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Deferiprone ameliorates cisplatin induced peripheral neurotoxicity via ferritinophagy adjustment
Published 2025-02-01Get full text
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21483
Morphological Changes of Renal Corpuscles in Male Mongolian Gerbils at Different Ages
Published 2024-10-01Get full text
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重组人内皮抑素对胃肠间质瘤血管形成及生长的抑制作用
Published 2010-01-01“…【目的】 研究重组人内皮抑素(recombinant human endostatin,rhES)能否抑制胃肠间质瘤(gastrointestinal stromal tumor,GIST)裸鼠移植肿瘤血管生成及生长,探讨抑制血管形成作为GIST治疗方法的可行性65377;【方法】 随机将20只荷瘤裸鼠分为实验组与对照组65377;对照组瘤周注射生理盐水,实验组瘤周注射rhES,连用10 d65377;自用药开始,每5 d测量肿瘤体积,直至用药结束后5 d65377;计算抑瘤率和肿瘤缩小率65377;比较实验组与对照组肿瘤体积65380;微血管密度(microvascular density,MVD)65380;bcl-2阳性表达率65380;凋亡指数(AI)及实验组治疗前后肿瘤体积差异是否具有显著性65377;【结果】 用药前实验组与对照组肿瘤体积无差别(P = 0.628)65377;用药后实验组肿瘤体积逐渐减小65377;用药结束后5 d,实验组肿瘤体积与用药前及对照组相比均明显缩小(P = 0.000),抑瘤率86.5%,肿瘤缩小率为55.5%65377;所有瘤株CD117均为阳性表达65377;实验组MVD低于对照组(P = 0.020)65377;实验组bcl-2阳性表达率均低于对照组(P = 0.023)65377;实验组AI高于对照组(P = 0.020)65377; 【结论】 rhES抑制GIST血管生成65380;促进肿瘤细胞凋亡及遏制肿瘤生长,有可能成为治疗GIST的有效方法之一65377;…”
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Severe Symptomatic Primary CMV Infection in Inflammatory Bowel Disease Patients with Low Population Seroprevalence
Published 2018-01-01“…Eight patients with IBD (UC = 3, IBD-U = 1, CD = 4) presented with primary CMV infection. Patients presented with both gastrointestinal and extraintestinal symptoms. …”
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"The COVID-19 pandemic in BRICS: Milestones, interventions, and molecular epidemiology".
Published 2024-01-01Get full text
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RBM47 is a novel immunotherapeutic target and prognostic biomarker in gliomas
Published 2025-01-01“…Single-cell sequencing and immunofluorescence assays confirmed the enrichment of RBM47 in CD163 + macrophages. Therefore, RBM47 plays a vital role in the immune microenvironment of gliomas and may be a potential immunotherapy target.…”
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Calculation of cams with concave profile in the MATHCAD system
Published 2022-02-01Get full text
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Courses design based on perspective human-centered learning design
Published 2024-12-01Get full text
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Targeting autophagy to enhance chemotherapy and immunotherapy in oral cancer
Published 2025-01-01Get full text
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21495
Disease Stage-Associated Alterations in Learning and Memory through the Electroacupuncture Modulation of the Cortical Microglial M1/M2 Polarization in Mice with Alzheimer’s Disease...
Published 2020-01-01“…Besides, electroacupuncture at the Shenting and Baihui acupoints not only suppressed M1 marker (iNOS/IL-1β) expression but also increased the M2 marker (CD206/Arg1) expression in those regions. We propose that electroacupuncture at the Shenting and Baihui acupoints could regulate microglial polarization and decrease Aβ plaques to improve learning and memory in mild AD mice.…”
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New Echocardiographic Findings Correlate with Intramyocardial Inflammation in Endomyocardial Biopsies of Patients with Acute Myocarditis and Inflammatory Cardiomyopathy
Published 2013-01-01“…LSR and LS correlate significantly with lymphocytic infiltrates (for CD3 r=0.7, P<0.0001, and LFA-1 r=0.8, P<0.0001). …”
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SDG space: Revealing the structure and complementarities among sustainable development goals in China
Published 2025-01-01Get full text
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