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941
Scavenger Receptor Class B, Type I, a CD36 Related Protein in Macrobrachium nipponense: Characterization, RNA Interference, and Expression Analysis with Different Dietary Lipid Sources
Published 2016-01-01“…The scavenger receptor class B, type I (SR-BI), is a member of the CD36 superfamily comprising transmembrane proteins involved in mammalian and fish lipid homeostasis regulation. …”
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Safety and Efficacy of Subcutaneous Rituximab in Previously Untreated Patients with CD20+ Diffuse Large B-Cell Lymphoma or Follicular Lymphoma: Results from an Italian Phase IIIb Study
Published 2022-01-01“…The study included adult patients with CD20+ DLBCL or FL having received at least one full dose of IV RTX 375 mg/m2 during induction or maintenance. …”
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Potential of Co(II) and Cd(II) chelates of N′-(3-fluorobenzoyl)benzo[d]thiazole-2-carbohydrazide: Structural aspects, binding interactions, biological and molecular docking studies
Published 2025-01-01“…Anti-microbial studies carried out by pour plate method showed high activity for Cd(II)-MFBBTCH complex. Cytotoxicity of the compounds was performed for Hela and MCF cell lines by MTT assay. …”
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947
Efficacy and safety of anti-CD38 monoclonal antibodies-based therapy versus standard therapy in newly diagnosed multiple myeloma patients: a systematic review and meta-analysis
Published 2025-01-01“…Background: Anti-CD38 monoclonal antibodies (mAbs) have significantly changed the multiple myeloma treatment landscape. …”
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949
Combination of Metformin and Magnesium Citrate Reduces TNF-α, NF-κB p65, IL-6, CD4, and MMP-9 Expressions in Diabetic Model Rats
Published 2024-12-01“…TNF-α, NF-κB p65, IL-6, CD4, and MMP-9 expression levels were measured using enzyme-linked immunosorbent assay (ELISA). …”
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950
Anti-IL-22 Antibody Attenuates Acute Graft-versus-Host Disease via Increasing Foxp3+ T Cell through Modulation of CD11b+ Cell Function
Published 2018-01-01“…In the presence of Tregs and donor CD11b+ cells, IL-22Ab protected against aGVHD. In vitro Treg induction was more efficient when CD4+CD25− T cells differentiated in the presence of CD11b+ cells obtained from IL-22Ab-treated GVHD mice, compared with cocultured untreated control cells. …”
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952
Discovery and development of ANV419, an IL-2/anti-IL-2 antibody fusion protein with potent CD8+ T and natural killer cell-stimulating capacity for cancer immunotherapy
Published 2024-12-01“…ANV419 preferentially expands CD8+ T cells and natural killer (NK) cells over Tregs and can be safely administered at doses that elicit strong pharmacodynamic effects and efficacy in mouse tumor models. …”
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953
The Relevance of CD117-Immunocytochemistry Staining Patterns to Mutational Exon-11 in c-kit Detected by PCR from Fine-Needle Aspirated Canine Mast Cell Tumor Cells
Published 2014-01-01“…We have demonstrated the usage of fine-needle aspirated MCT cells (FNA-MCT cells) from these specimens as a primary cell source to study the distribution of CD117-immunocytochemistry (CD117-ICC) staining patterns and the frequency of internal tandem duplication- (ITD-) mutant exon-11 of c-kit. …”
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954
供体特异性输血通过CD47-SIRPα信号负调控树突状细胞诱导移植耐受
Published 2010-01-01“…【目的】 探讨CD47-SIRPα信号在供体特异性输血诱导移植耐受中的作用及其机制65377;【方法】 将受体bm1小鼠按不同的移植前预处理分为3组:CD47 WT-DST组65380;CD47 KO-DST组65380;Non-DST组65377;7 d后移植CD47 WT/B6皮片,比较3组皮肤移植物的存活时间;DST后565380;24 h行流式细胞术检测各组受体抗原呈递细胞的活化情况;DST后565380;24 h行流式细胞术和组织免疫学检测供体细胞在受体组织内的分布和存活情况65377;【结果】 CD47 WT-DST组的皮肤移植物存活时间[MST =(46.77 ± 20.01)d]明显比Non-DST组延长(P < 0.0001),而CD47 KO-DST组明显加快皮肤移植物排斥反应,其皮肤移植物存活时间[MST =(13.73 ± 4.56)d]甚至比Non-DST组还短(P < 0.05)65377;行CD47 KO-DST的受体小鼠体内, DC上CD86的表达水平明显高于CD47 WT-DST组和Non-DST组(在5 h,P < 0.01;在24 h,P < 0.001)65377;同样,I-Ab (MHC-Ⅱ)表达水平在CD47 KO-DST的受体小鼠体内也明显高于CD47 WT-DST和Non-DST 组(在5 h,P < 0.01;在24 h,P < 0.05)65377;CD47 KO的供体脾细胞在受体内很快被受体清除65377;【结论】 DST诱导耐受作用中供体细胞表达CD47是必需的,供受体间的CD47-SIRPα引发负性调节信号,负反馈调控DC的成熟和活化,抑制其抗原呈递作用,进而诱导供体特异性耐受65377;…”
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955
CD4 T cell depletion increases memory differentiation of endogenous and CAR T cells and enhances the efficacy of Super2 and IL-33-armored CAR T cells against solid tumors
Published 2025-02-01“…S233 cytokine armoring alone or with CD4 depletion improved effector responses but limited CAR memory T cell generation. …”
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956
The Management of Ureteropelvic Junction Obstruction Presenting with Prenatal Hydronephrosis
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957
Differentiating Latent Tuberculosis from Active Tuberculosis Through Activation Phenotypes and Chemokine Markers HLA-DR, CD38, MCP-1, and RANTES: A Systematic Review and Meta-Analysis
Published 2025-01-01“…Objectives: To assess the diagnostic accuracy of specific biomarkers (HLA-DR + IFNγ + , CD38 + IFNγ + , MCP-1, and RANTES) in differentiating aTB from LTBI. …”
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958
Synthesis, Characterization, and Biological Activity of Mn(II), Fe(II), Co(II), Ni(II), Cu(II), Zn(II), and Cd(II) Complexes of N-Thiophenoyl-N′-Phenylthiocarbohydrazide
Published 2013-01-01“…The complexes were found to have compositions [Mn(H TPTH)2], [Co(TPTH) (H2O)2], [Ni(TPTH) (H2O)2], [Cu(TPTH)], [Zn(H TPTH)], [Cd(H TPTH)2], and [Fe(H TPTH)2(EtOH)]. The magnetic and electronic spectral studies suggest square planar geometry for [Cu(TPTH)], tetrahedral geometry for [Zn(TPTH)] and [Cd(H TPTH)2], and octahedral geometry for rest of the complexes. …”
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