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    Integrated microbiome, transcriptome and metabolome insight into the alleviating mechanisms of sheep milk in a DSS-induced colitis mouse model by Wenna Yao, Ruilin Du, Shuo Yan, Teligun Bao, Huimin Zhang, Fang Yang, Yue Xue, Yulong Zhao, Siqin Bao, Xihe Li, Yongli Song

    Published 2025-02-01
    “…Inflammatory bowel disease (IBD) is a recurrent inflammatory disease affecting the gastrointestinal tract, including ulcerative colitis (UC) and Crohn's disease (CD). IBD mainly causes intestinal mucosal injury, intestinal flora and metabolite disturbance. …”
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  3. 25003

    Stromal architecture and fibroblast subpopulations with opposing effects on outcomes in hepatocellular carcinoma by Yifei Cheng, Xiaofang Chen, Li Feng, Zhicheng Yang, Liyun Xiao, Bin Xiang, Xiaodong Wang, Dongbin Liu, Penghui Lin, Jieyi Shi, Guohe Song, Wulei Qian, Boan Zhang, Yanan Xu, Zheng Gao, Lv Chen, Yingcheng Wu, Jiaqiang Ma, Youpei Lin, Haichao Zhao, Lihua Peng, Xuebin Mao, Yang Liu, Hao Hou, Mingyu Yang, Yuan Ji, Xiaoying Wang, Jian Zhou, Xun Xu, Xiyang Liu, Wu Wei, Xiaoming Zhang, Qiang Gao, Hu Zhou, Yidi Sun, Kui Wu, Jia Fan

    Published 2025-01-01
    “…We discovered two functional units, one is the intratumor inflammatory hub featured by CAF-FAP plus CD8_PDCD1 proximity and the other is the marginal wound-healing hub with CAF-C7 plus Macrophage_SPP1 co-localization. …”
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    Technical note: A fast and reproducible autosampler for direct vapor equilibration isotope measurements by J. Pyschik, S. Seeger, S. Seeger, B. Herbstritt, M. Weiler

    Published 2025-01-01
    “…VapAuSa measurements have a negligible measurement bias (<span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M4" display="inline" overflow="scroll" dspmath="mathml"><mrow><mo>&lt;</mo><mn mathvariant="normal">1</mn><mo>×</mo><msup><mn mathvariant="normal">10</mn><mrow><mo>-</mo><mn mathvariant="normal">13</mn></mrow></msup></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="56pt" height="14pt" class="svg-formula" dspmath="mathimg" md5hash="84c4c517ec0a57ff59e5ade77a9a4f92"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="hess-29-525-2025-ie00001.svg" width="56pt" height="14pt" src="hess-29-525-2025-ie00001.png"/></svg:svg></span></span> ‰ for both <span class="inline-formula"><i>δ</i><sup>2</sup></span>H and <span class="inline-formula"><i>δ</i><sup>18</sup></span>O) and similar measurement repeatability compared to manual analysis of identical samples (<span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M7" display="inline" overflow="scroll" dspmath="mathml"><mrow><msup><mi mathvariant="italic">δ</mi><mn mathvariant="normal">2</mn></msup><mrow class="chem"><mi mathvariant="normal">H</mi></mrow><mo>=</mo><mo>±</mo><mn mathvariant="normal">4.5</mn></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="58pt" height="14pt" class="svg-formula" dspmath="mathimg" md5hash="a1756e064ae97bf3fb705c96a90e616e"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="hess-29-525-2025-ie00002.svg" width="58pt" height="14pt" src="hess-29-525-2025-ie00002.png"/></svg:svg></span></span> ‰ and <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M8" display="inline" overflow="scroll" dspmath="mathml"><mrow><msup><mi mathvariant="italic">δ</mi><mn mathvariant="normal">18</mn></msup><mrow class="chem"><mi mathvariant="normal">O</mi></mrow><mo>=</mo><mo>±</mo></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="49pt" height="14pt" class="svg-formula" dspmath="mathimg" md5hash="5b12edb21efb09f699689b93d39aa9cd"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="hess-29-525-2025-ie00003.svg" width="49pt" height="14pt" src="hess-29-525-2025-ie00003.png"/></svg:svg></span></span>0.58 ‰ for VapAuSa measurements vs. …”
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