Review of celiac disease in the pediatric population by Aleksandra Strawińska, Maria Wydro, Magdalena Grotowska, Martyna Łukasiewicz

“…Celiac disease (CD) is a chronic autoimmune disease triggered by the ingestion of gluten in genetically predisposed individuals, primarily those with HLA-DQ2 and HLA-DQ8 haplotypes. …”
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Mechanisms of reduced sensitization by extensive hydrolysis of milk protein concentrate: Impact on the immune response of Th1/Th2 and Treg/Th17 cells in mice by Qiang Cui, Jianjun Cheng, Mingruo Guo

“…The mice in the control MPC group highly expressed FcεRI+CD117+ mast cells (22.25%), peripheral blood B cells (2.91%), and CD3+CD8+ T cells (8.65%). …”
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Therapeutic Potential of Clove Oil in Mitigating Cadmium-Induced Hepatorenal Toxicity Through Antioxidant, Anti-Inflammatory, and Antiapoptotic Mechanisms by Inas M. Elgharib, Fatma M. Abdelhamid, Gehad E. Elshopakey, Hatem Sembawa, Talat A. Albukhari, Waheed A. Filimban, Rehab M. Bagadood, Mohamed E. El-Boshy, Engy F. Risha

“…Hazardous heavy metals, particularly cadmium (Cd), are widely distributed in the environment and cause oxidative stress in various animal and human organs. …”
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Evaluation of Serum Leucine-Rich Alpha-2 Glycoprotein as a New Inflammatory Biomarker of Inflammatory Bowel Disease by Tetsuhiro Yoshimura, Keiichi Mitsuyama, Ryosuke Sakemi, Hidetoshi Takedatsu, Shinichiro Yoshioka, Kotaro Kuwaki, Atsushi Mori, Shuhei Fukunaga, Toshihiro Araki, Masaru Morita, Kozo Tsuruta, Hiroshi Yamasaki, Takuji Torimura

“…Studies on serum leucine-rich alpha-2 glycoprotein (LRG) in inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), are scarce; the methods for estimating disease activity are less established, particularly for CD. …”
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Determination of arsenic and cadmium uptake by rice from topsoil by Desheng Yang, Zhechuan Liu, Wenqi Zhao, Ting Du, Shengyang Fan, Zhuang Xiong, Shaobing Peng, Xiaoxiao Li, Fei Wang

“…TR also decreased shoot As and Cd accumulation by 30.7% and 67.8% at maturity, with topsoil at 12–15 cm depth contributing an average of 2372 μg As m−2 (30.1%) and 138 μg Cd m−2 (66.1%) to total uptake of As and Cd, respectively. …”
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Immune cells in thyroid adenoma and carcinoma: uncovering a hidden value of assessing tumor-host interplay and its potential application in thyroid cytopathology by Iryna Omelianenko, Iryna Omelianenko, Nazarii Kobyliak, Nazarii Kobyliak, Tetyana Falalyeyeva, Tetyana Falalyeyeva, Oleksii Seleznov, Pavlina Botsun, Lyudmila Ostapchenko, Oleksandr Korotkyi, Liudmyla Domylivska, Olena Tsyryuk, Galyna Mykhalchyshyn, Tetiana Shapochka, Oksana Sulaieva, Oksana Sulaieva

“…Besides, the expression of STAT6 and SMAD4 as potential regulators of TIME was evaluated in the study.ResultsTC demonstrated an immune-rich profile representing abundant tumor-associated CD8+ lymphocytes, CD68 and CD163+ macrophages. In contrast, TA represented mostly a low immune cell infiltration. …”
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Early Endoscopic Outcomes After Risankizumab Are Associated With Fewer Hospitalizations and Surgeries in Crohn’s Disease by Brian G. Feagan, Jean-Frederic Colombel, Remo Panaccione, Stefan Schreiber, Marc Ferrante, Koji Kamikozuru, Christopher Ma, Wan-Ju Lee, Jenny Griffith, Namita Joshi, Kristina Kligys, Jasmina Kalabic, Si Xuan, Marla Dubinsky

