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24201
Habitat suitability modeling for Posidonia oceanica distribution along a Mediterranean region (NW Italy)
Published 2025-02-01Get full text
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24202
Noncanonical roles of ATG5 and membrane atg8ylation in retromer assembly and function
Published 2025-01-01Get full text
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24203
Lymphoid Progenitor Cells from Childhood Acute Lymphoblastic Leukemia Are Functionally Deficient and Express High Levels of the Transcriptional Repressor Gfi-1
Published 2013-01-01“…Interestingly, a number of quiescence-associated transcription factors were elevated, including the transcriptional repressor Gfi-1, which was highly expressed in primitive CD34+ cells. Together, our findings reveal major functional defects in the primitive hematopoietic component of ALL BM. …”
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Construction of a novel cuproptosis-related gene signature and integrative analyses in cholangiocarcinoma
Published 2025-01-01“…The comprehensive results showed that a low-risk score was correlated with metabolism-related pathways, high infiltration of CD8 T cells, B cells, and M1 macrophages, active immunity and less aggressive phenotypes, high chemotherapeutic sensitivity, and more benefit from immunotherapy. …”
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Pancreatic cancer cell-intrinsic transglutaminase-2 promotes T cell suppression through microtubule-dependent secretion of immunosuppressive cytokines
Published 2025-01-01“…Also, pretreatment of TGM2high PDOs with sublethal doses of the spindle poisons paclitaxel or vincristine increased CD8+T cell activation and sensitized PDOs toward T cell-mediated cytotoxicity.Conclusions These findings indicate that targeting microtubular function therapeutically may enhance antitumor T cell responses by impacting activity of immunosuppressive cytokines in the PDAC microenvironment.…”
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Immune Profile Differences between IgG4-Related Diseases and Primary Sjögren’s Syndrome
Published 2025-01-01“…The natural killer (NK) cells (p = 0.004), CD4+ T cells (p = 0.028), and TBNK cells (p = 0.040) were increased in IgG4-RD compared to pSS. …”
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24212
Modelling height to crown base using non-parametric methods for mixed forests in China
Published 2025-03-01Get full text
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Migración interna y ciudades de América Latina: efectos sobre la composición de la población
Published 2012-01-01Get full text
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24218
Boosting the durability of RuO2 via confinement effect for proton exchange membrane water electrolyzer
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24219
Remodeling of tumor microenvironments by EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer
Published 2025-02-01“…We used digital spatial profiling to analyze non-small cell lung carcinomas in 25 patients before and after EGFR tyrosine kinase inhibitor (TKI) treatment, including 14 patients treated with first-line osimertinib, focusing on CD45-positive immune regions and pan-cytokeratin-positive tumor regions. …”
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Hyperbaric oxygen potentiates platelet-rich plasma composition and accelerates bone healing
Published 2025-03-01Get full text
Article