Development an Inflammation-Related Factor-Based Model for Predicting Organ Failure in Acute Pancreatitis: A Retrospective Cohort Study by Yunpeng Peng, Xiaole Zhu, Chaoqun Hou, Chenyuan Shi, Dongya Huang, Zipeng Lu, Yi Miao, Qiang Li

“…Univariate analytic data revealed that IL6, IL8, IL10, MCP1, CD3+ CD4+ T lymphocytes, CD19+ B lymphocytes, PCT, APACHE II score, and RANSON score were potential predictors for AP organ failure, and IL6 (P=0.038), IL8 (P=0.043), and CD19+B lymphocytes (P=0.045) were independent predictors according to further multivariate analysis. …”
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Enhanced AC/DC optimal power flow via nested distributed optimization for AC/VSC-MTDC hybrid power systems by Haixiao Li, Pedro P. Vergara, Robert Dimitrovski, Hongjin Du, Aleksandra Lekić

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Natural Killer Cells from Malignant Pleural Effusion Are Endowed with a Decidual-Like Proangiogenic Polarization by Annalisa Bosi, Silvia Zanellato, Barbara Bassani, Adriana Albini, Alessandra Musco, Maria Cattoni, Matteo Desio, Elisa Nardecchia, Davide Giuseppe D’Urso, Andrea Imperatori, Lorenzo Dominioni, Douglas M. Noonan, Lorenzo Mortara, Antonino Bruno

“…NK cells from pleural effusion of patients with inflammatory conditions (iPE, n = 18), primary tumor (ptPE, n = 18), and metastatic tumor (tmPE, n = 27) acquired the CD56brightCD16− phenotype. NK cells from both ptPE and tmPE showed increased expression for the CD49a and CD69 decidual-like (dNK) markers and decreased levels of the CD57 maturation marker. …”
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Targeting Siglec-E facilitates tumor vaccine-induced antitumor immunity in renal carcinoma by Yuchen Zhang, Junnian Zheng, Li Sun, Guangya Zhao, Yingxiang Shao, Bowen Lu, Jiage Ding, Yanyan Zheng, Renjin Chen, Dafei Chai, Jiawei Wang, Zichun Zhang, Xiaohui Xie

“…Immunization with Ad-Siglec-E/CAIX promoted the induction and maturation of CD11c+ dendritic cells and their subsets, which in turn enhanced tumor-specific CD8+ T cell immune responses, as evidenced by increased CD8+ T cell proliferation and CTL activity. …”
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Prognostic value of tumor‐infiltrating lymphocytes and PD‐L1 expression in esophageal squamous cell carcinoma by Jie Hu, Takeshi Toyozumi, Kentaro Murakami, Satoshi Endo, Yasunori Matsumoto, Ryota Otsuka, Tadashi Shiraishi, Shinichiro Iida, Hiroki Morishita, Tenshi Makiyama, Yuri Nishioka, Masaya Uesato, Koichi Hayano, Akira Nakano, Hisahiro Matsubara

“…Immunohistochemical analysis and multiplex immunofluorescence for CD4, CD8, CD25, FOXP3, and PD‐L1 in the tumor were used to identify multiple tumor‐infiltrating immune cells (TIIC), Tregs, and TC. …”
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Heterogeneous reactions in a HFCVD reactor: simulation using a 2D model by Xochitl Aleyda Morán Martínez, José Alberto Luna López, Zaira Jocelyn Hernández Simón, Gabriel Omar Mendoza Conde, José Álvaro David Hernández de Luz, Godofredo García Salgado

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Adaptive Immune Response to Model Antigens Is Impaired in Murine Leukocyte-Adhesion Deficiency-1 Revealing Elevated Activation Thresholds In Vivo by Thorsten Peters, Wilhelm Bloch, Oliver Pabst, Claudia Wickenhauser, Claudia Uthoff-Hachenberg, Susanne V. Schmidt, Georg Varga, Stephan Grabbe, Daniel Kess, Tsvetelina Oreshkova, Anca Sindrilaru, Klaus Addicks, Reinhold Förster, Werner Müller, Karin Scharffetter-Kochanek

