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    The effect of physical cues on platelet storage lesion by Lihan Cheng, Lu Wang, Shichun Wang, Qi Liu, Ronghua Diao, Chunyan Yao

    Published 2025-12-01
    “…The hard centrifugation group showed the highest level of CD62P expression throughout the storage.Conclusion: our results indicate that agitation can mitigate PSL by supplying sufficient O2 during preservation, shear stress may cause PSL immediately after the physical cues were applied; however, hydrostatic pressure induced by filtration is negligible for its effects on PSL. …”
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    Instationary metabolic flux analysis reveals that NPC1 inhibition increases glycolysis and decreases mitochondrial metabolism in brain microvascular endothelial cells by Bilal Moiz, Matthew Walls, Viviana Alpizar Vargas, Anirudh Addepalli, Callie Weber, Andrew Li, Ganesh Sriram, Alisa Morss Clyne

    Published 2025-01-01
    “…Finally, we found that co-treatment with hydroxypropyl-β cyclodextrin (HPβCD) partially restored metabolic phenotype in U18666A-treated BMECs, suggesting that this drug may have therapeutic effects on the brain endothelium in NP-C. …”
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    Novel nanocomposite synthesis of carboxymethyl cellulose coated to zero-valent iron supported on chitosan for simultaneous removal of heavy metals and pesticides in water: Performa... by Ahmad Abo Markeb, Javier Moral-Vico, Antoni Sánchez, Xavier Font

    Published 2025-01-01
    “…The NC shows 96.91 %, 90.00 %, 60.61 %, 52.73 %, and 40.43 % simultaneous removal of Cr(VI), As(V), Cd(II), Pb(II) and Mn(II), respectively. Also, it demonstrates a significant simultaneous elimination of organochlorine pesticides: DDE, heptachlor, endrin aldehyde, endosulfan, and heptachlor epoxide, being 98.52 %, 94.01 %, 70.98 %, 65.39 %, and 63.02 % the elimination percentage, respectively. …”
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