“…Background and Aims: We evaluated the association between endoscopic outcomes following risankizumab induction and subsequent rates of hospitalization and surgery through 52 weeks of risankizumab (both doses) maintenance therapy in patients with Crohn’s disease (CD). Methods: Patients with moderately to severely active CD and clinical response to 12-week risankizumab induction were rerandomized to continued therapy or drug withdrawal in the phase 3 FORTIFY maintenance trial. …”
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Age influences the circulating immune profile in pediatric sepsis by Grace Fisler, Grace Fisler, Grace Fisler, Mariana R. Brewer, Mariana R. Brewer, Mariana R. Brewer, Omar Yaipen, Clifford S. Deutschman, Clifford S. Deutschman, Clifford S. Deutschman, Matthew D. Taylor, Matthew D. Taylor, Matthew D. Taylor

“…Children with sepsis had more regulatory CD4+ T cells and memory CD4+ T cells and less CD4+IL-10+ and CD8+T-bet+ T cells than healthy children. …”
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Lung-delivered IL-10 therapy elicits beneficial effects via immune modulation in organic dust exposure-induced lung inflammation by Aaron D. Schwab, Todd A. Wyatt, Amy J. Nelson, Angela Gleason, Rohit Gaurav, Debra J. Romberger, Jill A. Poole

“…IL-10 therapy reduced ODE-associated expression of antigen presentation (MHC Class II, CD80, CD86) and inflammatory (Ly6C) markers and increased anti-inflammatory CD206 expression on CD11cintCD11b+ cells. …”
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Imaging Flow Cytometric Identification of Chromosomal Defects in Paediatric Acute Lymphoblastic Leukaemia by Ana P. A. Simpson, Carly E. George, Henry Y. L. Hui, Ravi Doddi, Rishi S. Kotecha, Kathy A. Fuller, Wendy N. Erber

“…After identifying the leukaemic population based on immunophenotype (i.e., expression of CD34, CD10, and CD19 antigens), we assessed for copy numbers of loci for the centromeres of chromosomes 4 and 21 and the <i>ETV6</i> and <i>RUNX1</i> regions using fluorophore-labelled DNA probes in more than 1000 cells per sample. …”
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Cathepsin-D and outcomes in peripartum cardiomyopathy: Results from IPAC by Vincenzo B. Polsinelli, Karen Hanley-Yanez, Charles F. McTiernan, Kalgi Modi, Jennifer Haythe, Hal Skopicki, Uri Elkayam, Leslie T. Cooper, Jr, James D. Fett, Dennis M. McNamara

“…Objective: Evaluate the relationship of cathepsin-D (CD) on disease severity and clinical outcomes for women with peripartum cardiomyopathy. …”
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Dietary Choline Deprivation Exacerbates Kidney Injury in Streptozotocin-Induced Diabetes in Adult Rats by Ahmed W. Al-Humadi, Carel W. le Roux, Neil G. Docherty, Werd Al-Najim, Martin Tze Wah Kueh, Andreas C. Lazaris, Charis Liapi

“…<b>Methods</b>: Twenty-four adult male Wistar rats were divided into four groups: control (C), nondiabetic Ch-deprived (CD), diabetic (DM), and diabetic Ch-deprived (DM + CD). …”
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Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia by Ashley G. Zhao, Kiran Shah, Julien Freitag, Brett Cromer, Huseyin Sumer

“…We confirmed by flow cytometry the presence of cell surface markers CD105, CD73, and CD90 and lack of expression of CD45, CD34, CD14, and CD19 across all conditions. …”
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Th9 Cells in Peripheral Blood Increased in Patients with Immune-Related Pancytopenia by Qing Shao, Yangyang Wang, Zhaoyun Liu, Hui Liu, Yihao Wang, Yang Zhao, Lijuan Li, Rong Fu