“…Absence of β2 integrins (CD11/CD18) leads to leukocyte-adhesion deficiency-1 (LAD1), a rare primary immunodeficiency syndrome. …”
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A De Novo Frameshift Variant in SMC1A Causes Non‐Classic Cornelia de Lange Syndrome With Epilepsy: A Case Report and Literature Review by Ying Yang, Liqing Chen, Zhenzhen Wang, Yaling Ding, Yan Liu

“…ABSTRACT Background Cornelia de Lange syndrome (CdLS) is a multisystem genetic disorder. Although individuals with variants in the SMC1A gene are less commonly seen in CdLS, they exhibit a high incidence of epilepsy and atypical phenotypic variability. …”
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The Hormesis effect of cadmium on Panax notoginseng and corresponding impact on the rhizosphere microorganism by Mingpeng Liu, Xuanxiang Du, Mulan Wang, Yuewen Huo, Yanbo Zeng, Jingheng Wu, Xin Ying, Fugang Wei, Li Liu, Jianguo Tang

“…At high concentrations, Cd inhibits the overall growth and metabolism of notoginseng. …”
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Estudio preliminar de los problemas de salud mental presentes en profesionales de la salud de la región centro de Tamaulipas. by Patricia Rivera-Vázquez, Jorge Alfredo Manriquez-Vazquez, Taide Gabriela González-Lara, Rafael Gallegos-García, Alfredo Sánchez-González, Martha Carmina Escamilla-García, Dionisio Enrique Martínez-Saldaña, Pedro Luis Mendoza-Múzquiz, Araní Casillas-Ramírez

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Tregs levels and phenotype modifications during Amyotrophic Lateral Sclerosis course by Elisabetta Zucchi, Elisabetta Zucchi, Federico Banchelli, Cecilia Simonini, Sara De Biasi, Ilaria Martinelli, Giulia Gianferrari, Giulia Gianferrari, Domenico Lo Tartaro, Andrea Cossarizza, Andrea Cossarizza, Roberto D’Amico, Roberto D’Amico, Jessica Mandrioli, Jessica Mandrioli

“…Additionally, we explored whether measures of ALS progression, such as the decline over time in the revised ALS Functional Rating Scale (ALSFRS-r) or forced vital capacity (FVC) correlated Treg levels and whether Treg phenotype varied during the course of ALS.MethodsTotal Tregs (detected by CD3, CD4, FoxP3, CD25, and CD127) were quantified at five time points over 54 weeks in 21 patients in the placebo arm of the RAP-ALS trial; next they were characterized for the expression of surface markers including CD38, CD39, CXCR3, and PD1. …”
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A novel approach to digital characterisation of Tertiary Lymphoid Structures in colorectal cancer by Luis Munoz-Erazo, Luis Munoz-Erazo, Saem Mul Park, Saem Mul Park, Shelly Lin, Shelly Lin, Chun-Jen J. Chen, Chun-Jen J. Chen, Lisa Y. Y. Zhou, Lisa Y. Y. Zhou, Janet L. Rhodes, Janet L. Rhodes, Taesung Jeon, Sonya Fenton, John L. McCall, Roslyn A. Kemp, Roslyn A. Kemp, P. Rod Dunbar, P. Rod Dunbar

“…Multiplexed staining for CD20, CD3, CD8, Foxp3 and Ki-67 enabled us to identify B-cells, CD8+ T-cells, Foxp3– CD4 T-cells, and Foxp3+ CD4 Tcells in all sections, and quantify both the presence of these cell subsets in lymphocytic clusters and their degree of proliferation within those clusters.ResultsIn total we identified 524 lymphocytic clusters with morphology consistent with TLS. …”
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Ambulatory Surgery for Perianal Crohn’s Disease: Study of Feasibility by S. Sibio, A. Di Giorgio, M. Campanelli, S. Di Carlo, A. Divizia, C. Fiorani, R. Scaramuzzo, C. Arcudi, G. Del Vecchio Blanco, L. Biancone, G. Sica

