Fatty Acids of Erythrocyte Membranes and Blood Serum in Differential Diagnosis of Inflammatory Bowel Diseases by M. V. Kruchinina, I. O. Svetlova, M. F. Osipenko, N. V. Abaltusova, A. A. Gromov, M. V. Shashkov, A. S. Sokolova, I. N. Yakovina, A. V. Borisova

“…The IBDs group included 50 patients with UC, 41 patients with CD, 19 patients with UCC. An exacerbation of the disease was revealed in 42 patients (84 %) with UC, 34 patients with CD (82.9 %) and 11 people with UCC (57.9 %). …”
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The efficacy of neoadjuvant immunotherapy and lymphocyte subset predictors in locally advanced esophageal squamous cell carcinoma: A retrospective study by Ruotong Wang, Shaodi Wen, Xiaoyue Du, Jingwei Xia, Bowen Hu, Yihan Zhang, Guoren Zhou, Feng Jiang, Xiaomin Lu, Miaolin Zhu, Xinyu Xu, Bo Shen

“…Among ICT group, a lower posttreatment CD4+/CD8+ ratio indicated longer DFS and reduced posttreatment B cells indicated longer OS. …”
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Impact of prior CAR T-cell therapy on mosunetuzumab efficacy in patients with relapsed or refractory B-cell lymphomas by Elise A. Chong, Elicia Penuel, Ellen B. Napier, Rachel K. Lundberg, Lihua E. Budde, Mazyar Shadman, Matthew J. Matasar, Nancy L. Bartlett, Ian W. Flinn, Francesc Bosch, Keith Fay, Andre Goy, Anita Kumar, Loretta J. Nastoupil, Michael C. Wei, Mei Wu, Shen Yin, Joseph A. Fraietta, Emeline R. Chong, Stephen J. Schuster

“…Abstract: Mosunetuzumab and other CD20/CD3 bispecific antibodies (BsAbs) have efficacy in B-cell lymphomas relapsing after or refractory to CD19-directed chimeric antigen receptor (CAR)–modified T cells (CAR-T). …”
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Assessment of Physicochemical Properties of Rituximab Related to Its Immunomodulatory Activity by Mariana P. Miranda-Hernández, Carlos A. López-Morales, Nancy D. Ramírez-Ibáñez, Nelly Piña-Lara, Nestor O. Pérez, Aarón Molina-Pérez, Jorge Revilla-Beltri, Luis F. Flores-Ortiz, Emilio Medina-Rivero

“…Rituximab is a chimeric monoclonal antibody employed for the treatment of CD20-positive B-cell non-Hodgkin’s lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, granulomatosis with polyangiitis and microscopic polyangiitis. …”
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A Nomogram Based on Laboratory Data, Inflammatory Bowel Disease Questionnaire and CT Enterography for Activity Evaluation in Crohn’s Disease by Zhang H, Shen Y, Cao B, Zheng X, Zhao D, Hu J, Wu X

“…Han Zhang,1,* Yi Shen,1,* Bo Cao,2 Xiaomin Zheng,1 Dehan Zhao,3 Jing Hu,4 Xingwang Wu1 1Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, People’s Republic of China; 2Department of Radiology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, People’s Republic of China; 3Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, Anhui, 230022, People’s Republic of China; 4Department of Gastroenterology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jing Hu, The First Affiliated Hospital of Anhui Medical University, Department of Gastroenterology, Hefei, Anhui, 230022, People’s Republic of China, Tel +86 139-5510-7753, Email hujing810@163.com Xingwang Wu, The First Affiliated Hospital of Anhui Medical University, Department of Radiology, Hefei, Anhui, 230022, People’s Republic of China, Tel +86 153-7533-0696, Email duobi2004@126.comBackground: Accurately assessing the activity of Crohn’s disease (CD) is crucial for determining prognosis and guiding treatment strategies for CD patients.Objective: This study aimed to develop and validate a nomogram for assessing CD activity.Methods: The semi-automatic segmentation method and PyRadiomics software were employed to segment and extract radiomics features from the spectral CT enterography images of lesions in 107 CD patients. …”
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Differential Recruitment of Dendritic Cells Subsets to Lymph Nodes Correlates with a Protective or Permissive T-Cell Response during Leishmania (Viannia) Braziliensis or Leishmania... by A. K. Carvalho, K. Carvalho, L. F. D. Passero, M. G. T. Sousa, V. L. R. da Matta, C. M. C. Gomes, C. E. P. Corbett, G. E. Kallas, F. T. Silveira, M. D. Laurenti

“…Considering the T lymphocyte response, an increase of effector, activated, and memory CD4+ T-cells was observed in Lb infection. Interleukin- (IL-) 4- and IL-10-producing CD4+ and CD8+ T-cells were present in both La and Lb infection; however, interferon- (IFN-) γ-producing CD4+ and CD8+ T-cells were detected only in Lb infection. …”
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Efficacy of small-diameter core decompression with platelet-rich plasma in early osteonecrosis of the femoral head: a retrospective study by Haiwei Tang, Yahao Lai, Enze Zhao, Kai Zhou, Gang Chen, Zongke Zhou

“…Nineteen patients (23 hips) underwent small-diameter CD + PRP (group A) and 21 patients (28 hips) received conventional CD (group B) and follow-up was conducted every 3 months. …”
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Insulin-Attenuated Inflammatory Response of Dendritic Cells in Diabetes by Regulating RAGE-PKCβ1-IRS1-NF-κB Signal Pathway: A Study on the Anti-Inflammatory Mechanism of Insulin in... by Liding Zhao, Ya Li, Qingbo Lv, Min Wang, Yi Luan, Jiale Song, Guosheng Fu, Junbo Ge, Yunzeng Zou, Wenbin Zhang

