Lisa Schopf, Sudeep Chandra

“…In two studies of rat CIA, the surface roughness of the talus bone following 21 days of disease increased 559% and 486% from the control group. …”
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RhoA Promotes Synovial Proliferation and Bone Erosion in Rheumatoid Arthritis through Wnt/PCP Pathway by Ning Chen, Chao-Yue Diao, Xin Huang, Wei-Xing Tan, Ya-Bing Chen, Xin-Yu Qian, Jie Gao, Dong-Bao Zhao

“…Here, we not only explored the impact of RhoA on the proliferation and invasion of RA fibroblast-like synoviocytes (FLSs) but also elucidated its effect on mouse osteoclast and a mouse model of collagen-induced arthritis (CIA). Results showed that RhoA was overexpressed in RA and CIA synovial tissues. …”
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Disruption of Gut Microbiota and Associated Fecal Metabolites in Collagen-Induced Arthritis Mice During the Early Stage by Wu D, Yin M, Cao D, Zhang X, Zhu Y, Wei Y, Li Y, Wen C, Zhou J

“…A combination of 16S rRNA sequencing, untargeted metabolomics and targeted short-chain fatty acids (SCFAs) analysis were employed to comprehensively investigate the alterations of gut microbiota and fecal metabolites in CIA during the pre-RA stage.Results: 20 days after the initial collagen immunization, CIA mice showed immune responses without joint symptoms, alongside gut microbiota disruption. …”
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Ethyl Caffeate Ameliorates Collagen-Induced Arthritis by Suppressing Th1 Immune Response by Shikui Xu, Aixue Zuo, Zengjun Guo, Chunping Wan

“…The present study was designed to assess the antiarthritic potential of ECF in collagen-induced arthritis (CIA) and explore its underlying mechanism. Methods. …”
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Cresp®: transforming the landscape of chemotherapy-induced anemia - a comprehensive retrospective real-world analysis in 523 Indian patients by MV Chandrakanth, Vivek Agarwala, Pranav Sopory, Himadri Nayak, Purvish M. Parikh, Minakshi Roy, Rajib De, Pradeep Narayan, Anjuli Tuladhar Barai, Kaustav Mandal, Moinak Basu, Subhabrata Kumar, Rajdeep Singh Uppal, Syed Mujtaba Hussain Naqvi, Rohit Desai

“…Chemotherapy-induced anemia (CIA) diminishes the quality of life, causing fatigue, breathlessness, and a decline in the performance status. …”
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ANÁLISE COMPARATIVA DOS RELATÓRIOS SOCIOAMBIENTAIS DE 2013 E 2016 DE EMPRESAS PARTICIPANTES DO PROGRAMA “EM BOA COMPANHIA” by Deisy Cristina Corrëa Igarashi, Adriel da Costa Benati, Flávia Mayara Segate, Bárbara Johann Borges, Wagner Igarashi

“…No eixo de “Parceria” a Cia. Suzano de Papel e Celulose deixou de apresentar ações no ano de 2016, enquanto a Klabin S/A passou a ter ações vinculadas ao eixo e a Duratex S.A. manteve-se atuando em uma das frentes. …”
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Un modelo de equilibrio general para la fijación de precios del gas natural en México by Dagobert L. Brito, Juan Rosellón

“…La Comisión Reguladora de Energía de México ha implantado una regla deen la ce ha cia atrás para unir el pre cio del gas na tu ral me xi ca no al pre cio delgas na tu ral de Te jas. …”
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Dissecting the Molecular Mechanism of Wang-Bi Capsule in the Treatment of Experimental Rheumatoid Arthritis Based on Synovial Tissue Proteomic Analysis by Haiyang Shu, Yingjie Shi, Li Li, Ning Zhao, Cheng Lu, Aiping Lu, Xiaojuan He

“…In this study, collagen-induced arthritis (CIA) rats were used to observe the therapeutic effect of WB used at different time points, and the proteomic analysis of synovial tissue was applied to reveal its basic molecular mechanisms. …”
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Intra-Articular Injection of Human Synovial Membrane-Derived Mesenchymal Stem Cells in Murine Collagen-Induced Arthritis: Assessment of Immunomodulatory Capacity In Vivo by Minglu Yan, Xin Liu, Qiujie Dang, He Huang, Fan Yang, Yang Li

“…The efficacy of SM-MSCs in CIA was evaluated clinically and histologically. …”
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Dysregulation of Innate Lymphoid Cells in Patients with Active Rheumatoid Arthritis and Mice with Collagen-Induced Arthritis by Fengfan Yang, Xing Luo, Wenxiao Zhu, Jia Li, Zhaohui Zheng, Ping Zhu

“…Our results indicate that dysregulation of ILCs occurs during the pathogenesis of RA and CIA.…”
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Las rentas de las exportaciones y la política comercial con oligopolio by Marcos Ávalos, José Carlos Ramírez

“…Para una industria oligopólica, este ensayo analiza la manera cómo la políti -ca comercial puede depender de la naturaleza competitiva de los mercados.Estudiamos los efectos de las fusiones nacionales y extranjeras en la políticaco mer cial óp ti ma del país de re fe ren cia y en las ren tas de las ex por ta cio nes yel bienestar interno. …”
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Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy by Wenjun Li, Wenjun Li, Junjiang Sun, Susi Feng, Ariana La Rosa, Panli Zhang, Eveline Y. Wu, Richard Loeser, Chengwen Li, Chengwen Li, Chengwen Li

“…The levels of total immunoglobulin and anti-collagen specific antibodies were lower in AAV8/shPD-L1 treated CIA mice than those in controls. The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. …”
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Peptidylarginine Deiminase 2 in Murine Antiviral and Autoimmune Antibody Responses by Aisha M. Mergaert, Michael F. Denny, Brock Kingstad-Bakke, Mandar Bawadekar, S. Janna Bashar, Thomas F. Warner, Marulasiddappa Suresh, Miriam A. Shelef

“…In this study, we evaluated a requirement for PAD2 in the antibody response in collagen-induced arthritis (CIA), a T and B cell-driven murine model of rheumatoid arthritis, and in the protective antibody response to murine influenza infection. …”
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Cellulase-Assisted Extraction, Characterization, and Bioactivity against Rheumatoid Arthritis of Astragalus Polysaccharides by Ling Cao, Mi Yu, Chonghui Wang, Yunhui Bao, Minghui Zhang, Ping He, Yan Zhang, Tingting Yang, Lulu Li, Gang Li, Yun Gong

“…Then their therapeutic effects and possible mechanism against RA were explored using type II collagen-induced arthritis (CIA) rat model. APS could significantly reduce paw swelling, serum concentration of IL-1β and TNF-α, and the expression levels of NF-κB-p65 and IκBα in synovial membranes in CIA rats. …”
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Violência contra crianças e adolescentes: notificação ou invisibilidade? by Mora Kissi de Oliveira Nascimento, Gláucia Helena Araújo Russo

“…Foi identificado que a violên- cia contra crianças e adolescentes é invisibilizada nos serviços de saú- de, principalmente na atenção básica. …”
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