“…One-third of Crohn’s disease (CD) patients present perianal fistula. The gold standard in the diagnosis and treatment of symptomatic perianal disease (PAD) in CD is the exploration of the anal canal and distal rectum under anesthesia (EUA). …”
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Клініко-імунологічний підхід до лікування інфекції акушерської хірургічної рани в породілей by A.B. Рrуlutska, L.I. Martynova, S.O. Avramenko, O.B. Yaroshchuk, D.О. Govsіeіev

“…Для оцінювання стану загального імунітету підраховано загальну кількість Т-лімфоцитів (CD3+), їхніх імунорегуляторних субпопуляцій - Т-хелперів/індукторів (CD4+) і Т-супресорів/кілерів (CD8+), кількість В-лімфоцитів (CD22+), NK-клітин (CD16+), вирахувано імунорегуляторний індекс (CD4+/CD8+). …”
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Plateau hypoxia improves tumor immune microenvironment and inhibits subcutaneous tumor growth of colorectal cancer by ZHAO Sijie, WANG Meng, GAO Yuan

“…Additionally， the percentage of CD4+ T cells was significantly reduced （48.70% vs 41.93%， P<0.05）， whereas that of CD8+ T cells was obviously increased （41.25% vs 51.18%， P<0.05）， along with a notable rise in the proportions of IFN-γ+ T， IFN-γ+ CD4+ T and IFN-γ+ CD8+ T cells （28.58% vs 59.65%， 23.33% vs 53.65%， 36.9% vs 66.48%， P<0.01）. …”
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Synthesis and Characterization of Metal Sulfides Nanoparticles/Poly(methyl methacrylate) Nanocomposites by Peter A. Ajibade, Johannes Z. Mbese

“…The ZnS nanoparticles in PMMA have average crystallite sizes of 4–7 nm while the CdS has particle size of 10 nm and HgS has crystallite sizes of 8–20 nm. …”
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The influence of 2- chlorodeoxyadenosine in combination with tumour necrosis factor-α or its mutein on murine leukaemias L1210 and P388 by J. Góra-Tybor, K. Warzocha, T. Robak

“…Groups of mice with leukaemia L1210 and P388 receiving 2-CdA combined with TNFα had shorter survival times than animals treated with these agents separately. …”
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CAR-T CELL THERAPY FOR FOLLICULAR LYMPHOMAS by Ugo Testa, Francesco D'Alò, Elvira Pelosi, Germana Castelli, Giuseppe Leone

“…Chimeric antigen receptor (CAR)-T cell therapy targeting B-cell antigens, such as CD19 or CD20, is emerging as an efficacious treatment for R/R follicular lymphoma patients, particularly for those with early relapse and refractory to alkylating agents and to anti-CD20 monoclonal antibodies, resulting in a high rate of durable responses in a high proportion of patients.   …”
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Tiger-Striped PASH: Recognition of a Unique Morphology Allows for a Zippered-Up Diagnosis of Pseudoangiomatous Stromal Hyperplasia of Breast by Mohamad Sakibuzzaman, Ryan W. Kendziora, Toshi Ghosh, Malvika H. Solanki, Amy Lynn Conners, Lisa J. Ahlberg, Charles D. Sturgis

“…Immunohistochemistry (IHC) studies may also help to confirm a diagnosis of PASH, with the spindled cells marking positively with CD34 and PR while demonstrating no reactivity with more specific endothelial antigens such as CD31 and ERG. …”
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Smoking and Diseases of the Gastrointestinal System: An Epidemiological Review with Special Reference to Sex Differences by Mary Jane Ashley

“…There is growing evidence that cigarette smoking is a risk factor for Crohn's disease (CD) in both women and men. …”
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