“…The bone marrow-derived DCs (BMDCs) were obtained from C57BL/6 mice. CD83, CD86, and type II major histocompatibility complex (MHC-II) of BMDCs were measured by flow cytometry. …”
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A High-Salt Diet Disturbs the Development and Function of Natural Killer Cells in Mice by Xiaokang Zeng, Yan Li, Weibiao Lv, Xinhuai Dong, Chong Zeng, Liming Zeng, Zibo Wei, Xu Lin, Yanning Ma, Qiang Xiao

“…Further, the development of NK cells in mice was evaluated, and it was found that HSD reduced the effective NK cell subset (CD27+CD11b-). Moreover, it was also found that the ability of NK cells to secrete CD107a and IFN-γ in HSD-fed mice was decreased following stimulation with RMA-S and YAC-1 tumor cells. …”
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The Role of Circulating Regulatory T Cell Levels on Subclinical Atherosclerosis and Cardiovascular Risk Factors in Women with Systemic Lupus Erythematosus by Mario García-Carrasco, Pamela Soto-Santillán, Claudia Mendoza-Pinto, Rebeca González-Ramírez, Ana Lidia López-Carmona, Pamela Munguía-Realpozo, Ivet Etchegaray-Morales, Socorro Méndez-Martínez, José Luis Gálvez-Romero, Aurelio López-Colombo, Alejandro Ruiz-Arguelles

“…Flow cytometry was used to analyze Foxp3 and Helios expression in peripheral blood CD4 T cells. A significantly higher level of absolute CD4+CD25+FoxP3high T cells was present in patients with abnormal carotid IMT compared with those without (1.795±4.182 cells/μl vs. 0.274±0.784 cells/μl; p=0.003). …”
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PD-L1 positive platelets mediate resistance to immune checkpoint inhibitors in patients with colorectal cancer by Jiacheng Li, Jia Liu, Shifeng Yang, Yu Xia, Qingzhe Meng, Biying Sun, Yansong Liu, Bin Zhao, Jiaqi Jin, Hui Xu, Lihong Wang, Pengxia Zhang, Zhuoxin Cheng

“…Animal experiments revealed that antiplatelet pharmacological agents and genetic knockout of platelets potentiated the antitumour effect of the PD-L1 mAb treatment in a CD8 + T cell dependent manner. Conclusions Our data suggest that PD-L1 positive platelets suppress CD8 + T cell immunity. …”
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EMAP II Expression Is Increased on Peripheral Blood Cells from Non-Hodgkin Lymphoma by Manal Mohamed Saber

“…This study showed coexpression of EMAP II and CD36 on peripheral lymphocytes in NHL patients but not in healthy controls (P<0.001). …”
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Dual-Polarized Planar Phased Array Analysis for Meteorological Applications by Chen Pang, Peter Hoogeboom, François Le Chevalier, Herman W. J. Russchenberg, Jian Dong, Tao Wang, Xuesong Wang

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Monitoring Disease Progression and Therapeutic Response in a Disseminated Tumor Model for Non-Hodgkin Lymphoma by Bioluminescence Imaging by Margarethe Köberle, Kristin Müller, Manja Kamprad, Friedemann Horn, Markus Scholz

“…By stably transfecting a luciferase expression vector, we created two bioluminescent human non-Hodgkin lymphoma cell lines, Jeko1(luci) and OCI-Ly3(luci), that are CD20 positive, a prerequisite to studying rituximab, a chimeric anti-CD20 antibody. …”
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Multi-detector computer tomography as effective method for Crohn's disease diagnostics by A. A. Tikhonov, A. V. Gorinov, I. V. Zarodnyuk, I. L. Khalif, Ye. S. Korolevsky

“…Signs of CD were obtained by CT-enterography in 62 patients (55,9%), in all of these cases it was possible to establish localization of process, to estimate its spread and reveal complications.Results. …”
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Complexation of Z-ligustilide with hydroxypropyl-β-cyclodextrin to improve stability and oral bioavailability by Lu Yapeng, Liu Siyuan, Zhao Yu, Zhu Li, Yu Shuqin

“…LIG is capable of forming an inclusion complex with HP-b-CD and the stoichiometry of the complex was 1:1. …”
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T Cell/Histiocyte-Rich Large B Cell Lymphoma of the Thymus: A Diagnostic Pitfall by Jie Xu, Xiaojun Wu, Vishnu Reddy

“…The excised lymph nodes were replaced by diffuse infiltrate of small CD3+ lymphocytes and histiocytes with intermingled large CD20+ B lymphoma cells scattered throughout the section. …”
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Castleman disease misdiagnosed as immunoglobulin G4-related disease: a case report by Na Li, LiFen Xu, Xiaoxia Liu, Pengjia Wu, Jun Liu, Jiashun Zeng

“…Subsequent pathological biopsy and immunohistochemical analysis ultimately confirmed the diagnosis of CD. This case underscores the limitations of relying solely on serum IgG4 levels as a diagnostic marker to distinguish CD from IgG4-RD. …”
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Inadequate clearance of translocated bacterial products in HIV-infected humanized mice. by Ursula Hofer, Erika Schlaepfer, Stefan Baenziger, Marc Nischang, Stephan Regenass, Reto Schwendener, Werner Kempf, David Nadal, Roberto F Speck

“…These conditions allowed higher levels of plasma LPS and CD8+ cell activation, which were associated with lower CD4+/CD8+ cell ratios and higher viral loads. …”
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