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Deep learning on CT scans to predict checkpoint inhibitor treatment outcomes in advanced melanoma
Published 2024-12-01Get full text
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Knockout of the inhibitory receptor TIGIT enhances the antitumor response of ex vivo expanded NK cells and prevents fratricide with therapeutic Fc-active TIGIT antibodies
Published 2023-12-01“…Since NK cells express TIGIT and Fc-receptor CD16, Fc-active anti-TIGIT may deplete NK cells via fratricide, which has not been studied.Methods CRISPR-Cas9-based TIGIT knockout (KO) was performed in expanded NK cells. …”
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Individual-network based predictions of microbial interaction signatures for response to biological therapies in IBD patients
Published 2025-01-01“…Inflammatory Bowel Disease (IBD), which includes Ulcerative Colitis (UC) and Crohn’s Disease (CD), is marked by dysbiosis of the gut microbiome. …”
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Radiation hazards from natural radionuclides contained in rice from former tin mining land
Published 2024-11-01Get full text
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Exploring the impact of aging on motor imagery abilities: a systematic review with meta-analysis
Published 2025-01-01Get full text
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Lower respiratory tract microbiome dysbiosis impairs clinical responses to immune checkpoint blockade in advanced non‐small‐cell lung cancer
Published 2025-01-01“…Microbiome‐derived metabolites reshaped the immune microenvironment in the lower respiratory tract by releasing inflammatory cytokines and chemokines, which was partially achieved by metabolite‐mediated tumoral inflammatory products and reduction of CD8+ effective T cells and M1 phenotypes macrophages in malignant lesions. …”
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Zoonotic transmission of novel Influenza A variant viruses detected in Brazil during 2020 to 2023
Published 2024-12-01Get full text
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The factors impacting on Gleason score upgrading in prostate cancer with initial low Gleason scores
Published 2025-02-01Get full text
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