“…They were negatively correlated with hemoglobin, red blood cell, white blood cell, and platelet counts and positively correlated with the percentage of CD19+B cells and CD5+CD19+/CD19+B cells, respectively. …”
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The role of natural exosomes from SHED-MSC in immunoregulation of M0/M1 polarized macrophage cells by Ali Fallah, Abasalt Hosseinzadeh Colagar, Ayyoob Khosravi, Ayyoob Khosravi, Azadeh Mohammad-Hasani, Azadeh Mohammad-Hasani, Mohsen Saeidi, Mohsen Saeidi

“…This study focused on exosomes derived from stem cells of human exfoliated deciduous teeth (SHED-MSC-EXOs) and their role in managing the balance of immunoregulatory macromolecules that play a role in the underlying immunoregulatory mechanisms in THP-1-derived M0/M1 macrophage cells.MethodsFlow cytometry confirmed the expression of CD14, CD68, CD80, and CD86 markers in these macrophages. …”
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Fabry cardiomyopathy: Gb3‐induced auto‐reactive panmyocarditis requiring heart transplantation by Andrea Frustaci, Maurizio Scarpa, Rosalia Maria da Riol, Chiara Agrati, Nicoletta Finato, Romina Verardo, Claudia Grande, Cristina Chimenti, Concetta Di Nora, Matteo Antonio Russo, Ugolini Livi

“…PBMC were stained using the monoclonal antibodies CD3‐V500, CD4‐V450, CD8‐APCcy7, CD45RO‐PerCPcy5.5 and CD27‐FITC from BD Biosciences and CD56‐PC7 from Bekman Coulter. …”
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Annexin V+ Microvesicles in Children and Adolescents with Type 1 Diabetes: A Prospective Cohort Study by Vibeke Bratseth, Hanna D. Margeirsdottir, Gemma Chiva-Blanch, Martin Heier, Svein Solheim, Harald Arnesen, Knut Dahl-Jørgensen, Ingebjørg Seljeflot

“…In the type 1 diabetes group, the total AV+, tissue factor-expressing AV+/CD142+, neutrophil-derived AV+/CD15+ and AV+/CD45+/CD15+, and endothelial-derived AV+/CD309+ and CD309+/CD34+ cMVs were inversely correlated with HbA1c (r=‐0.437, r=‐0.515, r=‐0.575, r=‐0.529, r=‐0.416, and r=‐0.445, respectively; all p≤0.01), however, only at inclusion. …”
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Biological insights into alleviating heavy metal toxicity through the simultaneous supply of biochar biofilters derived from the Mikania micrantha and molybdenum nanoparticles by Muhammad Shoaib Rana, Hongyu Chen, Shiwen Deng, Muhammad Imran, Yousif Abdelrahman Yousif Abdellah, Wanting Li, Jiayu Lin, Jiaxi Li, Ruilong Wang

“…Abstract Cadmium (Cd) contamination in the environment is widespread, making it crucial to reduce Cd accumulation in cereal crops like wheat. …”
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Comparative immobilization of lead, cadmium, and copper in soil using dead bacterial biomass and graphitic carbon nitride nanomaterials by Asifa Farooqi, Ejaz ul Haq, Hooria Ikram Raja, Hafiz Abdul Malik, Yousaf Shad Muhammad, Syed Hamza Safeer, Sohail Yousaf, Maximilian Lackner

“…Cu showed the highest adsorption (57 %) followed by Cd and Pb. The Cd adsorption increased from 35 % at Cd_125 to ∼55 % at Cd_275. …”
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Application of immunohistochemical markers in mycosis fungoides by SHAO Kaixin, LIU Xiangjun, TANG Zhenzhen

“…Common markers such as CD4, CD8, CD20, and CD30 have different expression patterns in mycosis fungoides. …”
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