Valsartan in Combination with Tripterygium Glycosides Protects against Chronic Nephritis via the Toll-Like Receptor 4 Pathway by Jiabao Dong, Duo Huang, Ling Jing, Mengmeng Wu

“…., IL-1β and IL-8), and the proportion of T lymphocyte subpopulations (CD4+ and CD8+) were detected in chronic nephritis patients before and after treatment with valsartan alone or valsartan combined with tripterygium glycosides. …”
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Characterization of the Immune Response Induced by a Commercially Available Inactivated Bluetongue Virus Serotype 1 Vaccine in Sheep by Ana Cristina Pérez de Diego, Pedro José Sánchez-Cordón, Ana Isabel de las Heras, José Manuel Sánchez-Vizcaíno

“…This specific antibody response was associated with a significant increase in B lymphocytes confirmed by flow cytometry, while significant increases were not observed in T lymphocyte subpopulations (CD4+, CD8+, and WC1+), CD25+ regulatory cells, or CD14+ monocytes. …”
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Fecal Lactoferrin: Reliable Biomarker for Intestinal Inflammation in Pediatric IBD by Stephan Buderus, James H. Boone, Michael J. Lentze

“…In CD patients the endoscopic severity score SES-CD was correlated with the FL levels. …”
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CTLA-4 Engagement Inhibits Th2 but not Th1 Cell Polarisation by Vanessa Ubaldi, Lucia Gatta, Luigia Pace, Gino Doria, Claudio Pioli

“…In the present work, we investigated the role of CTLA-4 in T helper cell subset differentiation. Naïve CD4+ cells were stimulated with anti-CD3 and anti-CD28 mAbs in the presence of either IL-12 or IL-4 to induce polarisation to Th1 or Th2 cells, respectively. …”
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EBV-Negative Monomorphic B-Cell Posttransplant Lymphoproliferative Disorder with Marked Morphologic Pleomorphism and Pathogenic Mutations in ASXL1, BCOR, CDKN2A, NF1, and TP53 by Agata M. Bogusz

“…By immunostaining, the malignant cells were immunoreactive for CD45, CD20, CD79a, PAX5, BCL6, MUM1, and p53 and negative for CD15, CD30, latent membrane protein 1 (LMP1), and EBV-encoded RNA (EBER). …”
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Ruxolitinib synergizes with regulatory T cells to improve inflammation but has no added benefits in decreasing albuminuria in SLE by Mi-Ae Lyu, Ximing Tang, Maria Gabriela Raso, Meixian Huang, Ke Zeng, Tara Sadeghi, Christopher R. Flowers, Simrit Parmar

“…BackgroundUmbilical cord blood (UCB)-derived CD4+CD25+CD127low regulatory T cells (Tregs) can decrease albuminuria and anti-dsDNA IgG in systemic lupus erythematosus (SLE). …”
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Reducing Cadmium in Cocoa (Theobroma cacao) Cultivars: Analysis of Advantages and Limitations of Different Strategies and Their Potential Application in Colombia by Claudia Lucumí Villegas, Nathali Jiménez Quiroga, Andrés Dávalos, Camila Pizano

“…Consequently, cocoa exports in countries such as Colombia could be threatened due to the high concentrations of Cd present in its soils. Therefore, there is a clear need for developing techniques that reduce Cd in the beans and in soils. …”
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Three Successful Pregnancies in a Patient with Recurrent Cushing’s Disease by W. Benothman, G. Saad, M. Kacem, K. Ach

“…The association of pregnancy and Cushing’s disease (CD) is rare. A 28-year-old woman was admitted for clinical suspicion of Cushing’s syndrome. …”
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Association Analysis of ULK1 with Crohn’s Disease in a New Zealand Population by Angharad R. Morgan, Wen-Jiun Lam, Dug-Yeo Han, Alan G. Fraser, Lynnette R. Ferguson

“…The gene ULK1 is an excellent candidate for Crohn’s disease (CD) due to its role in autophagy. A recent study provided evidence for the involvement of ULK1 in the pathogenesis of CD (Henckaerts et al., 2011). …”
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Interstitial Mycosis Fungoides: An Unusual Mimic of Interstitial Granuloma Annulare Not to Miss by Neha Singh, Kiley K. Fagan, Douglas J. Grider

“…Immunohistochemistry staining revealed the atypical lymphocytes to be positive for CD3 and CD8 and negative for CD4 and CD7, an aberrant immunoprofile. …”
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Synthesis, crystal structure and thermal properties of poly[di-μ-bromido-(μ-2,5-dimethylpyrazine)cadmium(II)] by Christian Näther

