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24961
Standardised packaging, minimum excise tax, and RYO focussed tax rise implications for UK tobacco pricing.
Published 2020-01-01Get full text
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24962
The 7 Rights: an active reflection tool to develop risk awareness for outdoor first aid education
Published 2019-02-01Get full text
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Radiosensitizing capacity of fenofibrate in glioblastoma cells depends on lipid metabolism
Published 2025-02-01“…A comparative protein and lipid analysis revealed striking differences in the two GBM cell lines: LN18 cells exhibited a significantly higher membrane expression density of the fatty acid (FA) cluster protein transporter CD36 than U87 cells, a higher expression of glycerol-3-phosphate acyltransferase 4 (GPAT4) which supports the production of large lipid droplets (LDs), and a lower expression of diacylglycerol O-acyltransferase 1 (DGAT1) which regulates the formation of small LDs. …”
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Power calculation of novel single-piece aspheric diffractive trifocal intraocular lens
Published 2019-09-01Get full text
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24969
A prospective observational cohort study of HIV infection in Indonesia: baseline characteristics and one-year mortality
Published 2025-01-01“…Other factors at enrollment significantly associated with mortality were a CD4 + count < 200 (aHR 8.02, 95% CI: 2.69–23.86; compared to ≥ 350), age 40–49 years (aHR 2.19, 95% CI 1.23–3.87; compared to 18–29 years) and being underweight (aHR 1.84, 95% CI: 1.18–2.85; compared to normal weight). …”
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Bio-impedancemetry an essential tool in the obesity screening of patients with chronic renal failure [La bio-impédancemétrie un outil indispensable dans le dépistage de l’obésité c...
Published 2024-12-01“…The highest rate of obesity according to BMI was found in patients with stage 3b CD (p=0.003). Obesity by percentage of body fat estimated by the bio-impedancemetry method was identified in 60% of patients. …”
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کاربست تحلیل SWOT با تفکیک عوامل طبیعی و انسانی در مدیریت یکپارچه حوزه آبخیز میخساز در استان مازندران...
Published 1402-09-01Get full text
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Outcomes with bridging radiation therapy prior to chimeric antigen receptor T-cell therapy in patients with aggressive large B-cell lymphomas
Published 2025-01-01“…BackgroundSelect patients with relapsed/refractory aggressive B cell lymphoma may benefit from bridging radiation (bRT) prior to anti-CD19-directed chimeric antigen receptor T cell therapy (CAR-T). …”
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تدوین راهبردهای سازگاری با خشکسالی در استان لرستان با استفاده از مدل SWOT
Published 2023-12-01Get full text
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CREB3L1 facilitates pancreatic tumor progression and reprograms intratumoral tumor-associated macrophages to shape an immunotherapy-resistance microenvironment
Published 2025-01-01“…Furthermore, CREB3L1-induced TAM polarization toward an M2 phenotype and reduced the infiltration of CD8+ T cells. Clinically, CREB3L1 correlated with immune cell signatures as well as immune checkpoint blockade (ICB) treatment response and outcome that CREB3L1aberrant activation indicated poorer efficacy and worse prognosis than the low in PDAC which might empower clinical decision.Conclusions Collectively, this study revealed CREB3L1 facilitated PDAC progression, shaped an immune exclude tumor microenvironment and distinguished therapy response and outcome of ICB therapy indicating CREB3L1 could be a promising novel molecular target and biomarker for PDAC treatment.…”
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