“…The title compound, [CdBr2(C6H8N2)]n, was prepared by the reaction of cadmium bromide with 2,5-dimethylpyrazine in water. …”
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Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature by Prashant Mane, Prashant Ramteke, Anand Singh, Ajay Gogia, Saumyaranjan Mallick

“…Partial gastrectomy done and histopathology showed transmural infiltration by intermediate size atypical lymphoid cells which are immunopositive for CD3, CD56, TIA, EBV-encoded RNA (EBER) and negative for CD4, CD8, CD20. …”
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A Subgroup of First-Degree Relatives of Crohn's Disease Patients Shows a Profile of Inflammatory Markers in the Blood Which is More Typical of Crohn's Disease Patients Than of Norm...

“…The hematological profile of FDRs showed values between the controls and CD patients with ten FDRs that their parameters matched those of CD patients and significantly different from other FDRs. …”
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Levels of Pathogenic Th17 and Th22 Cells in Patients with Rheumatoid Arthritis by Marlen Vitales-Noyola, Berenice Hernández-Castro, Diana Alvarado-Hernández, Lourdes Baranda, Sofía Bernal-Silva, Carlos Abud-Mendoza, Perla Niño-Moreno, Roberto González-Amaro

“…We found significant enhanced levels of total Th17 lymphocytes (defined as CD4+IL-17+) as well as enhanced numbers of their pathogenic (defined as CD4+CXCR3+IL-17+IL-22+CD243+CD161+IFN-γ+IL-10-) and nonpathogenic (CD4+CXCR3+IL-17+IL-22-CD243-CD161-IFN-γ-IL-10+) cell subsets in patients with RA. …”
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人脐带间充质干细胞分离扩增方法的优化

“…2×105个hUC-MSCs用LD-Mesen和LG-DMEM两种体系培养12d后，扩增所得的细胞数分别为(14.86±0.08)×106和(5.08±0.08)×106，二者有显著统计学差异（P=1.38×10-8)。hUC-MSCs高表达CD73、CD105、CD90、CD29、CD44，不表达CD31、CD34、CD45、HLA-DR；并可向成骨细胞及脂肪细胞诱导分化。…”
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Choroidal Detachment after XEN Gel Stent Implantation by Carlo Alberto Cutolo, Letizia Negri, Sara Olivari, Francesca Cappelli, Carlo Enrico Traverso, Michele Iester

“…The purpose of this study is to estimate the incidence of choroidal detachment (CD) after XEN gel stent implant surgery and to evaluate the associated factors. …”
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Corneal Clarity and Visual Outcomes after Small-Incision Lenticule Extraction and Comparison to Femtosecond Laser-Assisted In Situ Keratomileusis by Apostolos Lazaridis, Konstantinos Droutsas, Walter Sekundo, Michael Petrak, Stephan Schulze

“…Associations of postoperative CD values with the lenticule thickness and ablation depth were examined. …”
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Prevalence and predictors of severe Crohn’s disease at a tertiary hospital in South Africa by C Gounden, V Naidoo, Y Moodley

“…Conclusion Most patients with CD developed SCD within 1 year of their CD diagnosis. …”
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The Development and Applications of a Dual Optical Imaging System for Studying Glioma Stem Cells by Po-An Tai MD, PhD, Yen-Lin Liu MD, PhD, Ya-Ting Wen MD, Chien-Min Lin MD, PhD, Thanh-Tuan Huynh MD, PhD, Michael Hsiao DVM, PhD, Alexander T. H. Wu PhD, Li Wei MD, PhD

“…A better understanding of GSC biology is essential for developing more effective interventions. We established a CD133 promoter-driven dual reporter, expressing green fluorescent protein (GFP) and firefly luciferase (CD133-LG), capable for in vitro and in vivo imaging of CD133+ GSCs. …”
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Microbial diversity and metabolomics analysis of colon contents exposed to cadmium and polystyrene microplastics by Dechun Chen, Liyu Pan, Xuan Ran, Junyu Huang, Xiaohua Teng, Falong Yang, Haifeng Liu

“…In order to explore the damage mechanism of cadmium and cadmium combined microplastic on the colon of mice, 60 mice were divided into three groups: The control group (0.2 mL of saline), cadmium group (Cd group, 0.2 mL of 4.8 mg/kg/d CdCl2) and mixed group (Mix group, 0.2 mL of mixed solution containing 4.8 mg/kg/d CdCl2 and 10.0 mg/d MPs) were fed for 42 d. …”
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